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| 1 | 创伤性脑损伤后蛛网膜下腔出血与长期卒中风险的关系(英文)显示文摘BACKGROUND Recent studies suggest that traumatic brain injury(TBI)is a risk factor for subsequent ischemic stroke,even years after the initial insult.The mechanisms of the association remain unclear.The presence of traumatic subarachnoid hemorrhage(t SAH)may mediate the effect of TBI on long-term stroke risk,as it has previously been linked to short-term vasospasm and delayed cerebral ischemia.METHODS Using administrative claims data,we conducted a retrospective cohort study of acute care hospitalizations.Patients discharged with a first-recorded diagnosis of t SAH were followed for a primary diagnosis of stroke.They were matched to patients with TBI but not t SAH.Cox proportional hazards modeling was used to assess the association between t SAH and stroke while adjusting for covariates.RESULTS:We identified 40 908 patients with TBI(20 454 patients with t SAH)who were followed for a mean of 4.3+1.8 years.A total of 531 had an ischemic stroke after discharge.There was no significant difference in stroke risk between those with t SAH(1.79%;95%confidence interval[CI]1.54%-2.08%)versus without t SAH(2.12%;95%CI 1.83%-2.44%).The same pattern was found in adjusted analyses even when the group was stratified by age-group or by proxies of TBI severity.CONCLU-SIONS:Our findings do not support a role of t SAH in mediating the association between TBI and protracted stroke risk.Further study is required to elucidate the mechanisms of long-term increased stroke risk after TBI. | Morris NA Cool J Merkler AE Kamel H | 2017 | 中华神经外科疾病研究杂志2017，16，4： | 6 |
| 2 | Dietary zinc and metallothionein on small intestinal disaccharidases activity in mice显示文摘AIM: To examine the effect of increasing dietary zinc (Zn) intake and the lack of metallothionein (MT) expression on activity of small intestinal disaccharidases. METHODS: MT-Ⅰ and Ⅱ knockout (MT-/-) and wild-type (MT+/+) female mice at 3.5 wk of age were randomly fed with a diet containing 2 (2 Zn), 15 (15 Zn) or 50 (50 Zn) mg Zn/kg (n = 8/group/genotype) for 5 wk. Small intestinal segments (duodenum, jejunum and ileum) were collected and either fixed in 10% formalin for histological analysis or snap frozen in liquid nitrogen for sucrase, lactase and maltase activity analyses.RESULTS: Plasma Zn was significantly (P < 0.05) lower (33%) in MT-/- compared with MT+/+ mice fed the 2 Zn diet. Villus height and crypt depth were increased by approximately 15% in MT+/+ mice compared with MT-/- mice. Duodenal disaccharidase activities were significantly higher in MT+/+ compared with MT-/- mice particularly in those fed the 2 Zn diet. For the 50 Zn diet, jejunal sucrase and lactase activities were significantly higher in MT-/- (13 313 ± 2314; 4107 ± 364 μmol glucose/well/min/g tissue, respectively) compared with MT+/+ mice (7054 ± 608; 1818 ± 174). Similarly, ileal lactase activities were higher in MT-/- (1480 ± 192) compared with MT+/+ (629 ± 353) mice particularly those fed the 2 Zn diet. CONCLUSION: Increasing dietary Zn has little effect on disaccharidases activity in MT wild-type mice. The presence of MT may enhance morphological and functional development of the gut. | Cuong D Tran Johanna Cool Cory J Xian | 2011 | World Journal of Gastroenterology2011，17，3： | 2 |
| 3 | Relationships between Categories of Relevance Criteria and Stage in Task Completion显示文摘 | Taylor A R Cool C Belkin N J | 2007 | Information Processing and Management2007，43，4： | 1 |
| 4 | Pre-treatment of cucumber plants with acibenzolar-S-methyl systemically primes a phenylalanine ammonia lyase gene (PAL1) for enhanced expression upon attack with a pathogenic fungus显示文摘 | Cools H J Ishii H | 2002 | Physiological and Molecular Plant Pathology2002，61，5： | 1 |
| 5 | A nonmosaic 45,X karyotype in a mother with Turner's syndrome and in her daughter显示文摘 | COOLS M ROOMAN R P WAUTERS J | 2004 | Fertil Steril2004，82，4： | 1 |
| 6 | Fluoroquinolone treatment of experimental Salmonella enterica serovarTyphimurium DT104 infections in chickens selects for both gyrA mutations and changes in efflux pump gene expression CJ3显示文摘 | Randall L P Eaves D J Cooles S W | 2005 | J Antimicrob Chemother2005，56，2： | 1 |
| 7 | The role of intedankin-4 in the regulation of mouse primordial germ cell numbers 显示文摘 | Coole J E Heasman J and Wylie C C | 1996 | Dev Biol1996，174，： | 1 |
| 8 | Identification of novelfusion partners of ALK, the anaplastic lymphoma kinase,in anaplastic large-cell lymphoma and inflammatory myofbroblastictumor显示文摘 | Cools J W lodarska I Somers R | 2002 | Genes Chromosomes Cancer2002，34，4： | 1 |
| 9 | Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis显示文摘 | Levine RL Wadleigh M Cools J | 2005 | Cancer Cell2005，7，4： | 1 |
| 10 | Acute interstitial pneumonitis: case series and review of the literature 显示文摘 | Vourlekis J S Brown K K Cool C D | 2000 | Medicine2000，79，6： | 1 |
| 11 | A tyrosine kinase created by fusion of the PDGRFRA and FIP1L1 genes as a thera- peutic target of imatinib in idiopathic hy- pereosinophilic syndrome 显示文摘 | Cools J DeAngelo D J Gotlib J | 2003 | N Engl J Med2003，348，13： | 1 |
| 12 | Design Principles of Help Systems for Digital Libraries 显示文摘 | Perez - Carballo J Xie I Cool C | 2011 | Academy of Information and Management Sciences Journal2011，，1： | 1 |
| 13 | Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants 显示文摘 | Henderson-Smart D J Cools F Bhuta T | 2007 | Cochrane Database Syst Rev2007，18，00： | 1 |
| 14 | Flupyrsulfuron soil dissipation and mobility in winter wheat crops显示文摘 | Rouchaud J Neus O Cools K | 1999 | J Agri Food Chem1999，47，： | 1 |
| 15 | Role of ascospores in further spread of QoI-resistant cytochrome balleles (G143A) in field populations of Mycosphaerella graminicola显示文摘 | Fraaije B A Cools H J Fountaine J | 2005 | Phytopathology2005，95，8： | 1 |
| 16 | Activating Mutation in the Tyrosine Kinase JAK2 in Polycythemia Vera, Essential Thrombocythemia,and Myeloid Metaplasia with MycloSibrosis 显示文摘 | Levine R L Wadleigh M Cools J | 2005 | Cancer Cell2005，7，4： | 1 |
| 17 | Survivable LANs for distributed control systems显示文摘 | Cooling J E | 1994 | Computer Communications1994，17，5： | 1 |
| 18 | Activating mutation in the tyrosine kinase JAN2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis显示文摘 | LEVINE R L WADLEIGH M COOLS J | 2005 | Cancer Cell2005，7，： | 1 |
| 19 | Activating mutation in the tyrosine kinase JAK2 in polycythemia vera,essential thrombocythemia,and myeloid metaplasia with myelofibrosis显示文摘 | Levine RL Wadleigh M Cools J | 2005 | Cancer Cell2005，7，4： | 1 |
| 20 | Filum terminale lipomas : imaging prevalence, natural history, and conus position显示文摘 | Cools M J A1-Holou WN Stetler WR | 2014 | J Neurosurg Pediatr2014，13，5： | 1 |
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