|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats显示文摘Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that daidzein exhibits neuroprotective effects on cerebral ischemia. Rat models of middle cerebral artery occlusion were intraperitoneally administered daidzein. Biochemical and immunohistochemical tests showed that superoxide dismutase and nuclear respiratory factor 1 expression levels in the brain tissue decreased after ischemia and they increased obviously after daidzein administration; malondialdehyde level and apoptosis-related cysteine peptidase caspase-3 and caspase-9 immunoreactivity in the brain tissue increased after ischemia and they decreased obviously after daidzein administration. Hematoxylin-eosin staining and luxol fast blue staining results showed that intraperitoneal administration of daidzein markedly alleviated neuronal damage in the ischemic brain tissue. These findings suggest that daidzein exhibits neuroprotective effects on ischemic brain tissue by decreasing oxygen free radical production, which validates the aforementioned hypothesis. | Adem Bozkurt Aras Mustafa Guven Tar?k Akman Adile Ozkan Halil Murat Sen Ugur Duz Y?ld?ray Kalkan Coskun Silan Murat Cosar | 2015 | Neural Regeneration Research2015，10，1： | 4 |
| 2 | Syringaldehyde exerts neuroprotective effect on cerebral ischemia injury in rats through anti-oxidative and anti-apoptotic properties显示文摘There are few studies on the neuroprotective effects of syringaldehyde in a rat model of cerebral ischemia. The study aimed to elucidate the mechanisms underlying the neuroprotective effects of syringaldehyde on ischemic brain cells. Rat models of cerebral ischemia were intraperitoneally administered syringaldehyde. At 6 and 24 hours after syringaldehyde administration, cell damage in the brain of cerebral ischemia rats was obviously reduced, superoxide dismutase activity and nuclear respiratory factor 1 expression in the brain tissue were markedly increased, malondiadehyde level was obviously decreased, apoptosis-related cysteine peptidase caspase-3 and-9 immunoreactivity was obviously decreased, and neurological function was markedly improved. These findings suggest that syringaldehyde exerts neuroprotective effects on cerebral ischemia injury through anti-oxidation and anti-apoptosis. | Aras Adem Bozkurt Guven Mustafa Akman Tar?k Ozkan Adile Sen Halil Murat K?l?coglu Mesut Kalkan Y?ld?ray Silan Coskun Cosar Murat | 2014 | Neural Regeneration Research2014，9，21： | 2 |
| 3 | ameboid cell motility : A model and reverse problem, with an application to live cell imaging data 显示文摘 | COSKUN H LI Y MACKEY M A | 2007 | Journal of Theorotical Biology2007，244，2： | 1 |
| 4 | Mapping and monitoring of coastal wetlands of Cukurova Delta in the Eastern Mediterranean region显示文摘 | SHUA B K TULUHAN Y COSKUN O | 2004 | Biodiversity and Conservation2004，，13： | 1 |
| 5 | Epigenetic regulation of stem cells differentiating along the neural lineage显示文摘 | Coskun V Tsoa R Sun Y E | 2012 | Curt Opin NeurobioI2012，22，5： | 1 |
| 6 | Simple and effective surgical treatment of pilonidal sinus显示文摘 | Omer Faruk Akinci Ali Coskun Ali Uzunk?y | 2000 | Diseases of the Colon & Rectum2000，，5： | 1 |
| 7 | Hemodialysis and protein oxidation products显示文摘 | Coskun C Kural A Doventas Y | 2007 | Ann N Y Acad Sci2007，1100，： | 1 |
| 8 | Mechanism of action of epidermal growth factor induced porcine oocytes maturation显示文摘 | COSKUN S LIN Y C | 1995 | Mol Reprod Dev1995，42，： | 1 |
| 9 | Intestinal ischemia-reperfusion impairs liver regeneration after partial hepatectomy in rats显示文摘 | Atici AE Kaya Y Coskun T | 2003 | Hepatogastroenterology2003，50，51： | 1 |
| 10 | Monilethrix: improvement with acitretin 显示文摘 | Karincaoglu Y Coskun BK Seyhan ME | 2005 | Am J Clin Dermatol2005，6，6： | 1 |
| 11 | Higher hepatis Cvirus concentration in platelets than in plasma in a patient with ITP显示文摘 | ONAN E USKUDAR O COSKUN Y | 2012 | Platelets2012，23，5： | 1 |
| 12 | Monilethrix: improvement with acitretin显示文摘 | Karincaoglu Y Coskun BK Seyhan ME | 2005 | Am J Clin Dermatol2005，6，6： | 1 |
| 13 | Relation Between Clinical Pulmonary Infection Score,C-Reactive Protein,and Procalcitonin and Mortality in Patients With Hospital Acquired Pneumonia显示文摘 | Havlucu Y Coskun A Cam S | 2012 | Chest2012，142，4： | 1 |
| 14 | Serum big endothelin-1 levels in female patients with breast cancer显示文摘 | Yildirim Y Gunel N Coskun U | 2008 | Int Immunopharmacol2008，8，8： | 1 |
| 15 | Sporotrichosis successfully treated with terbinafine and potassium iodide:case report and review of the literature 显示文摘 | Coskun B Saral Y Akpolat N | 2004 | Mycopathologia2004，158，1： | 1 |
| 16 | Mediators of in- flammation in children with type I diabetes meUitus : cytokines in type I diabetic children 显示文摘 | Erbagci AB Tarakeioglu M Coskun Y | 2001 | Clin Biochem2001，34，： | 1 |
| 17 | Severe hepatotoxicity as a result of extended use of omidazole显示文摘 | Coskun Y Erarslan E Dogan M | 2012 | J Clin Gas troenterol2012，46，6： | 1 |
| 18 | Primary Mediastinal Yolk Sac Tumor in a 66 year-old Woman显示文摘 | Coskun U Gunel N Yildirim Y | 2006 | Eur J Surg Oncol2006，31，10： | 1 |
| 19 | Adeno-associated vi-rus-mediated gene transfer of the heart/muscle adenine nu-cleotide translocator(ANT)in mouse显示文摘 | Flierl A Chen Y Coskun PE et a1 | 2005 | Gene Ther2005，12，7： | 1 |
| 20 | Prediction of sites of coronary atherosclerosis progression:In vivo profiling of endothelial shear stress, lumen, and outer vessel wall characteristics to predict vascular behavior显示文摘 | Stone P H Coskun A U Yeghiazarians Y | 2003 | Curr Opin Cardiol2003，18，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员