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| 1 | Prognostic value of increased carbohydrate antigen in patients with heart failure显示文摘AIM:To study the prognostic value of carbohydrateantigen 125(CA125) and whether it adds prognostic information to N-terminal pro-brain natriuretic peptide(NT-proBNP) in stable heart failure(HF) patients.METHODS:The predictive value of CA125 was retrospectively assessed in 156 patients with stable HF remitted to the outpatient HF unit for monitoring from 2009 to 2011.Patients were included in the study if they had a previous documented episode of HF and received HF treatment.CA125 and NT-proBNP concentrations were measured.The independent association between NT-proBNP or CA125 and mortality was assessed with Cox regression analysis,and their combined predictive ability was tested by the integrated discrimination improvement(IDI) index.RESULTS:The mean age of the 156 patients was 72 ± 12 years.During follow-up(17 ± 8 mo),27 patients died,1 received an urgent heart transplantation and 106 required hospitalization for HF.Higher CA125 values were correlated with outcomes:58 ± 85 KU/L if hospitalized vs 34 ± 61 KU/L if not(P < 0.05),and 94 ± 121 KU/L in those who died or needed urgent heart transplantation vs 45 ± 78 KU/L in survivors(P < 0.01).After adjusting for propensity scores,the highest risk was observed when both biomarkers were elevated vs not elevated(HR = 8.95,95%CI:3.11-25.73; P < 0.001) and intermediate when only NT-proBNP was elevated vs not elevated(HR = 4.15,95%CI:1.41-12.24; P < 0.01).Moreover,when CA125 was added to the clinical model with NT-proBNP,a 4%(P < 0.05) improvement in the IDI was found.CONCLUSION:CA125 > 60 KU/L identified patients in stable HF with poor survival.Circulating CA125 level adds prognostic value to NT-proBNP level in predicting HF outcomes. | Ana B Méndez Jordi Ordonez-Llanos Andreu Ferrero Mariana Noguero Teresa Mir Josefina Mora Antoni Bayes-Genis Sònia Mirabet Juan Cinca Eulàlia Roig | 2014 | World Journal of Cardiology2014，6，4： | 13 |
| 2 | 基体材料力学性能对316L不锈钢颗粒沉积行为的影响显示文摘研究了基体材料的力学性能对冷喷涂316L不锈钢单颗粒沉积行为的影响.结果表明,除硬度之外,弹性模量和Poisson比也会影响颗粒的沉积行为.这是由于基体性质对颗粒/基体的能量分配和结合机制造成了影响.其中,沉积颗粒的变形行为与颗粒吸收的能量有关,而沉积效率与基体吸收的能量及结合机制有关.根据沉积颗粒的变形行为,将基体分为2类:颗粒几乎不变形,此时基体的硬度和弹性模量皆低于颗粒材料,颗粒与基体的结合主要是机械咬合,推导出可用于推断相同颗粒在基体上沉积趋势的参数E_(para),并以AZ91镁合金为基体进行验证;颗粒发生强烈变形,此时基体的硬度或弹性模量高于颗粒材料,结合机制更为复杂,此时增加颗粒/基体新鲜表面接触面积有利于提高沉积效率. | 马广璐 崔新宇 沈艳芳 Nuria CINCA Josep M.GUILEMANY 熊天英 | 2016 | 金属学报2016，52，12： | 5 |
| 3 | 冷喷涂单颗粒铜在铝基体上的显微结构研究显示文摘采用冷喷涂法在铝(Al)基体上沉积单颗粒铜(Cu),利用聚焦离子束/电子束(FIB/SEM)系统精确定位并原位制备了完整单个颗粒Cu沉积在Al基体上的透射样品,分析其显微结构及形成原因。实验结果表明,撞击过程中温度与应力分布不均匀,导致沉积Cu颗粒不均匀形变。Cu/Al界面受影响较大:颗粒动能转化为形变能和热能,打破了界面处氧化膜,使界面附近温度迅速升高,发生动态再结晶,生成金属间化合物Cu_9Al_4;Cu颗粒内距界面越远的区域,受温度和应力的影响越小,其变形主要是通过晶体内位错增殖和移动;沉积颗粒顶部,远离Cu/Al界面,几乎不受应力和温度影响,保持原始显微结构。 | 马广璐 孔令艳 李铁藩 Nuria Cinca Josep M.Guilemany 熊天英 | 2018 | 稀有金属材料与工程2018，47，4： | 2 |
| 4 | Pharmacokinetics of linagliptin in subjects with hepatic impairment显示文摘 | Ulrike Graefe‐Mody Peter Rose Silke Retlich Arne Ring Lisa Waldhauser Rodica Cinca Hans‐Juergen Woerle | 2012 | British Journal of Clinical Pharmacology2012，，1： | 2 |
| 5 | Mechanical and nanoindentation behavior of TiC–NiTi thermal spray coatings显示文摘 | A. Isalgue J. Fernandez N. Cinca M. Villa J.M. Guilemany | 2012 | Journal of Alloys and Compounds2012，，： | 1 |
| 6 | Structure characterization and wear performance of NiTi thermal sprayed coatings显示文摘 | N Cinca A Isalgué J Fernández J M Guilemany | 2010 | Smart Materials and Structures2010，，8： | 1 |
| 7 | Fac- tors Explaining the Rating of Microfinance Institu tions 显示文摘 | Begona Gutierrez Nieto Cinca Carlos Serrano | 2007 | Nonprofit and Voluntary Sector Quarter- ly2007，6，3： | 1 |
| 8 | High-temperature oxidation of Fe40Al coatings obtained by HVOF thermal spray 显示文摘 | GUILEMANY J M CINCA N DOSTA S LIMA C R C | 2007 | Intermetallics2007，15，： | 1 |
| 9 | Studies of Fe-40Al coatings obtained by high velocity oxy-fuel 显示文摘 | GUILEMANY J M LIMA C R C CINCA N MIGUEL J R | 2006 | Surf Coat Technol2006，201，： | 1 |
| 10 | Pharmacokinetics of linagliptin in subjects with hepatic impairment显示文摘 | Ulrike Graefe‐Mody Peter Rose Silke Retlich Arne Ring Lisa Waldhauser Rodica Cinca Hans‐Juergen Woerle | 2012 | British Journal of Clinical Pharmacology2012，，1： | 1 |
| 11 | Heat diffusion anisotropy in dendritic growth: phase field simulations and experiments in liquid crystals显示文摘 | CINCA R G PISCINA L R CASADEMUNT J | 1998 | Journal of Crystal Growth1998，193，： | 1 |
| 12 | Selecting DEA specifications and ranking units via PCA显示文摘 | Cinca S Molinero C M | 2004 | Journal of the Operational Research Society2004，55，5： | 1 |
| 13 | Circadian variations of electrical properties of the heart显示文摘 | CINCA J MOYA A RIUS J | 1990 | Ann NY Acad Sci1990，601，： | 1 |
| 14 | Time course and rate dependence of Q T interval changes during noncomplicated acute transmural myocardial infarction in human beings显示文摘 | Cinca J Figueras J Tenorio L | 1981 | Am J Cardiol1981，48，： | 1 |
| 15 | Mechanical and corrosion resistance of a new nanostructured Ti-Zr-Ta-Nb alloy显示文摘 | RADUCANU D VASILESCU E COJOCARU V D CINCA I DROB P VASILESCU C DROB S I | 2011 | Journal of the Mechanical Behavior of Biomedical Materials2011，4，7： | 1 |
| 16 | High temperature oxidation of Fe40Al coatings obtained by HVOF thermal spray 显示文摘 | GUILEMANY J M CINCA N DOSTA S | 2007 | Intermetallics2007，15，10： | 1 |
| 17 | Time course and rate dependence of Q-T interval changes during noncomplicated acute transmural myocardial infarction in human beings显示文摘 | Cinca J Figueras J Tenorio L | 1981 | Am J Cardiol1981，48，： | 1 |
| 18 | Glutathione S-transferase activity in human breast tumors 显示文摘 | Colovai A I Stoica A Cinca S A | 1992 | Neoplasma1992，39，4： | 1 |
| 19 | Electrophysiologic effects of unilateral right and left stellate ganglion block on the human heart显示文摘 | Cinca J Evangelista A Mofltoyo J | 1985 | Am Heart J1985，109，1： | 1 |
| 20 | Changes in myocardial electrical impedance induced by coronary artery occlusion in pigs with and without preconditioning:correlation with local ST-segment potential and ventricular arrhythmias显示文摘 | Cinca J Warren M Carreno A | 1997 | Circulation1997，96，9： | 1 |
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