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| 1 | Regulation of the G1 phase of the mammalian cell cycle显示文摘In any multi-cellular organism, the balance between cell division and cell death maintains a constant cell number. Both cell division cycle and cell death are highly regulated events. Whether the cell will proceed through the cycle or not, depends upon whether the conditions required at the checkpoints during the cycle are fulfilled. In higher eucaryotic cells, such as mammalian cells, signals that arrest the cycle usually act at a G1 checkpoint. Cells that pass this restriction point are committed to complete the cycle. Regulation of the GI phase of the cell cycle is extremely complex and involves many different families of proteins such as retinoblastoma family cyclin dependent kinases, cyclins, and cyclic kinase inhibitors. | DONJERKOVIC DUBRRAVKA DAVID W SCOTT (Department of Immunology, Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD) | 2000 | Cell Research2000，10，1： | 18 |
| 2 | Activation-induced cell death in B lymphocytes显示文摘Upon encountering the antigen (Ag), the immune system can either develop a specific immune response or enter a specific state of unresponsiveness, tolerance. The response of B cells to their specific Ag can be activation and proliferation, leading to the immune response, or anergy and activation-induced cell death (AICD), leading to tolerance. AICD in B lymphocytes is a highly regulated event initiated by crosslinking of the B cell receptor (BCR). BCR engagement initiates several signaling events such as activation of PLCr, Ras, and PI3K, which generally speaking, lead to survival. However, in the absence of survival signals (CD40 or IL-4R engagement), BCR crosslinking can also promote apoptotic signal transduction pathways such as activation of effector caspases, expression of pro-apoptotic genes, and inhibition of pro-survival genes. The complex interplay between survival and death signals determines the B cell fate and, consequently, the immune response. | DONJERKOVIC DUBRAVKA, DAVID W SCOTT (Department of Immunology, Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD, 20855. USA) | 2000 | Cell Research2000，10，3： | 6 |
| 3 | Factors influencing mercury accumulation in three species of forage fish from Caddo Lake, Texas, USA显示文摘Most studies that have examined mercury (Hg) contamination of fish have focused on game species feeding near the top of the food web, while studies that examine forage fish that feed near the base of the food web are rare. We conducted a survey of Hg contamination in three species of forage fish, brook silverside (Labidesthes sicculus), threadfin shad (Dorosoma petenense) and gizzard shad (Dorosoma cepedianum), from Caddo Lake, Texas, USA and found species-specific differences in Hg concentrations. We examined total length, age, trophic position (determined using δ15N), and growth rate of forage fish as factors that could have influenced within-and between-species differences in Hg concentration. Total length and age were the best predictors of within-species differences in Hg concentration. Between-species differences in Hg concentrations were most strongly influenced by trophic position. | Matthew M Chumchal Ray W Drenner David R Cross K David Hambright | 2010 | Journal of Environmental Sciences2010，22，8： | 3 |
| 4 | Relationship of USDA quality grades to palatability of cooked beef 显示文摘 | SMITH G C SAVELL J W CROSS H R | 1986 | Journal of Food Quality1986，10，： | 1 |
| 5 | Why you should consider object-oriented programming techniques for finite element methods 显示文摘 | Cross J T Masters I Lewis R W | 1999 | International Journal of Numerical Methods for Heat & Fluid Flow1999，9，3： | 1 |
| 6 | Simultaneous axial and rotational electron beam velocity measurement using a phosphor scintillator显示文摘 | He W Cooke S J Cross A W | 2001 | Review of Scientific Instruments2001，72，5： | 1 |
| 7 | Functional expres- sion of purinergic P2 receptors and transient receptor poten- tial channels by the human urothelium显示文摘 | Shabir S Cross W Kirkwood L A | 2013 | Am J Physiol Re- nal Physiol2013，305，3： | 1 |
| 8 | Soil erodibility nomographfor farmland and construction sites显示文摘 | Wischmeier W H Johnson C B Cross B V | 1971 | Journal of Soil and WaterConservation1971，26，： | 1 |
| 9 | Effect of dietary selenium on the response of stressed and unstressed chickens to Escherichia coli challenge and antigen显示文摘 | Larsen C T Pierson F W Cross W B | 1997 | Biological Trace Elements Research1997，58，3： | 1 |
| 10 | Induction of bradyzoite-specific Toxoplasma gondii antigens in cinterferon-treated mouse macrophages显示文摘 | Bohne W Heesemann J Cross U | 1993 | Infect Immun1993，61，： | 1 |
| 11 | Hall probe magnetometer for SSC magnet cables: effect of transport current on magnetization and flux creep显示文摘 | CROSS R W GOLDFARB R B | 1991 | IEEE Transactions on Magnetics1991，27，2： | 1 |
| 12 | Enzymatic synthesis of S-adenosyl-L-methionine from L-methionine and ATP显示文摘 | Cross A Geresh S Celia W | 1983 | Appl Biochem Biotechnol1983，8，5： | 1 |
| 13 | 显示文摘 | Pan W y Daam C Q Cross L E | 1989 | J Appl Phys1989，66，12： | 1 |
| 14 | Pathogenic races of the bacterial blight pathogen of soybeans, Pseudomonas glycinea显示文摘 | Cross J E Kennedy B W Lambert J W | 1966 | Plant Disease Reporter1966，50，8： | 1 |
| 15 | Self- efficacy and locus of control af- fect management of aggression by mental health nurses显示文摘 | Dunn K Elsom S Cross W | 2007 | Issues Ment Health Nurs2007，28，2： | 1 |
| 16 | Soil erod- ibility nomograph for farm land and construction sites 显示文摘 | Wischmeier W H Johnson C B Cross B V | 1971 | Journal of Soil and Water Conservation1971，26，5： | 1 |
| 17 | A Soil ErodibilityNomograph forFarmland and Construction Sites 显示文摘 | Wischmeier W H Johson C B Cross B V | 1971 | J Soil andWater Conserv1971，，26： | 1 |
| 18 | A soil erodibility nomograph for farmland and construction siles显示文摘 | Wischmeier W H Johnson C B Cross B V | 1971 | Jourual of soil and water conservation1971，，5： | 1 |
| 19 | Mathematical model of grate-kiln-cooler process used for induration of ire ore pellets 显示文摘 | YOUNG R W CROSS M @IBSON R D | 1979 | Ironmaking and Steelmaking1979，6，1： | 1 |
| 20 | Stabilization and solidification of lead in contaminated soils显示文摘 | Lin S L Cross W H Chian E S | 1996 | Journal of Hazardous Materials1996，48，： | 1 |
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