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7篇 您的检索式:作者名="Clements KE"
    题名 作者 年代 出处 被引量
1Combined high-resolution genotyping and geospatial analysis reveals modes of endemic urban typhoid fever transmission显示文摘Baker S Holt KE Clements ACA 2011Open Biol2011,1,11:1
2Immunohistochemical assessment of the neurosecretory cells of the chicken thymus using a novel monoclonal antibody against avian chromogranin A显示文摘Oubre CM Zhang X Clements KE 2004Dev Comp Immunol2004,28,4:1
3Nonoperative management of displaced olecranon fractures in low - de- mand elderly patients 显示文摘Duckworth AD Bugler KE Clement ND 2014J Bone Joint Surg Am2014,96,1:1
4Measuring func- tional improvement after total knee arthroplasty requires both per-formance-based and patient-report assessments: a longitudinal analysis of outcomes 显示文摘Mizner RL Petterson SC Clements KE 2011J Arthroplasty2011,26,5:1
5Organization of glutamatelike immunoreactivity in the rat superficial dorsal horn:Light and electron microscopic observations显示文摘Miller KE Clements JR Larson AA 0,,01:1
6Evaluation of the association of C5 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy显示文摘Background:Neovascular age-related macular degeneration(AMD)and polypoidal choroidal vasculopathy(PCV)are sight-threatening maculopathies with both environmental and genetic risk factors.We have previously shown relative risks posed by genes of the complement pathways to neovascular AMD and PCV.Methods:In this study,we investigated the haplotype-tagging single nucleotide polymorphisms(SNPs)in the complement component 5(C5)gene in 708 unrelated Chinese individuals:200 neovascular AMD patients,233 PCV patients and 275 controls.Six tagging SNPs in C5 were genotyped.Univariate single SNP association analysis,haplotype-based association analysis and gene-gene interaction analysis between C5 and other AMD-associated genes were performed.Results:The results revealed none of the six tagging SNPs of the C5 gene had a significant association with neovascular AMD or PCV(P>0.05).We also found insignificant haplotype-based association,and no significant SNPSNP interaction between C5 and other genes(including C2-CFB-RDBP-SKIV2L,SERPING1,CETP,ABCG1,PGF,ANGPT2,CFH and HTRA1)for neovascular AMD and PCV.Conclusions:This study showed no statistical significance in the genetic association of C5 with neovascular AMD or PCV in a Hong Kong Chinese population.Further studies in large samples from different populations are warranted to elucidate the role of C5 in the genetic susceptibility of AMD and PCV.Ke Liu Li Ma Timothy Y.Y.Lai Marten E.Brelen Pancy O.S.Tam Clement C.Tham Chi Pui Pang Li Jia Chen 2019Eye and Vision2019,6,1:1
7Femoral neck trabecular bone:loss with aging and role ?n preventing fracture显示文摘Thomas CD Mayhew PM Power J Poole KE Loveridge N Clement JG Burgoyne Q Reeve J 0,,:1
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