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| 1 | Assessment of vascular invasion in gastric cancer: A comparative study显示文摘AIM: To evaluate and compare detection of lymphatic and blood vessel invasion (LVI and BVI) by hematox-ylin-eosin (HE) and immunohistochemistry (IHC) in gastric cancer specimens, and to correlate with lymph node status. METHODS: IHC using D2-40 (a lymphatic endothelial marker) and CD34 (a pan-endothelial marker) was performed to study LVI and BVI in surgical specimens froma consecutive series of 95 primary gastric cancer cases. The results of the IHC study were compared with the detection by HE using McNemar test and kappa index. The morphologic features of the tumors and the presence of LVI and BVI were related to the presence of lymph node metastasis. A χ2 test was performed to obtain associations between LVI and BVI and other prognostic factors for gastric cancer. RESULTS: The detection rate of LVI was considerably higher than that of BVI. The IHC study identified eight false-positive cases and 13 false-negative cases for LVI, and 24 false-positive cases and 10 false-negative cases for BVI. The average Kappa value determined was moderate for LVI (k=0.50) and low for BVI (k=0.20). Both LVI and BVI were statistically associated with the presence of lymph node metastasis (HE: P=0.001, P=0.013, and IHC: P=0.001, P=0.019). The mor-phologic features associated with LVI were location of the tumor in the distal third of the stomach (P=0.039), Borrmann's macroscopic type (P=0.001), organ inva-sion (P=0.03) and the depth of tumor invasion (P=0.001). The presence of BVI was related only to the depth of tumor invasion (P=0.003). CONCLUSION: The immunohistochemical identification of lymphatic and blood vessels is useful for increasing the accuracy of the diagnosis of vessel invasion and for predicting lymph node metastasis. | Letícia Trivellato Gresta Ismael Alves Rodrigues-Júnior Lúcia Porto Fonseca de Castro Geovanni Dantas Cassali Mnica Maria Demas lva-res Cabral | 2013 | World Journal of Gastroenterology2013，19，24： | 8 |
| 2 | Removal of chromium fi-om aqueous solutions by diatomite treated with microemulsion 显示文摘 | Dantas T N Neto A A Moura M C | 2001 | Water Research2001，35，9： | 1 |
| 3 | An organic selenium compound attenuates apomorphine-induced stereotypy in mice 显示文摘 | MACHADOA M S ROSA R M DANTAS A S | 2006 | Neurosc Lett2006，410，2： | 1 |
| 4 | Functional characteriza- tion of the antibiotic resistance reservoir in the human microflora显示文摘 | SOMMER M O DANTAS G CHURCH G M | 2009 | Science2009，325，5944： | 1 |
| 5 | Evaluation of copper slag to catalyze advanced oxidation processes for the removal of phenol in water显示文摘 | Huanosta-Gutierrez T F Dantas R Ramirez-Zamora R M | 2012 | Journal of Hazardous Materials2012，213，： | 1 |
| 6 | Granzyme B,FAS-Ligand and perforin during acutecellilar rejection episodes after kidney transplantation:Comparison between blood renal aspirates显示文摘 | PNetto MV Fonseca BAL Dantas M | 2002 | Transplantation Pro2002，34，： | 1 |
| 7 | Creatine kinase and lactate dehydrogenase responses after upper - body resistance exercise with different rest intervals 显示文摘 | Rodrigues B M Dantas E de Salles B F | 2010 | J Strength Cond Res2010，24，6： | 1 |
| 8 | Oil sludge treatment by photocatalysis applying black and white light显示文摘 | ROCHA O R S DANTAS R F DUARTE M M M B | 2010 | Chemical Engineering Journal2010，157，1： | 1 |
| 9 | Renal injury in apolipoprotein E-deficient mice显示文摘 | Segerer S Dantas M | 2002 | Lab Invest2002，82，8： | 1 |
| 10 | Selective adsorption of gold over copper cyanocomplexes on activated carbon 显示文摘 | Souza C Majuste D Dantas M S S | 2014 | Hydro- metallurgy2014，，： | 1 |
| 11 | Chromium adsorption by chitosan impregnated with mieroemulsion显示文摘 | Castro Dantas T N Dantas Neto A A A Moura M C P | | 0，，： | 1 |
| 12 | The Relationship between Quality of Life, Sense of Coherence and Self-esteem in Persons after Coronary Artery bypass Graft Surgery显示文摘 | Dantas R A Motzer S A Ciol M A | 2002 | Int J Nurs Stud2002，39，7： | 1 |
| 13 | Screening analysis of natural gas with respect to methane content by near-infrared spectrometry显示文摘 | Hebertty V. Dantas Mayara F. Barbosa Elaine C.L. Nascimento Pablo N.T. Moreira Roberto K.H. Galv?o Mário C.U. Araújo | 2014 | Microchemical Journal2014，，： | 1 |
| 14 | Characterization and kinetic compensation effect of corn biodiesel显示文摘 | DANTAS M B ALMEIDA A A F CONCEICAO M M FERNANDES V J Jr SANTOS I M G SILVA F C SOLEDADE L F B SOUZA A G | 2007 | J Therm Anal Calorim2007，87，3： | 1 |
| 15 | Adefovir dipivoxil, review of a novel acyclic nucleoside analogue显示文摘 | Danta M Dusheiko G | 2004 | Int J Clin Pract2004，58，9： | 1 |
| 16 | An- tibody phage display libraries: contributions to oncology显示文摘 | Dantas Barbosa C de Marcelo Brigido M Maranhao A Q | 2012 | Int J Mol Sci2012，13，5： | 1 |
| 17 | A strategy for selecting calibration samples for multivariate modeling显示文摘 | Dantas H A Galvao R K H Araujo M C U | 2004 | Chemom Intell Lab Syst2004，72，1： | 1 |
| 18 | Car-bon dioxide-nitrogen separation through adsorption on acti-vated carbon in a fixed bed显示文摘 | DANTAS T L P LUNA F M T SILVAJR I J | 2011 | Chemical EngineeringJournal2011，169，1： | 1 |
| 19 | Chemical composition and micorbicidal activity of extracts from brazilian and bulgarian porpolis显示文摘 | SALOMAO K DANTAS A P BORBA C M | 2004 | Lett Applt Micorbio12004，38，： | 1 |
| 20 | Effect of solvent content on the separation and the energy consumption of extractive distillation columns显示文摘 | De Figueiredo M F Brito Karoline Dantas Ramos W B | 2015 | Chemical Engineering Communi- cations2015，202，9： | 1 |
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