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| 1 | Restoration of energy level in the early phase of acute pediatric pancreatitis显示文摘Acute pancreatitis (AP) is a serious inflammatory disease with rising incidence both in the adult and pediatric populations. It has been shown that mitochondrial injury and energy depletion are the earliest intracellular events in the early phase of AP. Moreover, it has been revealed that restoration of intracellular ATP level restores cellular functions and defends the cells from death. We have recently shown in a systematic review and meta-analysis that early enteral feeding is beneficial in adults; however, no reviews are available concerning the effect of early enteral feeding in pediatric AP. In this minireview, our aim was to systematically analyse the literature on the treatmentof acute pediatric pancreatitis. The preferred reporting items for systematic review(PRISMA-P) were followed, and the question was drafted based on participants, intervention, comparison and outcomes: P: patients under the age of twenty-one suffering from acute pancreatitis; I: early enteral nutrition (per os and nasogastric- or nasojejunal tube started within 48 h); C: nil per os therapy; O: length of hospitalization, need for treatment at an intensive care unit, development of severe AP, lung injury (including lung oedema and pleural effusion), white blood cell count and pain score on admission. Altogether, 632 articles (Pub Med: 131; EMBASE: 501) were found. After detailed screening of eligible papers, five of them met inclusion criteria. Only retrospective clinical trials were available. Due to insufficient information from the authors, it was only possible to address length of hospitalization as an outcome of the study. Our mini-meta-analysis showed that early enteral nutrition significantly(SD = 0.806, P = 0.034) decreases length of hospitalization compared with nil per os diet in acute pediatric pancreatitis. In this minireview, we clearly show that early enteral nutrition, started within 24-48 h, is beneficial in acute pediatric pancreatitis. Prospective studies and better presentation of research are crucially needed to achieve a higher level of evidence. | Dóra Mosztbacher Nelli Farkas Margit Solymár Gabriella Pár Judit Bajor ákos Szucs József Czimmer Katalin Márta Alexandra Mikó Zoltán Rumbus Péter Varjú Péter Hegyi Andrea Párniczky | 2017 | World Journal of Gastroenterology2017，23，6： | 8 |
| 2 | Differentially expressed microRNAs in small cell lung cancer显示文摘 | Miko E Czimmerer Z Csfinky E | 2009 | Exp Lung Res2009，35，8： | 1 |
| 3 | Urocortin 2 acts central-ly to delay gastric emptying through sympathetic pathways while CRF and urocortin 1 inhibitory actions are vagal de- pendent in rats 显示文摘 | Czimmer J Million M Tache Y | 2006 | Am J Physiol Gastrointest Liver Physiol2006，290，： | 1 |
| 4 | miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7AS显示文摘 | Miko E Margtai Z Czimmerer Z | 2011 | FEBS Lett2011，585，8： | 1 |
| 5 | miR-126 inhibitsproliferation of small cell lung cancer cells by targetingSLC7A5显示文摘 | Miko E Margitai Z Czimmerer Z | 2011 | FEBS Lett2011，585，8： | 1 |
| 6 | The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function - from physiology to pathology显示文摘 | Mate Kiss Zsolt Czimmerer Laszlo Nagy | 2013 | The Journal of Allergy and Clinical Immunology2013，，： | 1 |
| 7 | The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function; From physiology to pathology显示文摘 | Kiss M Czimmerer Z Nagy L | 2013 | J Allergy Clin Immunol2013，132，： | 1 |
| 8 | Nuclear receptor mediated mechanisms of macrophage cholesterol metabolism显示文摘 | Nagy ZS Czimmerer Z Nagy L | 2013 | Mol Cell Endocrinol2013，368，1： | 1 |
| 9 | miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5 显示文摘 | Miko E Margitai Z Czimmerer Z | 2011 | FEBS Lett2011，585，8： | 1 |
| 10 | miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5显示文摘 | Miko E Margitai Z Czimmerer Z | 2011 | FEBS Lett2011，585，8： | 1 |
| 11 | Differentially expressed microRNAs in small cell lung cancer显示文摘 | Miko E Czimmerer Z Csanky E | | 0，，： | 1 |
| 12 | miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5显示文摘 | Miko E Margitai Z Czimmerer Z | 2011 | FEBS Lett2011，555，8： | 1 |
| 13 | Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects(mini review)显示文摘 | SzabóIL Czimmer J Szolcsányi J | 2013 | Current pharmaceutical design2013，19，1： | 1 |
| 14 | PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation显示文摘 | Tamas Varga Zsolt Czimmerer Laszlo Nagy | 2011 | BBA - Molecular Basis of Disease2011，，8： | 1 |
| 15 | PPARs are a unique set of fattyacid regulated transcription factors controlling both lipid metabo-lism and inflammation显示文摘 | Varga T Czimmerer Z Nagy L | 2011 | Biochim Biophys Acta2011，1812，8： | 1 |
| 16 | The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology显示文摘 | Kiss M Czimmerer Z Nagy L | 2013 | J Allergy Clin Immunol2013，132，2： | 1 |
| 17 | Differentially expressed microRNAs in small cell lung cancer 显示文摘 | Miko E Czimmerer Z Csanky E | 2009 | Exp Lung Res2009，35，8： | 1 |
| 18 | Differentially expressed mieroRNAs in small cell lung eancer显示文摘 | Miko E Czimmerer Z Csanky E | 2009 | Exp Lung Res2009，35，： | 1 |
| 19 | Gastric mucosal integrity: gastric mucosal blood flow and microcirculation. An overview显示文摘 | Omar M.E. Abdel-Salam József Czimmer András Debreceni János Szolcsányi Gyula Mózsik | 2001 | Journal of Physiology - Paris2001，，1： | 1 |
| 20 | Urocortin 2 acts centrally to delay gastric emptying through sympathetic pathways while CRF and urocortin 1 inhibitory actions are vagal dependent in rats 显示文摘 | Czimmer J Million M Tach Y | 2006 | Am J Physiol Gastrointest Liver Physiol2006，290，3： | 1 |
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