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| 1 | Effect of sedative agent selection on morbidity, mortality and length of stay in patients with increase in intracranial pressure显示文摘BACKGROUND: To identify the effects of sedative agent selection on morbidity, mortality, and length of stay in patients with suspected increase in intracranial pressure. Recent trends and developments have resulted in changes to medications that were previously utilized as pharmacological adjuncts in the sedation and intubation of patients with suspected increases in intracranial pressure. Medications that were previously considered contraindicated are now being used with increasing regularity without demonstrated safety and effectiveness. The primary objective of this study is to evaluate and compare the use of Ketamine as an induction agent for patients with increased intracranial pressure. The secondary objective was to evaluate and compare the use of Etomidate, Midazolam, and Ketamine in patients with increased intracranial pressure. METHODS: We conducted a retrospective chart review of patients transported to our facility with evidence of intracranial hypertension that were intubated before trauma center arrival. Patients were identifi ed during a 22-month period from January 2014 to October 2015. Goals were to evaluate the impact of sedative agent selection on morbidity, mortality, and length of stay.RESULTS: During the review 148 patients were identifi ed as meeting inclusion criteria, 52 were excluded due to incomplete data. Of those the patients primarily received; Etomidate, Ketamine, and Midazolam. Patients in the Ketamine group were found to have a lower mortality rate after injury stratifi cation. CONCLUSION: Patients with intracranial hypertension should not be excluded from receiving Ketamine during intubation out of concern for worsening outcomes. | Brian G.Cornelius Elizabeth Webb Angela Cornelius Kenneth W.G.Smith Srdan Ristic Jay Jain Urska Cvek Marjan Trutschl | 2018 | World Journal of Emergency Medicine2018，9，4： | 4 |
| 2 | Prognosis of luxated non-vital maxillary incisors treated with calcium hydroxide and filled with gutta-percha显示文摘 | | 1992 | Endod Dent Trumatol1992，8，： | 1 |
| 3 | Healing of 208 intra-alveolar root fractures in patients aged 7-17 years显示文摘 | Cvek M Andreasen JO Borum MK | | 0，，02： | 1 |
| 4 | Conservative endodontic treatment of teeth fractured in the middle or apical part o the root显示文摘 | Cvek M Mejare I Andreasen JO | 2004 | Dent Traumatol2004，20，5： | 1 |
| 5 | Effect of topical appli- cation of doxycyeline on pulp revascularization and periodontal healing in reimplanted monkey incisors 显示文摘 | Cvek M Cleaton-Jones P Austin J et at | 1990 | Endod Dent Trauma- tol1990，6，4： | 1 |
| 6 | 1 Pulp reactions to expo- sure after experimental crown fractures or grinding in adult monkeys 显示文摘 | Cvek M Clea ton-Jones PE Austin JC eta | 1982 | J Endod1982，8，9： | 1 |
| 7 | Pulp reactions to exposure after experimental crown fractures or grinding in adult monkeys显示文摘 | Cvek M Cleaton-Jones PE Austin JC | 1981 | J Endod1981，8，9： | 1 |
| 8 | Treatment of non-vital perma-nent incisors with calcium hydroxide显示文摘 | Cvek M Hollender I Nord CE | 1976 | Odontol Revy1976，27，： | 1 |
| 9 | Targeting malignancies with disulfiram (Antabuse):multidrug resistance,angiogenesis,and proteasome显示文摘 | Cvek B | 2011 | Curr Cancer Drug Targets2011，11，3： | 1 |
| 10 | Nonprofit drugs as the salvation of the world' s healthcare systems:the case of Antabuse (disulfiram)显示文摘 | Cvek B | 2012 | Drug Discov Today2012，17，910： | 1 |
| 11 | Global transcrip-tional profiling reveals Streptococcus agalactiae genescontrolled by the MtaR transcription factor显示文摘 | Bryan J D Liles R Cvek U | 2008 | BMCGenomics2008，16，9： | 1 |
| 12 | Pulp reactions toexposure after experimental crown fractures or grinding in adultmonkeys显示文摘 | Cvek M Cleaton - Jones P E Austin J C ef al | 1982 | J Endod1982，8，9： | 1 |
| 13 | Comparison of plantar pres- sures distribution between obese and non-obese children 显示文摘 | Hlava'cVek P Kosteln'kova L | 2008 | Clinical Biomechanics2008，23，： | 1 |
| 14 | Treatment of non-vital permanent incisors with calcium hydroxide显示文摘 | Cvek M Hollender I Nord CE | 1976 | Odontol Revy1976，27，： | 1 |
| 15 | Pulp revascularization in reimplanted immature monkey incisors-predictability and the effect of antibiotic systemic prophylaxis 显示文摘 | Cvek M Cleaton-Jones P Austin J | 1990 | Endod Dent Trauma- tol1990，6，4： | 1 |
| 16 | A clinical report on partial pulpotomy and capping with calcium hydroxide in permanent incisors with complicated crown fracture显示文摘 | Cvek M | 1978 | J Endod1978，4，8： | 1 |
| 17 | Prognosis of luxated non--vital maxillary incisors treated with calcium hydroxide and filled with gutta--percha= A retrospective clinical study 显示文摘 | Cvek M | 1992 | Endod Dent Traumatol1992，8，2： | 1 |
| 18 | Prognosis of luxated non-vital maxillary incisors treated with calcium hydroxide and filled with gutta-percha显示文摘 | Cvek M | 1992 | Endod Dent Trumatol1992，8，： | 1 |
| 19 | Effect of topical application of doxycycline on pulp revascularization and periodontal healing in reimplanted monkey incisors显示文摘 | Cvek M Cleaton-Jones P Austin J | 1990 | Endod Dent Traumatol1990，6，4： | 1 |
| 20 | Rate and predictability of pulp revas-cularization in therapeutically reimplanted permanent incisors显示文摘 | Kling M Cvek M Mejare I | 1986 | Endod Dent Traumatol1986，2，3： | 1 |
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