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| 1 | Astragalus polysaccharide enhances immunity and inhibits H9N2 avian influenza virus in vitro and in vivo显示文摘This study investigated the humoral immunization of Astragalus polysaccharide(APS) against H9N2 avian influenza virus(H9N2 AIV) infection in chickens. The effects of APS treatment on H9N2 infection was evaluated by an MTT [3(4, 5-dimethylthiazol-2-yl)-2, 3-diphenyl tetrazolium bromide] assay and analysis of MHC and cytokine mRNA expression. The effect on lymphocyte and serum antibody titers in vivo was also investigated. IL-4, IL-6, IL-10, LITAF, IL-12 and antibody titers to H9N2 AIV were enhanced in the first week after APS treatment. The results indicated that APS treatment reduces H9N2 AIV replication and promotes early humoral immune responses in young chickens. | Sanpha Kallon Xiaorong Li Jun Ji Cuiying Chen Qianyun Xi Shuang Chang Chunyi Xue Jingyun Ma Qingmei Xie Youngliang Zhang | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 48 |
| 2 | Diagnostic performance of contrast-enhanced ultrasound and enhanced magnetic resonance for breast nodules显示文摘In the current study, we sought to evaluate the diagnostic efficacies of conventional ultrasound(US), contrastenhanced US(CEUS), combined US and CEUS and magnetic resonance imaging(MRI) in detecting focal solid breast lesions. Totally 117 patients with 120 BI-RADS category 4A-5 breast lesions were evaluated by conventional US and CEUS, and MRI, respectively. SonoVue was used as contrast agent in CEUS and injected as an intravenous bolus; nodule scan was performed 4 minutes after bolus injection. A specific sonographic quantification software was used to obtain color-coded maps of perfusion parameters for the investigated lesion, namely the time-intensity curve.The pattern of contrast enhancement and related indexes regarding the time-intensity curve were used to describe the lesions, comparatively with pathological results. Histopathologic examination revealed 46 benign and 74 malignant lesions. Sensitivity, specificity, and accuracy of US in detecting malignant breast lesions were 90.14%, 95.92%, and 92.52%, respectively. Meanwhile, CE-MRI showed sensitivity, specificity, and accuracy of 88.73%, 95.92%, and91.67%, respectively. The area under the ROC curve for combined US and CEUS in discriminating benign from malignant breast lesions was 0.936, while that of MRI was 0.923, with no significant difference between them, as well as among groups. The time-intensity curve of malignant hypervascular fibroadenoma and papillary lesions mostly showed a fast-in/fast-out pattern, with no good correlation between them(kappa <0.20). In conclusion, the combined use of conventional US and CEUS displays good agreement with MRI in differentiating benign from malignant breast lesions. | Cuiying Li Haiyan Gong Lijun Ling Liwen Du Tong Su Shui Wang Jie Wang | 2018 | The Journal of Biomedical Research2018，32，3： | 27 |
| 3 | The Cemented Material Dam: A New, Environmentally Friendly Type of Dam显示文摘 | Jinsheng Jia Michel Lino Feng Jin Cuiying Zheng | 2016 | Engineering2016，2，4： | 23 |
| 4 | Simulation of influence of multi-defects on long-term working performance of high arch dam显示文摘As an integrated structure,an arch dam is assumed to bear loads in its design consideration.However,multi-defects,such as cracks and the opening of transverse joints,are unavoidable during construction and operation.Multi-defects will reduce the structural integrity and stiffness of the dam and affect its working performance and degree of safety.In the current paper,a numerical model of defects and a simulation method of a high arch dam are introduced.The Chencun arch dam is analyzed as a case study.An entire course simulation analysis of the Chencun arch dam from construction to operation is carried out,through which the opening of the transverse and longitudinal joints,formation of cracks,and their influence on deformation and stress of the dam are studied.According to the results of the analysis,appropriate measures should be adopted to prevent the development of cracks,and observation should be strengthened for a more timely discovery of risks. | ZHANG GuoXin ,LIU Yi,ZHENG CuiYing & FENG Fan State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin,Beijing 100038,China China Institute of Water Resources and Hydropower Research,Beijing 100038,China | 2011 | Science China(Technological Sciences)2011，54，S1： | 17 |
| 5 | Adsorptive desulfurization over hierarchical beta zeolite by alkaline treatment显示文摘Hierarchical beta zeolites with SiO2 /Al2O3 molar ratios of 16 to 25 were obtained by alkaline treatment in NaOH solution. The effects of treatment temperature on crystallinity, textural properties and chemical composites were studied by XRD, N2 sorption, FT-IR and XRF techniques. The desulfurization performance of parent and alkaline-treated beta zeolites was investigated by static absorption in four model fuels, containing four sulfur compounds of different molecular sizes like thiophene (TP), 3-methylthiophene (3-MT), benzothiophene (BT) and dibenzothiophene (DBT), respectively. The crystallinity was observed to be successfully maintained when the treatment temperature was below 50 C. Mesoporosity of beta zeolite was evidently developed with alkaline treatment. The formation of mesopore remarkably improved the desulfurization performance for TP, 3-MT, BT and DBT, especially for DBT with larger molecular diameter. Though the addition of toluene in the model fuels resulted in a significant drop of the desulfurization performance of mesoporous beta zeolite, the introduction of cerium ions to some extent mitigated the effect of toluene, which means that both the adsorbents porous structure and the adsorption mode are responsible for the desulfurization performance. The adsorbent of cerium ion-exchanged mesoporous beta showed about 80% recovery of desulfurization after the first regeneration. | Fuping Tian Xiaojian Yang Yanchun Shi Cuiying Jia Yongying Chen | 2012 | Journal of Natural Gas Chemistry2012，21，6： | 11 |
| 6 | Effects of toluene on thiophene adsorption over NaY and Ce(IV)Y zeolites显示文摘Zeolites NaY and Ce(IV)Y were employed as adsorbents to remove organic sulfur compounds from model gasoline(MG) solutions with and without toluene in static adsorption experiments at room temperature(RT) and atmospheric pressure.The adsorbents were characterized by XRD,XRF and pyridine infrared spectrum(IR).The adsorption experiments show that the desulfurization performance of Ce(IV)Y is much better than that of NaY.The sulfur removal over both NaY and Ce(IV)Y decreases with the increase of toluene concentration in MG,however,the decline tendency on Ce(IV)Y is smooth,and it is steep on NaY.FT-IR spectra of thiophene adsorption indicate that thiophene molecules are mainly adsorbed on NaY via π electron interaction,but on Ce(IV)Y,in addition to the π electron interaction,both Ce4+-S direct interaction and protonation of thiophene also play important roles.Toluene molecules are adsorbed on NaY also via π electron interaction.Although the amount of Brnsted acid sites is increased due to the introduction of Ce4+ ions into NaY zeolite,it is not found to influence the adsorption mode of toluene over Ce(IV)Y.Compared with NaY zeolite,the improved desulfurization performance over Ce(IV)Y for removing organic sulfur compounds from MG solution,especially those containing large amount of aromatics,may be ascribed to the direct Ce(IV)-S interaction,which is much resistant to the influence resulted from toluene adsorption. | Yanchun Shi Xiaojian Yang Fuping Tian Cuiying Jia Yongying Chen | 2012 | Journal of Natural Gas Chemistry2012，21，4： | 9 |
| 7 | Microstructures and mechanical properties of Al-Cu-Mn alloy with La and Sm addition显示文摘The effect of single addition of La or Sm on the microstructures and mechanical properties of an Al-Cu-Mn alloy were investigated by microstructure characterization and tensile test.The results show that addition of La or Sm into the Al-Cu-Mn alloy can remarkably increase the density of θ' phase and refine the microstructure,and thus,improves the mechanical properties at room temperature.La addition results in a more considerable increase in the density and refinement of θ' phase than Sm addition.La addition has a more significant contribution on the mechanical properties of the Al-Cu-Mn alloy than Sm addition.In addition,a new phase of Al_6Cu_6La is formed in the Al-Cu-Mn alloy with La addition. | Chen, Zhongwei Chen, Pei Ma, Cuiying | 2012 | Rare Metals2012，31，4： | 8 |
| 8 | Pollutant and Soil Types Influence Effectiveness of Soil-Applied Absorbents in Reducing Rice Plant Uptake of Persistent Organic Pollutants显示文摘Persistent organic pollutants(POPs) in soils are an environmental concern due to their long-term bioavailability, which could be reduced by adding adsorbents. However, testing of these adsorbents is necessary prior to widespread field application. The effects of three adsorbents, nano-organic montmorillonite, nano-organic silicon dioxide(SiO_2), and activated carbon, on hexachlorobenzene(HCB) and pentachlorobenzene(Pe CB) accumulation in rice(Oryza sativa L.) plants were tested in a greenhouse experiment using two soils, a Hydragric Acrisol(Ac) and a Gleyi-Stagnic Anthrosol(An). The bioconcentration factors(BCFs) of HCB and Pe CB to rice roots were 2.3–3.7 and 2.0–3.0 times those to rice shoots, respectively. The applications of the three adsorbents decreased HCB and Pe CB extractability in Ac, while only the application of activated carbon decreased their extractability in An. The bioavailability of HCB and Pe CB to rice plants in Ac was higher than that in An. In Ac, the applications of nano-organic SiO_2 and activated carbon decreased the BCF of HCB to rice roots by 16.1% and 26.8%, respectively, whereas only the application of activated carbon decreased the BCF of Pe CB to rice roots by 31.4%, compared to the control. In An, only the application of activated carbon decreased the BCFs of HCB and Pe CB to rice roots by 22.9% and 18.2%, respectively, compared to the control. However, the application of nano-organic montmorillonite inhibited rice growth in both soils. The results of this study suggested that the effectiveness of adsorbents would vary with pollutant and soil types, providing a reference point for developing efficient adsorbents to reduce the ecological risk of POPs. | LIU Cuiying JIANG Xin MA Yuchun Barbara J.CADE-MENUN | 2017 | Pedosphere2017，27，3： | 8 |
| 9 | Fault plane parameters of Tancheng M81/2 earthquake on the basis of present-day seismological data显示文摘The great Tancheng earthquake of M81/2 occurred in 1668 was the largest seismic event ever recorded in history in eastern China.This study determines the fault geometry of this earthquake by inverting seismological data of present-day moderate-small earthquakes in the focal area.We relocated those earthquakes with the double-difference method and found focal mechanism solutions using gird test method.The inversion results are as follows:the strike is 21.6°,the dip angle is 89.5°,the slip angle is 170°,the fault length is about 160 km,the lower-boundary depth is about 32 km and the buried depth of upper boundary is about 4 km.This shows that the seismic fault is a NNE-trending upright right-lateral strike-slip fault and has cut through the crust.Moreover,the surface seismic fault,intensity distribution of the earthquake,earthquake-depth distribution and seismic-wave velocity profile in the focal area all verified our study result. | Cuiying Zhou Guiling Diao Jie Geng Yonghong Li Ping Xu Xinliang Hu Xiangdong Feng | 2010 | Earthquake Science2010，23，6： | 7 |
| 10 | Fully Fabric-Based Triboelectric Nanogenerators as Self-Powered Human-Machine Interactive Keyboards显示文摘Combination flexible and stretchable textiles with self-powered sensors bring a novel insight into wearable functional electronics and cyber security in the era of Internet of Things.This work presents a highly flexible and self-powered fully fabric-based triboelectric nanogenerator(F-TENG)with sandwiched structure for biomechanical energy harvesting and real-time biometric authentication.The prepared F-TENG can power a digital watch by low-frequency motion and respond to the pressure change by the fall of leaves.A self-powered wearable keyboard(SPWK)is also fabricated by integrating large-area F-TENG sensor arrays,which not only can trace and record electrophysiological signals,but also can identify individuals’typing characteristics by means of the Haar wavelet.Based on these merits,the SPWK has promising applications in the realm of wearable electronics,self-powered sensors,cyber security,and artificial intelligences. | Jia Yi Kai Dong Shen Shen Yang Jiang Xiao Peng Cuiying Ye Zhong Lin Wang | 2021 | Nano-Micro Letters2021，13，7： | 6 |
| 11 | 肝纤维化的生物标志物研究现状显示文摘目前肝纤维化的辅助诊断手段主要包括组织病理学诊断、血液学诊断和影像学诊断。组织病理学诊断是诊断肝纤维化的“金标准”。但鉴于其存在固有的缺陷:是一种损伤性检查、不能动态检测和重复进行、存在取材差异、同时还存在诊断者之间的个体判读误差等原因,因而限制了它的广泛应用。血液学检查目前仍是临床最常用的辅助诊断手段。 | 高春芳 Axel M.Gressner Cuiying Chen | 2008 | 中华肝脏病杂志2008，16，3： | 6 |
| 12 | Accelerated anaerobic dechlorination of DDT in slurry with Hydragric Acrisols using citric acid and anthraquinone-2,6-disulfonate(AQDS)显示文摘The application of electron donor and electron shuttle substances has a vital influence on electron transfer,thus may affect the reductive dechlorination of 1,1,1-trichoro-2,2-bis(p-chlorophenyl)ethane(DDT) in anaerobic reaction systems.To evaluate the roles of citric acid and anthraquinone-2,6-disulfonate(AQDS) in accelerating the reductive dechlorination of DDT in Hydragric Acrisols that contain abundant iron oxide,a batch anaerobic incubation experiment was conducted in a slurry system with four treatments of(1) control,(2) citric acid,(3) AQDS,and(4) citric acid + AQDS.Results showed that DDT residues decreased by 78.93%–92.11% of the initial quantities after 20 days of incubation,and 1,1-dichloro-2,2-bis(4-chlorophenyl)-ethane(DDD) was the dominant metabolite.The application of citric acid accelerated DDT dechlorination slightly in the first 8 days,while the methanogenesis rate increased quickly,and then the acceleration effect improved after the 8th day while the methanogenesis rate decreased.The amendment by AQDS decreased the Eh value of the reaction system and accelerated microbial reduction of Fe(III) oxides to generate Fe(II),which was an efficient electron donor,thus enhancing the reductive dechlorination rate of DDT.The addition of citric acid + AQDS was most efficient in stimulating DDT dechlorination,but no significant interaction between citric acid and AQDS on DDT dechlorination was observed.The results will be of great significance for developing an efficient in situ remediation strategy for DDT-contaminated sites. | Cuiying Liu Xianghua Xu Jianling Fan | 2015 | Journal of Environmental Sciences2015，27，12： | 5 |
| 13 | BRCA1 affects global DNA methylation through regulation of DNMT1显示文摘在 CpG 岛的全球 DNA hypomethylation 结合了本地 hypermethylation 是为乳癌的一个特点,然而,位于这个变化下面的机制留下逃犯。在这研究,我们证明 DNMT1,编码 methylation 维护酶,是 BRCA1 的一个 transcriptional 目标。BRCA1 通过一个潜在的 OCT1 地点和绑定绑在 DNMT1 基因的倡导者为维持 transcriptional 被要求在老鼠和人的房间的倡导者的活跃配置。我们进一步证明 BRCA1 的那损害功能在在 premaligant 阶段在一个 BRCA1 变异的老鼠模型检验的纸巾的几种类型导致全球 DNA hypomethylation,印的 genomic 的损失,和一种开的染色质配置。BRCA1 缺乏也与几 protooncogenes 的显著地增加的表达式层次被联系,包括 c-Fos,哈地岬,和 c-Myc,与在肿瘤的一个更高的表达式,当时乳房的上皮的房间显示了的 premalignant 在肿瘤和控制之间的一个中间的状态。在人的临床的样品,有 DNMT1 的减少的层次的 BRCA1 相互关联的减少的表示,和 CpG 岛的减少的 methylation。因此, BRCA1 通过断然调整 DNMT1 表示阻止全球 DNA hypomethylation,并且这为联系 BRCA1 的乳癌形成提供机制之一。 | Vivek Shukla Xavier Coumoul Tyler Lahusen Rui-Hong Wang Xiaoling Xu Athanassios Vassilopoulos Cuiying Xiao Mi-Hye Lee Yan-Gao Man Mutsuko Ouchi Toru Ouchi Chu-Xia Deng | 2010 | Cell Research2010，20，11： | 5 |
| 14 | SINGULAR BEHAVIORS OF INTERFACIAL CRACKS IN 2D MAGNETOELECTROELASTIC BIMATERIALS显示文摘The singular characteristics of stress,electric displacement and magnetic induction fields near the tip of impermeable interfacial cracks in two-dimensional magnetoelectroelastic bimaterials are studied using the generalized Stroh formalism.Two types of singularities are ob-tained:one is the oscillating singularity 1/2±iε,the other is the non-oscillating singularity 1/2±κ.It is found that the non-zero parameters ε and κ cannot coexist for one transversely isotropic MEE bimaterial,a similar result is obtained for transversely isotropic piezoelectric bimaterials. | Cuiying Fan Youhe Zhou Han Wang Minghao Zhao | 2009 | Acta Mechanica Solida Sinica2009，22，3： | 5 |
| 15 | High efficiency production of ginsenoside compound K by catalyzing ginsenoside Rb1 using snailase显示文摘The rare ginsenoside Compound K(C-K) is attracting more attention because of its good physiological activity and urgent need. There are many pathways to obtain ginsenoside C-K, including chemical and biological methods. Among these, the conversion of PPD-type ginsenosides by enzymatic hydrolysis is a trend due to its high efficiency and mild conditions. For effectively extracting from the other panaxadiol saponins, the conversion process for ginsenoside C-K was investigated using snailases in this study. The univariate experimental design and response surface methodology were used to determine the optimal hydrolysis conditions for the conversion of ginsenoside Rb1 into ginsenoside C-K by snailases. The optimum conditions were as follows: p H 5.12, temperature 51 °C, ratio of snailase/substrate 0.21, and reaction time 48 h. On the basis of these parameters, the addition of 1.0 mmol·L^(-1) ferric ion was found to significantly improve the enzymolysis of snailases for the first time. With the above conditions, the maximum conversion rate reached 89.7%, suggesting that the process can obviously increase the yield of ginsenoside C-K. The bioassay tests indicated that the ginsenoside C-K showed anti-tumor activity in a series of tumor cell lines. Based on these results, we can conclude that the process of rare ginsenoside CK production by enzymolysis with snailase is feasible, efficient, and suitable for the industrial production and application. | Zhiguang Duan Chenhui Zhu Jingjing Shi Daidi Fan Jianjun Deng Rongzhan Fu Rong Huang Cuiying Fan | 2018 | Chinese Journal of Chemical Engineering2018，26，7： | 5 |
| 16 | Linkage map and QTL mapping of red flesh locus in apple using a R1R1×R6R6 population显示文摘The red flesh in apple fruit is a desired trait by consumers and it is associated to the anthocyanin content,which is mainly controlled by MdMYB10 with a R6 promoter.In this study,a high-density linkage group was constructed using the‘Fuji’x‘Red3’population which contained homozygous alleles R1R1 and R6R6,respectively.The linkage group consists of 7630 SNPs along 17 linkage groups,spanning 2270.21 cM,with an average density of 0.30 cM permarker.The cyanidin-3-galactoside concentration was used as the phenotypic data in QTL analysis.Moreover,one QTL peak which was flaked by two markers,marker2187260 to marker2173766,with LOD scores of 4.49 was detected.This QTL ranged from 0 to 40.79 cM on the top of linkage group(LG16).In addition one candidate molecular marker(marker2175442)in this QTL was identified,which was significant correlated with the flesh cyanidin-3-galactoside concentration.These genetic findings enrich the breeding basis of fruit flesh coloration in apple. | Chengquan Yang Guangya Sha Tao Wei Baiquan Ma Cuiying Li Pengmin Li Yangjun Zou Lingfei Xu Fengwang Ma | 2021 | Horticultural Plant Journal2021，7，5： | 4 |
| 17 | Pricking and penetrating moxibustion therapy in patients with refractory insomnia: a randomized and controlled clinical trial显示文摘OBJECTIVE: To observe the clinical effect of pricking and penetrating moxibustion therapy on refractory insomnia.METHODS: Totally 60 subjects were randomly divided into treatment group and control group, 30 in each group. The treatment group was treated with pricking and penetrating moxibustion therapy, the control group with penetrating moxibustion therapy, the treatment was given once every day, two groups of patients were treated 20 times,compared the efficacy, pinsburgh sleep quality index(PSQI) and Traditional Chinese Medicine symptom, safety evaluation between the two groups.RESULTS: Compared with 10, 20 times after the treatment, the effective rate of the treatment group(93.3%) higher than that of the control group(80.0%)(P < 0.05); Compared with beforetreatment, 20 times after treatment, the PSQI and TCM symptom pattern scores of the two groups were significantly decreased(P < 0.01); Compared with 10, 20 times after the treatment, the treatment group are better than the control group in improving the total score and the integral of PSQI(P <0.05 or P < 0.01); The treatment group are better than the control group in improving the TCM symptom pattern score, difficulty in going to sleep, palpitation, amnesia, fidget, sweating, impaired concentration(P < 0.01 or P < 0.05).CONCLUSION: The pricking and penetrating moxibustion therapy is safe and effective in the treatment of refractory insomnia and the treatment can improve the curative effect of the therapy that uses penetrating moxibustion only. | Chen Yan Gao Xiyan Sun Cuiying | 2018 | Journal of Traditional Chinese Medicine2018，38，5： | 4 |
| 18 | DEM investigation on the effect of sample preparation on the shear behavior of granular soil显示文摘 | Beibing Dai Jun Yang Cuiying Zhou | 2016 | Particuology2016，14，2： | 4 |
| 19 | Adiponectin attenuates lipopolysaccharide-induced cell injury of H9c2 cells by regulating AMPK pathway显示文摘Adiponectin,an adipokine synthesized and secreted majorly by adipose tissue,is reported to exert cardioprotective properties via anti-inflammation and antiapoptosis.Lipopolysaccharide(LPS)is a common inflammation and apoptosis inducer of cardiomyocytes.However,few studies have reported the roles of adiponectin on LPS-induced inflammation as well as apoptosis of H9c2 cells,and the possible mechanisms of these effects.In the present study,we found that adiponectin significantly relieved LPS-induced cytotoxicity including decreased viability and elevated LDH release,inhibited LPS-triggered inflammation,which is evidenced by increases in release of TNF-α,IL-1β as well as IL-6,and attenuated the enhanced rates of apoptotic cells as well as increased caspase-3 activity caused by LPS in H9c2 cells.In addition,our data demonstrated that adiponectin upregulated AMP-activated protein kinase(AMPK)activation of H9c2 cells with or without LPS administration.Moreover,we found that blocking AMPK pathway by compound c attenuated the protective effects of adiponectin against the cytotoxicity,inflammatory response,and apoptosis of H9c2 cells resulted from LPS.Our observations bring novel insights for understanding the mediatory role of AMPK pathway implicated in the protective effects of adiponectin against LPS-induced cardiotoxicity. | Rui Hao Guoying Su Xiaolin Sun Xiangran Kong Cuiying Zhu Guohai Su | 2019 | Acta Biochimica et Biophysica Sinica2019，51，2： | 4 |
| 20 | Recent progress on high-pressure and hightemperature studies of fullerenes and related materials显示文摘Polymerization of fullerenes is an interesting topic that has been studied for almost three decades.A rich polymeric phase diagram of C60 has been drawn under a variety of pressure P and temperature T conditions.Knowledge of the targeted preparation and structural control of fullerene polymers has become increasingly important because of their utility in producing novel fullerenebased architectures with unusual properties and potential applications.This paper focuses on the polymeric phases of fullerenes and their derivatives under high P and/or high T.First,the polymerization behavior and the various polymeric phases of C60 and C70 under such conditions are briefly reviewed.A summary of the polymerization process of intercalated fullerenes is then presented,and a synthetic strategy for novel structural and functional fullerene polymers is proposed.Finally,on the basis of the results of recent research,a proposal is made for further studies of endohedral fullerenes at high P. | Cuiying Pei Lin Wang | 2019 | Matter and Radiation at Extremes2019，4，2： | 3 |
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