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26篇 您的检索式：作者名="Colagrande L"

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	题名	作者	年代	出处	被引量
1	challenges of advanced hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is an aggressive malignancy,resulting as the third cause of death by cancer each year. The management of patients with HCC is complex,as both the tumour stage and any underlying liver disease must be considered conjointly. Although surveillance by imaging,clinical and biochemical parameters is routinely performed,a lot of patients suffering from cirrhosis have an advanced stage HCC at the first diagnosis. Advanced stage HCC includes heterogeneous groups of patients with different clinical condition and radiological features and sorafenib is the only approved treatment according to Barcelona Clinic Liver Cancer. Since the introduction of sorafenib in clinical practice,several phase Ⅲ clinical trials have failed to demonstrate any superiority over sorafenib in the frontline setting. Locoregional therapies have also been tested as first line treatment,but their role in advanced HCC is still matter of debate. No single agent or combination therapies have been shown to impact outcomes after sorafenib failure. Therefore this review will focus on the range of experimental therapeutics for patients with advanced HCC and highlights the successes and failures of these treatments as well as areas for future development. Specifics such as dose limiting toxicity and safety profile in patients with liver dysfunction related to the underlying chronic liver disease should be considered when developing therapies in HCC. Finally,robust validated and reproducible surrogate end-points as well as predictive biomarkers should be defined in future randomized trials.	Stefano Colagrande Andrea L Inghilesi Sami Aburas Gian G Taliani Cosimo Nardi Fabio Marra	2016	World Journal of Gastroenterology2016，22，34：	19
2	Extracorporeal membrane oxy- genation to support adult patients with cardiac failure:predictive factors of 30-day mortality 显示文摘	Formica F Avalli L Colagrande L	2010	Interact Cardiovasc Thorac Surg2010，10，5：	1
3	Solitary necrotic nodule of the liver: imaging and correlation with pathologic features显示文摘	Colagrande S Politi LS Messerini L	2003	Abdom Imaging2003，28，1：	1
4	Solitary necrotic noldule of the liver:imaging and correlation with pathologic features显示文摘	Colagrande S Politi L S Messerini L	2003	Abdom Imaging2003，28，1：	1
5	Extracorporeal membraneoxygenation to support adult patients with cardiac failure :predictive factors of 30-day mortality 显示文摘	Formica F Avalli L Colagrande L	2010	Interact CardiovascThorac Surg2010，10，5：	1
6	Solitary necrotic nodule of the liver: imaging and correlation with pathologic features 显示文摘	Colagrande S Politi LS Messerini L	2003	Abdom Imaging2003，28，1：	1
7	Meaning and etiopathogenesis of sectorial transient hepatic attenuation differences (THAD)显示文摘	Colagrande S Centi N Carmignani L	2003	Radiol Med (Torino)2003，105，3：	1
8	Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis显示文摘	Rolla G Brussino L Colagrande P	1997	Hepatology1997，26，：	1
9	Transient hepatic attenuation difference (THAD) not connected to focal lesions显示文摘	Colagrande S Carmignani L Pagliari A	2002	Radiat Med2002，104，12：	1
10	Solitary, necrotic nodule of the liver:imag ng and correlation with pathologic features显示文摘	Colagrande S Politi E S Messerini L	2003	Abdomhnaging2003，28，1：	1
11	The early outcome in patients undergoing off-pump coronary artery bypass grafting: our experience显示文摘	Gianoli M Formica F Ferro O Colagrande L Gastaldi D Chiodini P	2005	Ital Heart J2005，6，：	1
12	Exhaled nitric oxide and impaired oxygenation in cirrhotic patients before and after liver transplantation显示文摘	Rolla G1 Brassino L Colagrande P	1998	Ann Intern Med1998，1129，5：	1
13	Solitary necrotic nodule of the liver显示文摘	Colagrande S Politi LS messerini L	2003	Abdom Imaging2003，28，1：	1
14	Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis显示文摘	Brussino L Colagrande P	1997	Hepatology1997，26，4：	1
15	Exhaled nitric oxide and impaired oxygenation in cirrhotic patients before and after liver transplantation显示文摘	Brussino L Colagrande P	1998	Ann Inter Med1998，129，5：	1
16	Exhaled nitric oxide and impaired oxygenation in cirrhotic patients before and after liver transplantation显示文摘	Rolla G Brussino L Colagrande P	1998	Ann Intern Med1998，129，5：	1
17	Solitary necrotic nodule of the liver:imaging and correlation with pathologic features显示文摘	Colagrande S Politi LS Messerini L	2003	Abdom Imaging2003，28，1：	1
18	Exhaled nitric oxide and impaired oxygenation in cirrhotic patients before and after liver transplantation显示文摘	Rolla G Bmssino L Colagrande P	1998	Ann Intern Med1998，129，5：	1
19	Reduced cytokines release and myocardial damage in coronary artery bypass patients due to L-arginine cardioplegia supplementation显示文摘	Colagrande L Formica F Porta F	2006	Ann Thorac Surg2006，81，4：	1
20	Meaning and etiopathogenesis of sectorial transient hepatic attenuation differences (THAD) 显示文摘	Colagrande S Centi N Carmignani L	2003	Radiol Med (Torrino)2003，105，3：	1

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