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| 1 | Acute upper gastrointestinal bleeding in operated stomach: Outcome of 105 cases显示文摘AIM: To compare the causes and clinical outcome of patients with acute upper gastrointestinal bleeding (AUGB) and a history of gastric surgery to those with AUGB but without a history of gastric surgery in the past.METHODS: The causes and clinical outcome were compared between 105 patients with AUGB and a history of gastric surgery, and 608 patients with AUGB but without a history of gastric surgery.RESULTS: Patients who underwent gastric surgery in the past were older (mean age: 68.1±11.7 years vs 62.8±17.8 years, P= 0.001), and the most common cause of bleeding was marginal ulcer in 63 patients (60%). No identifiable source of bleeding could be found in 22 patients (20.9%) compared to 42/608 (6.9%) in patients without a history of gastric surgery (P = 0.003). Endoscopic hemostasis was permanently successful in 26 out of 35 patients (74.3%) with peptic ulcers and active bleeding or non-bleeding visible vessel. Nine patients (8.6%) were operated due to continuing or recurrent bleeding,compared to 23/608 (3.8%) in the group of patients without gastric surgery in the past (P= 0.028). Especially in peptic ulcer bleeding patients, emergency surgery was more common in the group of patients with gastric surgery in the past [9/73 (12.3%) vs 19/360 (5.3%), P = 0.025].Moreover surgically treated patients in the past required more blood transfusion (3.3±4.0 vs 1.5±1.7, P = 0.0001) and longer hospitalization time (8.6±4.0 vs 6.9±4.9 d,P = 0.001) than patients without a history of gastric surgery. Mortality was not different between the two groups [4/105 (3.8%) vs 19/608 (3.1%)].CONCLUSION: Upper gastrointestinal bleeding seems to be more severe in surgically treated patients than in non-operated patients. | Vassiliki N Nikolopoulou Konstantinos C Thomopoulos George I Theocharis Vassiliki A Arvaniti Constantine E Vagianos | 2005 | World Journal of Gastroenterology2005,11,29: | 9 |
| 2 | Role of advanced magnetic resonance imaging in the assessment of malignancies of the mediastinum显示文摘In the new era of functional magnetic resonance imaging(MRI), the utility of chest MRI is increasing exponentially due to several advances, including absence of ionizing radiation, excellent tissue contrast and high capability for lesion characterization and treatment monitoring. The application of several of these diagnostic weapons in a multiparametric fashion enables to better characterize thymic epithelial tumors and other mediastinal tumoral lesions, accurate assessment of the invasion of adjacent structures and detection of pathologic lymph nodes and metastasis. Also, 'do not touch lesions' could be identified with the associated impact in the management of those patients. One of the hotspots of the multiparametric chest MR is its ability to detect with acuity early response to treatment in patients with mediastinal malignant neoplasms. This has been related with higher rates of overall survival and progression free survival.Therefore, in this review we will analyze the current functional imaging techniques available(18 F-Fluorodeoxiglucose positron emission tomography/computed tomography, diffusion-weighted imaging, dynamic contrast-enhanced MRI, diffusion tensor imaging and MR spectroscopy) for the evaluation of mediastinal lesions, with a focus in their correct acquisition and post-processing. Also, to review the clinical applications of these techniques in the diagnostic approach of benign and malignant conditions of the mediastinum. | Jordi Broncano Ana María Alvarado-Benavides Sanjeev Bhalla Antonio álvarez-Kindelan Constantine A Raptis Antonio Luna | 2019 | World Journal of Radiology2019,11,3: | 4 |
| 3 | Correlation between the proportion of breast volume involved by locally advanced tumors and invasion of the skin and posterior structures显示文摘AIM: To evaluate any differences between the percentages of involved breast volume, pathologic attributes,and tumor marker expression of T3 and T4a-c tumors in locally advanced breast cancers(BC).METHODS: All patients with T3 N > 0 and T4a-c BC without evidence of distant metastasis(M0), presenting to the Breast Clinic from 1980 to 2010, were examinedto determine whether their BC's involved ≥ 50% of their breast volumes, defined by gross replacement of at least one hemisphere. Core needle biopsy or postmastectomy specimens from tumors involving a known percent of breast volume were evaluated for:(1)pathological grades and lympho-vascular invasion(LVI);(2) hormone receptor(ER/PR) expression > 0; and(3)epidermoid growth factor 2(her2) over-expression(3+)by immune-histochemical staining or fluorescent in situ hybridization.RESULTS: The data base included 98 patients with T3N> 0 M0 and 120 with T4a-c, any N disease, M0 disease. T3 tumor masses involved 50% or more of the breast in 23/98(24%), and T4a-c tumors 65/120(54%)(P < 0.001). Only 1% of T3 tumors and 23% of T4a-c tumors presented with total breast replacement. There were no significant differences between the pathological attributes and marker expression of the T3 and T4a-c tumors.CONCLUSION: These data suggest that erosion of the overlying skin or underlying chest wall by some BC may be due to neglect and delay, rather than inherent biological aggressiveness. | Parastoo B Dahi Komal P Dhiran Constantine A Axiotis Jeremy Weedon Mahmoud El-Tamer Gurinder Sidhu Albert S Braverman | 2012 | World Journal of Clinical Oncology2012,3,3: | 2 |
| 4 | Formation of strong fronts in the 2-D quasi-geostrophic thermal active scalar显示文摘 | Constantin P Majda A Tabak E | 1994 | Nonlinearity1994,7,6: | 1 |
| 5 | Stability of a class of solitary waves in compressible elastic rod显示文摘 | CONSTANTIN A STRAUSS W A | 2000 | Physics Letters A2000,270,: | 1 |
| 6 | Scissor-jack-damper Energy Dissipation System 显示文摘 | Sigaher A N Constantinou M C | 2003 | Earthquake Spectra2003,19,1: | 1 |
| 7 | Sliding Isolation System for Bridges:Experimental Study显示文摘 | Constantinou M C Kartoum A | 1992 | Earthquake Spectra1992,8,3: | 1 |
| 8 | Variation in Echinococcus: towards a taxonomic revision of the genus 显示文摘 | Thompson R C A Lymbery A J Constantine C C | 1995 | Adv Parasitol1995,35,: | 1 |
| 9 | Cancer-associated myositis:clinical features and prognostic signs显示文摘 | Ponyi A Constantin T Garami M | 2005 | Annals of the NewYork Academy of Science2005,1051,: | 1 |
| 10 | Well-posedness, global existence and blow-up phenomena for a periodic quasi-linear hyperbolic equation显示文摘 | Constantin A Escher J | 1998 | Comm Pure Appl Math1998,51,: | 1 |
| 11 | On the scattering problem for the Camassa-Holm equation显示文摘 | Constantin A | 2001 | Proceedings of The Royal Society A2001,457,2008: | 1 |
| 12 | National registry of patients with juvenile idiopathic inflammatory myopa- thies in Hungary--clinical characteristics and disease course of 44 patients with juvenile dermatomyositis 显示文摘 | Constantin T Ponyi A Orban I | 2006 | Autoimmunity2006,39,3: | 1 |
| 13 | Sesmic Isolation Retrofit of Large Historic Buildings显示文摘 | Mokha A S Amin N Constantinou M C | 1996 | Journal of structure engineering ASCE1996,122,3: | 1 |
| 14 | Isolation of isoflavones from soy-based fermentations of the erythromycin-producing bacterium Saccharopolyspora erythraea显示文摘 | HESSLER P E LARSEN P E CONSTANTINOU A I | 1997 | Appl Microbiol Biotechnol1997,47,4: | 1 |
| 15 | Abatacept therapyand safety management显示文摘 | Pham T Claudepierre P Constantin A | 2009 | Joint Bone Spine2009,76,: | 1 |
| 16 | Global existence and blow-up for a shallow water equation显示文摘 | Constantin A Escher J | 1998 | Ann Scuola Norm SUP Pisacl Sci1998,26,4: | 1 |
| 17 | Seismic isolation retrofit of large historic building显示文摘 | Mokha A S Amin N Constantinou M C Zayas V | 1996 | Journal of Structural Engineering ASCE1996,122,3: | 1 |
| 18 | Effects of activated charcoal on callus growth and shoot organo genesis in tobacco显示文摘 | CONSTANTIN M J HENKE R R MANSUR M A | 1977 | In Vitro1977,13,5: | 1 |
| 19 | Sliding Isolation System for Bridges : Experimental Study 显示文摘 | Constantinou M C Kartoum A Reihorn A M | 1992 | Earthquake Spectra1992,8,3: | 1 |
| 20 | Conservative vs restrictive individualized goal-directed fluid replacement strategy in major ab dominal surgery:A prospective randomized trial显示文摘 | Futier E Constantin JM Petit A | | 0,,12: | 1 |