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| 1 | The promise of liquid biopsy in cancer:a clinical perspective显示文摘The clinical utility of liquid biopsy in cancer treatment will increase as circulating tumor cells(CTCs) analysis move from the enumeration to the real-time measurement of tumor characteristics.Intratumor heterogeneity is becoming increasingly recognized as a major drawback to the shift to personalized medicine.Spatial and temporal heterogeneity might be reflected by the serial assessment of CTCs.Indeed,the developing technologies for CTCs analysis now allow digital genomic and nextgeneration sequencing approaches,able to differentiate molecular subtypes of the disease and to monitor genetic variation over time.The liquid biopsy of cancer might offer a real-time assessment of tumor biology,providing the opportunity to serially evaluate patients most likely to benefit from targeted drugs based on a dynamic characterization of the disease at the molecular level.Although hurdles remain before liquid biopsy is seen in routine clinical practice,the information derived from CTCs may facilitate the real-time identification of actionable mutations in cancer leading the way toward personalized medicine. | Enrico Cortesi Michela Palleschi Valentina Magri Giuseppe Naso | 2015 | Chinese Journal of Cancer Research2015，27，5： | 2 |
| 2 | Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial显示文摘 | Gianluca Masi Fotios Loupakis Lisa Salvatore Lorenzo Fornaro Chiara Cremolini Samanta Cupini Andrea Ciarlo Francesca Del Monte Enrico Cortesi Domenico Amoroso Cristina Granetto Gabriella Fontanini Elisa Sensi Cristiana Lupi Michele Andreuccetti Alfredo Fa | 2010 | Lancet Oncology2010，，9： | 2 |
| 3 | The treatment of sleep disorders in childhood autism with melatonin or behavioral therapy: a randomized waiting list controlled study 显示文摘 | Giannotti F Cortesi F Cerquiglini A | 2008 | Sleep2008，31，： | 1 |
| 4 | Supercritical fluids chromatography for impregnation optimization显示文摘 | Cortesi A Alessi P Kikic I | 2000 | Journal of Supercritical Fluids2000，19，： | 1 |
| 5 | Biological monitoring as a valid tool to assess occupational exposure to mixtures of 2,4-∶2,6-toluene diisocyanate显示文摘 | DE PALMA G CORTESI I GHITTI R | 2012 | Med Lav2012，103，5： | 1 |
| 6 | Dextran cross-linked gelatin microspheres as a drug delivery system显示文摘 | Cortesi R Esposito E Osti M | 1999 | European Journal of Pharmaceutical Sciences1999，47，2： | 1 |
| 7 | Transvaginal ultrasonography versus uterine needle biopsy in the diagnosis of diffuse adenomyosis显示文摘 | Vercellini P Cortesi I De Giorgi O | 1998 | Hum Reprod1998，13，11： | 1 |
| 8 | Acceptability andadherence in a chemoprevention trial among women at increasedrisk for breast cancer attending the Modena Familial Breast andOvarian Cancer Center (Italy) 显示文摘 | Razzaboni E Toss A Cortesi L | 2013 | Breast J2013，19，1： | 1 |
| 9 | Cleistothecia of Uncinula necator, additional source of inoculum in Italian vineyards 显示文摘 | Cortesi P Bisiach M Ricciolini M | 1997 | Phytopathology1997，81，： | 1 |
| 10 | BRCA1 mutations and clinicopathological features in a sample of Italian women with early-onset breast cancer显示文摘 | Turchetti D Cortesi L Federico M | 2000 | Eur J Cancer2000，36，16： | 1 |
| 11 | In vitro comparison of the flexibility of different splint systems used in dental traumatology 显示文摘 | Mazzoleni S Meschia G Cortesi R | 2010 | Dent Traumatol2010，26，1： | 1 |
| 12 | Effect of chemical structure on the solubility of antioxidants in supercritical carbon dioxide: experimental data and correlation 显示文摘 | Cortesi A Kikic I Alessi P | 1999 | J Supecrit Fluids1999，14，： | 1 |
| 13 | Dextran cross-linked gelatin microspheres as a drug delivery-system显示文摘 | Rita Cortesi Elisabetta Esposito Maria Osti Giacomo Squarzoni Enea Menegatti Stanley Spencer Davis Claudio Nastruzzi | 1999 | Eur J Pharm Biopharm1999，47，： | 1 |
| 14 | Increased behavioural responsiveness with complex stimulation in VS and MCS: pre-liminary results 显示文摘 | Di Stefano C Cortesi A Masotti S | 2012 | Brain Inj2012，26，10： | 1 |
| 15 | Quality of life as a primary end point in oncology显示文摘 | Rolia F Cortesi E | 2001 | Ann Oncol2001，12，3： | 1 |
| 16 | Diagnosis of bilateral abdominal cryptorchidism by laparoscopy显示文摘 | Cortesi N Fen-aft P Zambarda E | 1976 | Endoscopy1976，8，1： | 1 |
| 17 | Gelatin microspheres: Influence of preparation parameters and thermal treatment on chemico-physical and biopharmaceutical properties显示文摘 | Esposito E Cortesi R Nastruzzi C | 1996 | Biomaterials1996，17，： | 1 |
| 18 | Linear motion carriage with aerostatic bearings pre-loaded by inclined iron core linear electric motor显示文摘 | SLOCUM ALEXANDER BASARAN MURAT CORTESI ROG-ER | 2003 | PrecisionEngineering2003，27，3： | 1 |
| 19 | Dextran crosslinked gelatin microspheres as a drug delivery system 显示文摘 | Cortesi R Esposito E Osti M | 1999 | Eur J Pharm Biopharm1999，47，2： | 1 |
| 20 | Comparison of vegetative compatibility types in Italian and Swiss subpopulations of Cryphonectria parasitica显示文摘 | CORTESI P RIGLING D HEINIGER U | 1998 | European Journal of Forest Pathology1998，28，3： | 1 |
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