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| 1 | Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation. | Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 3 |
| 2 | Acute surgical emergencies in inflammatory bowel disease显示文摘 | Dale F Berg Anil M Bahadursingh Donald L Kaminski Walter E Longo | 2002 | The American Journal of Surgery2002，，： | 2 |
| 3 | In vivo tracing of major rat brain pathways using manganese-enhanced magnetic resonance imaging and three-dimensional digital atlasing显示文摘 | Leergaard T B Bjaalie J O Devor A Wald L L Dale A M | 2003 | Neuroimage2003，20，： | 1 |
| 4 | True metabolizable ener- gy of fats at low level dietary inclusion 显示文摘 | DALE N M FALLER H L | 1982 | Poultry Science1982，61，12： | 1 |
| 5 | Time trends in autism and in MMR immunization coverage in Califomia 显示文摘 | Dales L Hammer S J Smith NJ | 2001 | JAMA2001，285，： | 1 |
| 6 | Magnetic resonance imaging in the evaluation of a high-velocity gunahot wound to the thigh显示文摘 | Parker S Jarvis L Dale R | 1997 | Br J Surg1997，84，8： | 1 |
| 7 | The genome organization of banana bunchy top virus analysis of six ss-DNA components 显示文摘 | Burns T M Harding R M Dale J L | 1995 | J Gen Virol1995，76，： | 1 |
| 8 | Improved and standardized methodology for oil spill fingerprinting显示文摘 | Daling P S Faksness L G Hansen A B | 2002 | Environmental Forensics2002，3，3： | 1 |
| 9 | Wind and drift currents in the South China Sea显示文摘 | DALE W L | 1956 | Malaysian J Trop Geogr1956，8，： | 1 |
| 10 | The development of responsibility in children显示文摘 | Dale B Harris | 1954 | The Elementary School Journal1954，，2： | 1 |
| 11 | Cytosolic, and pH in guinea pig ventricular myocytes exposed to anoxia and reoxygenation显示文摘 | Ralenkotter L Dales C Deleamp T J | 1997 | Am J Physiol1997，276，62： | 1 |
| 12 | Pepsin-digestibility of contaminated estuarine sediments显示文摘 | TURNER A HENON D N DALE J L L | 2001 | Estuarine Coastal and Shelf Science2001，53，： | 1 |
| 13 | Complete dentures for a child with hypohidrotic ecto- dermal dysplasia:A clinic report 显示文摘 | Van Ramos Dale L | 1995 | J Prosthetic Dent1995，74，： | 1 |
| 14 | Risk tolerance and asset allocation for investors nearing retirement 显示文摘 | Govind H Kenneth S C Dale L D | 2000 | Financial Services Review2000，，9： | 1 |
| 15 | Effects of ammonia fiber explosion treatment on activity of endoglucanase from Acidothermus cellulolyticus in transgenic plant 显示文摘 | Teymouri F Alizadeh H Laureano-Perez L Dale B Sticklen M | 2004 | Appl Biochem Biotechnol2004，116，： | 1 |
| 16 | Advancing Working and Learning Through Critical Action Research: Creativity and Constraints显示文摘 | Bellman L Bywood C Dale S | 2003 | Nurse Educ Pract2003，3，4： | 1 |
| 17 | Geochemistry and mineralogical residences of trace elements in oil shales from Julia Creek, Queensland, Australia 显示文摘 | PATIERSON J H RAMSDEN A R DALE L S | 1986 | Chemical Geology1986，55，： | 1 |
| 18 | Early weaning reduces small intestinal alkaline phosphatase expression in pigs显示文摘 | Dale L Yang C B Tania A | 2010 | J Nutr2010，140，： | 1 |
| 19 | Xolloid related: A novel BMP1/Tolloi&related metalloprotease is ex- pressed during early Xenopus development显示文摘 | Dale L Evans W Goodman S A | 2002 | Mech- anisms of Development2002，119，2： | 1 |
| 20 | Feeling Close: Emotional Intensity Reduces Perceived Psychological Distance显示文摘 | Van Boven L Kane J McGraw A P Dale J | 2010 | Journal of Personality and Social Psychology2010，98，6： | 1 |
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