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| 1 | 原发性结直肠癌解剖部位在美国白人与中国人之间分布趋势的比较显示文摘目的比较研究美国白人患者与中国患者原发性结直肠癌(CRC)的部位分布特点,并探讨与年龄、性别的关系。方法回顾性分析1990~2000年间美国克里夫兰佛罗里达临床中心结直肠外科690例和中国第一军医大学南方医院普通外科870例连续完整的CRC患者资料。结果CRC部位分布、年龄和性别在美国白人患者和中国患者间差异有显著性意义。位于近侧结肠者为36.3%比26.0%(P<0.001),位于远侧结直肠者为63.7%比74.0%(P<0.001)。近年来,在白人男性中远侧结直肠癌有减少和近侧结肠癌有增加的趋势,80岁以上老年组更明显。在近侧结肠癌中白人男性较女性更常见(P<0.01)。肿瘤分布及性别构成在中国患者中无变化。白人患者平均年龄69.8岁,而中国患者为48.3岁(P<0.001)。结论美国白人较中国人易患近侧结肠癌,其部位分布近年有从远侧向近侧结肠转移而重新分布的趋势。中国人易患远侧结直肠癌,其发病年龄较美国白人明显年轻。 | 卿三华 饶开运 蒋会勇 Stevan D.Wexner | 2002 | 中华胃肠外科杂志2002，5，2： | 7 |
| 2 | aTME:走向繁荣还是中途夭折?显示文摘Since Sylla et al.[1]introduced transanal total mesorectal excision(taTME)in 2010,there has been rapid global uptake of this approach,predicated upon the postulated advantage of improved visualization of and access to the deep pelvic anatomy.This approach has been proposed for locally adries have demonstrated the procedural safety and short-and long-term oncologic adequacy of taTME in carefully selected patients,when performed by experienced high-volume taTME surgeons[1–7]. | Liang Kang Patricia Sylla Sam Atallah Massaki Ito Steven D.Wexner Jian-Ping Wang | 2020 | Gastroenterology Report2020，8，1： | 3 |
| 3 | 结直肠癌微创手术的重新评价与思考显示文摘纵观整个外科史,外科医师一直在努力优化外科术式,减少手术创伤。过去30年间,随着新技术和新术式的开展,结直肠微创手术取得了巨大的进展。腹腔镜手术已显示出等同于甚至优于开放术式的治疗效果。而且,腹腔镜手术已经突破了传统的界限,衍生出单孔腹腔镜、经自然腔道内镜手术及机器人手术等新的微创术式。本文回顾了微创手术的发展历程,并对目前各种结直肠微创术式进行了评价。 | Mahmoud Abu Gazala Steven D.Wexner | 2017 | Gastroenterology Report2017，5，1： | 2 |
| 4 | Postoperative ileus in colorectal surgery:is there any difference between laparoscopic and open surgery?显示文摘Background:Postoperative ileus is a major complication of patients undergoing abdominal surgery.The purpose of this study was to determine the effects of operative time and the method of surgery on postoperative ileus.Methods:After institutional review board approval,121 patients were studied in two groups.Group 1 consisted of 86 patients with colorectal cancers and Group 2 included 35 patients with diverticulitis.Various surgical procedures were performed in both groups.In all patients,the nasogastric(NG)tube was removed after termination of surgery.Clear liquids were offered commencing on the first postoperative day,followed by a regular diet as tolerated.GI-1 was the postoperative time to toleration of clear liquids,whereas GI-2 was the postoperative time to first bowel movement or flatus and toleration of a regular diet.Statistical analysis was performed using a linear regression model by disease with the first bowel movement or flatus as the dependent variable and operative time and category as explanatory variables.Results:Vomiting after oral feeding occurred in 18(20.9%)patients with cancer and in 7(20.0%)patients with diverticular disease.An NG tube was reinserted in 13(15.1%)patients in the cancer group and in 3(8.6%)patients in the diverticular disease group.In patients with cancer,the duration of operation was associated with GI-2(P=0.011),whereas in patients with diverticulitis,the duration of operation was associated with GI-1(P=0.001)and GI-2(P=0.044).In the diverticulitis group,a significant relationship was found between GI-2 and operative category(P=0.03).Conclusion:Longer operations led to more prolonged postoperative ileus after both laparoscopy and laparotomy,regardless of malignant or benign pathology.In anticipation of and/or following longer operations,surgeons should consider measures to shorten postoperative ileus. | Mehdi Fesharakizadeh Diana Taheri Shahaboddin Dolatkhah Steven D.Wexner | 2013 | Gastroenterology Report2013，1，2： | 1 |
| 5 | The differences between American and Chinese patients with Crohn’s disease显示文摘 | C. H.Luo S. D.Wexner Q. S.Liu L.Li E.Weiss R. H.Zhao | 2011 | Colorectal Disease2011，，2： | 1 |
| 6 | Consensus conference on the stapled transanal rectal resection (STARR) for disordered defaecation显示文摘 | M. L.Corman A.Carriero T.Hager A.Herold D. G.Jayne P.‐A.Lehur D.Lomanto A.Longo A. F.Mellgren J.Nicholls P.‐O.Nystr?m A. J.Senagore A.Stuto S. D.Wexner | 2006 | Colorectal Disease2006，，2： | 1 |
| 7 | Physiological and clinical outcome of anterior sphincteroplasty显示文摘 | L.Oliveira J.Pfeifer S. D.Wexner | 2005 | Br J Surg2005，，4： | 1 |
| 8 | Outcome and predictors of success of biofeedback for constipation显示文摘 | R.Gilliland S.Heymen D. F.Altomare U. C.Park D.Vickers S. D.Wexner | 2005 | Br J Surg2005，，： | 1 |
| 9 | Colorectal polyps and polyposis syndromes显示文摘A polyp is defined as any mass protruding into the lumen of a hollow viscus.Colorectal polyps may be classified by their macroscopic appearance as sessile(flat,arising directly from the mucosal layer)or pedunculated(extending from the mucosa through a fibrovascular stalk).Colorectal polyps may also be histologically classified as neoplastic or as non-neoplastic(hyperplastic,hamartomatous,or inflammatory).The neoplastic polyps are of primary importance because they harbor a malignant potential,which represents a stage in the development of colorectal cancer.For this reason,it is essential to identify these polyps at a sufficiently early stage,when a simple outpatient procedure to remove them can interrupt the development of colorectal cancer and prevent disease and death.When invasive carcinoma arises in a polyp,careful consideration must be given to ensuring the adequacy of treatment.Although most neoplastic polyps do not evolve into cancer,it is well accepted that the majority of colorectal carcinomas evolve from adenomatous polyps;the sequence of events leading to this transformation is referred to as the adenoma-to-carcinoma sequence.The presence of a systemic process that promotes the development of multiple gastro-intestinal polyps is termed‘polyposis’.Hereditary gastro-intestinal polyposis syndromes account for approximately 1%of all cases of colorectal cancer and are associated with a broad spectrum of extra-colonic tumors.Early detection and accurate classification of these syndromes are essential,in order to initiate a surveillance program for the early detection of cancer.Several polyposis syndromes have been described,each having its own genetic basis and characteristic polyp distribution,clinical presentation,and malignancy risk.Diagnostic modalities and treatment options for neoplastic polyps-as well as the most prevalent polyposis syndromes-are reviewed below. | Noam Shussman Steven D.Wexner | 2014 | Gastroenterology Report2014，2，1： | 1 |
| 10 | Ileal pouch–anal anastomosis in elderly patients: is there a difference in morbidity compared with younger patients?显示文摘 | R. A.Pinto J.Canedo S.Murad‐Regadas S. F.Regadas E. G.Weiss S. D.Wexner | 2011 | Colorectal Disease2011，，： | 1 |
| 11 | Adhesion prevention and reduction:current status and future recommendations of a multinational interdisciplinary consensus conference显示文摘 | Michael P.Diamond Steven D.Wexner Gere S.diZereg | | 0，，03： | 1 |
| 12 | 再次括约肌成形术:效果能长久吗?显示文摘目的:本研究旨在调查再次括约肌成形术(RS)患者的长期结局。方法:利用一个前瞻性数据库对1988年11月至2011年12月间接受RS手术的排便失禁患者进行回顾性分析。通过问卷和电话调查进行克利夫兰临床排便失禁评分(CCFFIS,0分最佳,20分最差)和排便失禁生活质量评分(FIQoL,4.1分最佳,1分最差)。手术成功定义为截至末次随访未进一步行排便手术、无造口且CCFFIS评分<9。计量资料的比较采用Wilxoxon和Mann-Whitney U检验。采用双元逻辑回归分析来确定手术成功的预测因素。结果:84例患者接受RS手术,其中56例(66.7%)获得74月的中位随访(12-283月)。末次随访时,平均CCFFIS评分由16.563.7下降至11.966.6(P<0.001)。12例(21.4%)患者接受后续便秘手术,3例(5.4%)进行了永久性造口,判定为手术失败。随访结束时,18例(32.1%)患者CCFFIS评分<9,16例获得长期成功。24例患者接受了FIQoL评分,平均2.6分(1.04.1分)。术后CCFFIS评分与FIQoL显著负相关(Spearman相关系数为0.854,P<0.001)。逻辑回归分析并没有发现任何预测RS成功的临床参数。结论:基于我们的成功标准,RS手术的长期成功率(中位随访时间74月)并不理想。 | Kwangdae Hong Giovanna Dasilva John T.Dollerschell David Maron Steven D.Wexner | 2016 | Gastroenterology Report2016，4，1： | 0 |
| 13 | COVID-19疫情期间胃肠外科实践策略显示文摘The entire focus of the world has rapidly shifted to the COVID-19 pandemic.Virtually all headlines in print and visual lay media,as well as lead articles in peer-reviewed scientific journals,delve into COVID-19-related issues.Within the world of surgery,information sharing amongst surgeons has helped to define best practices.The rapidity with which this high volume of information is being shared is attestation to the seemingly infinite need for opinions,answers,and especially data.In the absence of a significant body of high-quality data,among the various publications are a plethora of guidelines from organizations,societies,and individual surgical groups.Realizing the dearth of evidence upon which to formulate guidelines,the various publications have included either personal or institutional experiences often in the form of registries or databases or expert consensus-based guidelines[1-5].The manuscript in this edition of Gastroenterology Report by Ke and coworkers[6]offers guidance from,in the authors’words,‘the front-line Chinese GI surgeons’to help the rest of the world to deal with COVID-19.The authors included a myriad of useful information including overall strategies based upon the local establishment of a task force,risk stratification of patients,recommendations for infection prevention in the department of surgical gastroenterology,recommendations for the management of both gastrointestinal(GI)surgery and endoscopy,reflections on perioperative infection-control measures,post-discharge follow-up,and considerations relative to adjuvant chemotherapy. | Steven D.Wexner | 2020 | Gastroenterology Report2020，8，3： | 0 |
| 14 | Surgical outcomes and their relation to the number of prior episodes of diverticulitis显示文摘Purpose:We aimed to investigate the relationship between the number of prior episodes of diverticulitis and outcomes of sigmoid colectomy.Methods:After institutional review board approval,a retrospective review was undertaken based on records of patients who underwent sigmoid resection with anastomosis for diverticulitis between 4 May 2007 and 29 February 2012.Patients were divided into two groups:0–3 attacks(group 1)and4 attacks(group 2).Statistical analyses were performed to determine whether the groups differed on demographic,intra-operative and postoperative variables.Results:We identified 247 patients who underwent sigmoid colectomy for diverticulitis(45 open,202 laparoscopic).The two groups did not differ significantly in age,gender,American Society of Anesthesiologists score,past surgical history,body mass index,length of stay,use of a stoma or number of prior hospitalizations for diverticulitis.Group 1 had a higher rate of abscesses(30.6 vs 6.8%,P<0.001)and fistulas(19.4 vs 0.9%,P<0.001);a longer operative time(190.1 vs 166.3 min,P=0.0024);and higher rates of postoperative complications(45.8 vs 23.3%,P<0.001)and conversion(17.1 vs 4.4%,P=0.0091).The most common surgical complications in groups 1 and 2 were wound infection(35 vs 10)and ileus(20 vs 8).Based on multivariate regression analysis,4 attacks were independently correlated with a lower complication rate(odds ratio=0.512,95%confidence interval=0.266–0.987,P=0.046).Conclusions:Patients who had4 previous attacks of diverticulitis had fewer postoperative complications. | Shota Takano Cesar Reategui Giovanna da Silva David J.Maron Steven D.Wexner Eric G.Weiss | 2013 | Gastroenterology Report2013，1，1： | 0 |
| 15 | 使用球囊扩张器取出结肠镜检查过程中掉落的AmpliEYE显示文摘AmplifEYE can increase the detection rate of adenomatous polyps and stabilize the mucosa for easy biopsy and polypectomy.But it can also become a foreign body when it is dislodged during the procedure.We report a case of dislodged AmplifEYE during colonoscopy that was successfully retrieved using a balloon dilator. | Jihui Li Luke Blake Steven D.Wexner | 2019 | Gastroenterology Report2019，7，2： | 0 |
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