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| 1 | Concordance among indices of intrinsic brain function: Insights from inter-individual variation and temporal dynamics显示文摘Various resting-state fMRI(R-fMRI) measures have been developed to characterize intrinsic brain activity. While each of these measures has gained a growing presence in the literature, questions remain regarding the common and unique aspects these indices capture. The present work provided a comprehensive examination of inter-individual variation and intra-individual temporal variation for commonly used measures, including fractional amplitude of low frequency fluctuations, regional homogeneity,voxel-mirrored homotopic connectivity, network centrality and global signal correlation. Regardless of whether examining intra-individual or inter-individual variation, we found that these definitionally distinct R-fMRI indices tend to exhibit a relatively high degree of covariation, which doesn't exist in phase randomized surrogate data. As a measure of intrinsic brain function, concordance for R-fMRI indices was negatively correlated with age across individuals(i.e., concordance among functional indices decreased with age). To understand the functional significance of concordance, we noted that higher concordance was generally associated with higher strengths of R-fMRI indices, regardless of whether looking through the lens of inter-individual(i.e., high vs. low concordance participants) or intra-individual(i.e., high vs.low concordance states identified via temporal dynamic analyses) differences. We also noted a linear increase in functional concordance together with the R-fMRI indices through the scan, which may suggest a decrease in arousal. The current study demonstrated an enriched picture regarding the relationship among the R-fMRI indices, as well as provided new insights in examining dynamic states within and between individuals. | Chao-Gan Yan Zhen Yang Stanley J. Colcombe Xi-Nian Zuo Michael P. Milham | 2017 | Science Bulletin2017，62，23： | 13 |
| 2 | Aerobic fitness reduces brain tissue loss in aging humans显示文摘 | COLCOMBE S J ERICKSON K I RAZ N | 2003 | J Gerontol A Biol Sci Med Sci2003，58，2： | 1 |
| 3 | Fitness effects on the cognitive function of older adults A meta-analytic study显示文摘 | COLCOMBE S KRAMER A F | 2003 | Psychological Science2003，14，2： | 1 |
| 4 | Cardiovascular fitness, cor- tical plasticity and aging 显示文摘 | Colcombe Kramer Erickson | 2004 | Proceedings of the National Academy of Sciences of the United States of America2004，101，9： | 1 |
| 5 | Aerobic fitness reduces brain tissue loss in aging humans显示文摘 | COLCOMBE S J ERICKSON K I RAZ N | 2003 | J Gerontol A Biol Sei Med Sci2003，58，2： | 1 |
| 6 | Exercise,cognition,and the aging brain显示文摘 | Kramer AF Erickson KI Colcombe SJ | | 0，，： | 1 |
| 7 | Fitness effects on the cognitive function of older adults: a meta-analytic study显示文摘 | Colcombe S Kramer A F | 2003 | Psychol Sci2003，14，2： | 1 |
| 8 | Aerobic fitness reduces brain tissue loss in aging humans 显示文摘 | Colcombe SJ Erickson KI Raz N | 2003 | J Gerontol A Biol Sci Med Sci2003，58，2： | 1 |
| 9 | Aerobic exercise training increases brain volume in aging humans显示文摘 | Colcombe S J Erickson KI Scalf P Kim J Prakash R McAuley E | | 0，，： | 1 |
| 10 | Aerobic exer- cise training increases brain volume in aging humans显示文摘 | Colcombe SJ Erickson KI Scalf PE | 2006 | J Gerontol A Biol Sci Med Sci2006，61，11： | 1 |
| 11 | Fitness effects on the cognitive function of older adults : a meta - analytic study 显示文摘 | Colcombe S Kramer A F | 2003 | Psy- chological Science2003，14，2： | 1 |
| 12 | Cardiovascular fitness and neurocognitive function in older adults: a brief review显示文摘 | McAuley E Kramer AF Colcombe SJ | 2004 | Brain Behav Immun2004，18，3： | 1 |
| 13 | Cardiovas- cular fitness, cortical plasticity, and aging显示文摘 | Colcombe SJ Kramer AF Erickson KI | 2004 | Proc Nati Acad Sci2004，101，9： | 1 |
| 14 | Aerobic fitness reduCes brain tissue loss in aging humans显示文摘 | Colcombe S J Eriekson K I Raz N | 2003 | The Journals of Gerontology Series A : Biological Sciences and Medical Sciences2003，58，2： | 1 |
| 15 | Fitness effects on the cognitive function of older adults:a meta-analytic study显示文摘 | Colcombe SJ Kramer AF | | 0，，： | 1 |
| 16 | Training-inducedplasticity in older adults: effects of training on hemisphericasymmetry显示文摘 | Erickson KI Colcombe SJ Wadhwa R | 2007 | Neurobiol Aging2007，28，2： | 1 |
| 17 | Aerobic exercise training increases brain volume in aging humans显示文摘 | COLCOMBE S J ERICKSON K I SCALF P E | 2006 | J Gerontol A Biol Sei Med Sei2006，61，11： | 1 |
| 18 | Fitness effects on the cognitive function of older adults: a meta-analytic study显示文摘 | Colcombe S Kramer AF | 2003 | Psychol Sci2003，14，2： | 1 |
| 19 | The implications of cortical recruitment and brain morphology for individual differences in inhibitory function in aging humans显示文摘 | Colcombe SJ Kramer AF Erickson KI | 2005 | Psychol Aging2005，20，3： | 1 |
| 20 | Aerobic Exercise Training Increases Brain Volume in Aging Hu- mans显示文摘 | COLCOMBE S J ERICKSON K I SCALF P E | 2006 | J Gerontol ABiolSci MedSci2006，61，11： | 1 |
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