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| 1 | Anti-TNF alpha in the treatment of ulcerative colitis:A valid approach for organ-sparing or an expensive option to delay surgery?显示文摘Ulcerative colitis(UC)is an inflammatory bowel disease affecting large bowel with variable clinical course.The history of disease has been modified by the introduction of biologic therapy,in particular Infliximab(IFX),that has demonstrated efficacy in inducing fast symptoms remission,promoting mucosal healing and maintaining long-term remission.However,surgery is still needed for UC patients:in case of failure of medical therapy and if acute complications or a malignancy occurred.Surgical treatment is associated with a short-term postoperative mortality and morbidity respectively of 0%-4%and 30%.In this study we systematically analyzed:the role of IFX in reducing the colectomy rate,the risk of post-operative morbidity in pre-operatively IFX-treated patients and the cost-effectiveness of IFX therapy.Four of 5 analyzed randomized controlled trials demonstrated that therapy with IFX significantly reduces the colectomy rate.Moreover,pre-operative treatment with IFX doesn’t seem to increase post-operative infectious complications.By an economic point of view,the cost-effectiveness of IFX-therapy was demonstrated for UC patients suffering from moderate to severe UC in a study based on a cost estimation of the National Health Service of England and Wales.However,the argument is debated. | Gianluca Rizzo Daniela Pugliese Alessandro Armuzzi Claudio Coco | 2014 | World Journal of Gastroenterology2014，20，17： | 5 |
| 2 | Stapled Hemorrhoidopexy and Milligan Morgan Hemorrhoidectomy in the Cure of Fourth-Degree Hemorrhoids: Long-Term Evaluation and Clinical Results显示文摘 | Claudio Mattana M.D. Claudio Coco M.D. Alberto Manno M.D. Alessandro Verbo M.D. Gianluca Rizzo M.D. Luigi Petito M.D. Daniel Sermoneta M.D | 2007 | Diseases of the Colon & Rectum2007，，11： | 1 |
| 3 | Prognostic Value of Pathologic Complete Response After Neoadjuvant Therapy in Locally Advanced Rectal Cancer: Long-Term Analysis of 566 ypCR Patients显示文摘 | Carlo Capirci Vincenzo Valentini Luca Cionini Antonino De Paoli Claus Rodel Robert Glynne-Jones Claudio Coco Mario Romano Giovanna Mantello Silvia Palazzi Falchetti Osti Mattia Maria Luisa Friso Domenico Genovesi Cristiana Vidali Maria Antonietta Gambacor | 2008 | International Journal of Radiation Oncology Biology Physics2008，，1： | 1 |
| 4 | Isolated fetal pyelectasis and chromosomal abnormalities 显示文摘 | Coco Claudio Jeanty Philippe | 2005 | Am J Obstet Gynecol2005，193，： | 1 |
| 5 | Stapled Hemorrhoidopexy and Milligan Morgan Hemorrhoidectomy in the Cure of Fourth-Degree Hemorrhoids: Long-Term Evaluation and Clinical Results显示文摘 | Claudio Mattana M.D. Claudio Coco M.D. Alberto Manno M.D. Alessandro Verbo M.D. Gianluca Rizzo M.D. Luigi Petito M.D. Daniel Sermoneta M.D | 2007 | Diseases of the Colon & Rectum2007，，11： | 1 |
| 6 | The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer显示文摘 | Fabio Maria Vecchio Vincenzo Valentini Bruce D. Minsky Gilbert D.A. Padula Ennapadam S. Venkatraman Mario Balducci Francesco Miccichè Riccardo Ricci Alessio Giuseppe Morganti Maria Antonietta Gambacorta Francesca Maurizi Claudio Coco | 2005 | International Journal of Radiation Oncology Biology Physics2005，，3： | 1 |
| 7 | The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer显示文摘 | Fabio Maria Vecchio Vincenzo Valentini Bruce D. Minsky Gilbert D.A. Padula Ennapadam S. Venkatraman Mario Balducci Francesco Miccichè Riccardo Ricci Alessio Giuseppe Morganti Maria Antonietta Gambacorta Francesca Maurizi Claudio Coco | 2005 | International Journal of Radiation Oncology, Biology, Physics2005，，3： | 1 |
| 8 | 听海的声音 东京le salon专卖店显示文摘克劳迪·克鲁奇(Claudio Colucc)i,1965年出生于瑞士Locarno,著名工业设计师、室内设计师,先后毕业于日内瓦装饰艺术学院以及巴黎法国国立高等设计学院。回到巴黎之后,追随法国设计大师Philippe Starck从事设计创作。1994年与四位业界同好创立"巴黎工业设计自动生产研究派",并于2000年获得巴黎家居沙龙展年度设计师荣誉。 | Claudio Colucci COCO | 2011 | 室内设计与装修2011，，9： | 0 |
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