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75篇 您的检索式:作者名="Cognet"
    题名 作者 年代 出处 被引量
1In Vivo Therapeutic Silencing of Hypoxia-Inducible Factor 1 Alpha(HIF-1)Using Single-Walled Carbon Nanotubes Noncovalently Coated with siRNA显示文摘A new approach is described for delivering small interfering RNA(siRNA)into cancer cells by noncovalently complexing unmodifi ed siRNA with pristine single-walled carbon nanotubes(SWCNTs).The complexes were prepared by simple sonication of pristine SWCNTs in a solution of siRNA,which then served both as the cargo and as the suspending agent for the SWCNTs.When complexes containing siRNA targeted to hypoxia-inducible factor 1 alpha(HIF-1)were added to cells growing in serum containing culture media,there was strong specific inhibition of cellular HIF-1 activity.The ability to obtain a biological response to SWCNT/siRNA complexes was seen in a wide variety of cancer cell types.Moreover,intratumoral administration of SWCNT-HIF-1 siRNA complexes in mice bearing MiaPaCa-2/HRE tumors signifi cantly inhibited the activity of tumor HIF-1.As elevated levels of HIF-1 are found in many human cancers and are associated with resistance to therapy and decreased patient survival,these results imply that SWCNT/siRNA complexes may have value as therapeutic agents.Geoffrey Bartholomeusz Paul Cherukuri John Kingston Laurent Cognet Robert Lemos Jr Tonya KLeeuw Laura Gumbiner-Russo RBruce Weisman Garth Powis 2009Nano Research2009,2,4:7
2Epiphyseal tibial osteoblastoma:report of a rare localization and review of the literature显示文摘Ehlinger M Cognet J M Chiffolot X 2003Rev Chir Orthop Reparatrice Appar Mot2003,89,3:1
3Neutrophil depletion impairs natural killer cell maturation,function,and homeostasis显示文摘Jaeger BN Donadieu J Cognet C 2012J Exp Med2012,209,3:1
4Perineural ultrasound-guided catheter bacterial Colonization: a prospective evaluation in 747 eases显示文摘Aveline Christophe Le Hetet Hubert Le Roux Alain Vautier Pierre Gautier Jean Fran~ois Cognet Fabrice Auger Philippe Bonnet Francis 2011Regional Anesthesia and Pain Medicine2011,36,6:1
5Treatment of femoral fracture on pre-vious implants with minimally - invasive surgery and total weight - bear-ing :benefit of locking plate 显示文摘Ehlinger M Cognet JM Simon P 2008Rev Chir Orthop Reparatrice ApparMot2008,94,1:1
6Electro- chemical determination of ferrocene diffusion coeffi- cient in liquid media under high CO2 pressure: Appli- cation to DMF-CO2 mixtures 显示文摘CHANFREAU S COGNET P CAMY S et M 2007J Electroanalytical Chemistry2007,604,:1
7Clean synthesis ofadipic acid from cyclohexene in microemulsions with stearyl dimethyl benzyl ammonium chloride as surfactant: From the laboratory to benchscale显示文摘Penate I Q Lesage G Cognet P 2012Chemical Engineering Journal2012,,:1
8Treatment of femoral fracture on previous implants with minimally-invasive surgery and total weight-bearing:benefit of locking plate显示文摘Ehlinger M Cognet JM Simon P 0,,01:1
9Ultrasound in organic electrosynthesis显示文摘 WILHELM A M DELMAS H 2000Ultrasonics Sonochemistry2000,7,4:1
10Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis 显示文摘Kuhlmann T Remington L Cognet I 2006Am J Pathol2006,169,2:1
11Treatment of femoral fracture on previous implants with minimally ~invasive surgery and total weight~bearing:benefit of locking plate显示文摘Ehlinger M Cognet JM Simon P 0,,01:1
12A role for interleukin-12/23 in the maturation of human natural killer and CD56^+ T cells in vivo 显示文摘Guia S Cognet C de Beaucoudrey L 2008Blood2008,111,10:1
13Anatomical basis for distal sartorius muscle flap for reconstructive surgery below the knee anatomical study andcasereport显示文摘Clavert P Cognet JM Baley S 2008J Plast Reconstr Aesthet Surg2008,61,1:1
14Stoichio-kinetic modeling and optimization of chemical synthesis: Application to the aldolic condensation of furfural on acetone 显示文摘FAKHFAKH N COGNET P CABASSUD M LUCCHESE Y RIOIOS M D D L 2008Chem Eng Process2008,47,3:1
15Epiphyseal tibial osteoblastoma: report of a rare localization and review of the literature显示文摘Ehlinger M Cognet JM Chiffolot X 2003Rev Orthop Reparatrice Appar Mot2003,89,:1
16Application of an electrochemical pulsed flow reactor to electroorganic synthesis:Part Ⅰ:Reduction of acetophenone显示文摘Belmant C Cognet P Bbrlan J 1998Journal of Applied Electrochemistry1998,28,2:1
17Treatment of femoral fracture on previous implants with minimally-invasive surgery and total weight-bearing: benefit of locking plate显示文摘Eblinger M Cognet JM Simon P 2008Rev Chir Orthop Reparatrice Appar Mot2008,94,1:1
18Treatment of femoral fracture onprevious implants with minimally-invasive surgery and total weight-bearing:benefit of locking plate显示文摘Ehlinger M Cognet JM Simon P 2008Rev Chir Orthop ReparatriceAppar Mot2008,94,1:1
19Chronic mesenter ic ischcmia: imaging andpercutaneous treatment 显示文摘Cognet F Ben-Salem D Dr ans sart M et ai 2002Radiographies2002,22,4:1
20Treatment of femoral fracture on previous implants with minimally-invasive surgery and total weight-bearing:benefit of locking plate显示文摘Ehlinger M Cognet JM Simon P 2008Rev Chir Orthop Reparatrice Appar Mot2008,94,1:1
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