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| 1 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 2 | An example-based mapping method for text categorization and retrieval显示文摘 | Yang Y Chute C G | 1994 | ACM Transactions on Information Systems1994，12，3： | 1 |
| 3 | An Example-based Mapping Method显示文摘 | Yang Y Chute Cq | 1994 | In ACM Transation on Information Systems1994，，7： | 1 |
| 4 | An example-based mapping method for text categorization and retrieval显示文摘 | Yang Y Chute C G | 1994 | ACM Transactions on Informa- tion Systems(TOIS)1994，12，3： | 1 |
| 5 | An example-based mapping method for text categorization and retrieval显示文摘 | YANG Y CHUTE C G | | 0，，03： | 1 |
| 6 | An example- based mapping method for text categorization and retrieval显示文摘 | Yang Y Chute C G | 1994 | ACM Transaction on Information Systems (TOIS)1994，12，3： | 1 |
| 7 | An example-based mapping method for text categorization and retrieval显示文摘 | Yang Y Chute C G | 1994 | ACM Trans on Information Systems1994，12，3： | 1 |
| 8 | An example-based mapping method for text categorization and retrieval显示文摘 | Chute C G | 1994 | ACM Trans on Information Systems1994，12，3： | 1 |
| 9 | An example-based mapping method for text categorization and retrieval 显示文摘 | Yang Y Chute C | 1994 | ACM Transaction on Information Systems (TOIS)1994，12，3： | 1 |
| 10 | An example based mapping method for text categorization and retrieval显示文摘 | Yang Y Chute C | 1994 | ACM Transaction Information Systems1994，12，3： | 1 |
| 11 | An example-based mapping method for text categorization and retrieval显示文摘 | Yang Y Chute C G | 1994 | ACM Trans on Information Systems1994，12，3： | 1 |
| 12 | Pharmacokinetics of levosulpiride after single and multiple intramuscular administrations in healthy Chinese volunteers显示文摘The main purpose of this study was to evaluate the pharmacokinetics of levosulpiride in humans after single and multiple intramuscular injections.Six males and six females received single dose of either 25 mg or 50 mg levosulpiride,or multiple doses of 25 mg every 12 h for 5 consecutive days.In the single 25 mg study,the mean peak plasma concentration(C max)was 441 ng/mL,the mean area under the concentration–time curve from 0 to 36 h(AUC_(0–36))was 1724 ng h/mL,and the mean elimination half-life(t_(1/2))was 7.0 h.In the single 50 mg study,the mean C max was 823 ng/mL,the mean AUC_(0–36) was 3748 ng·h/mL,and the mean t_(1/2) was 6.8 h.After multiple doses of 25 mg levosulpiride,the average plasma concentration(C av)was 136 ng/mL,the fluctuation index(DF)was 3.60,and the accumulation ratio(R)was 1.2.Levosulpiride injections appeared to be well tolerated by the subjects,and can be used for successive administration. | Chuting Gong Janvier Engelbert Agbokponto Wen Yang Ernest Simpemba Xiaohong Zheng Quanying Zhang Li Ding | 2014 | Acta Pharmaceutica Sinica B2014，4，5： | 1 |
| 13 | An example-based mapping method for text categorization and retrieval 显示文摘 | Yang Y Chute C G | 1994 | ACM Transactions on Information Systems1994，12，3： | 1 |
| 14 | An example-based mapping method for text categorization and retrieval显示文摘 | Y Yang C G Chute | 1994 | ACM Trans on Information System1994，12，3： | 1 |
| 15 | An example-based mapping method for text categorization and retrieval显示文摘 | Yang Y Chute C G | 1994 | ACM Transaction on Information Systems1994，12，3： | 1 |
| 16 | An example-based mapping method for text categorization and retrieval显示文摘 | YANG Y CHUTE C | 1994 | ACM Transaction on Information Systems (TOIS)1994，12，3： | 1 |
| 17 | Data-driven resource allocation with trac load prediction显示文摘Wireless big data is attracting extensive attention from operators,vendors and academia,which provides new freedoms in improving the performance from various levels of wireless networks.One possible way to leverage big data analysis is predictive resource allocation,which has been reported to increase spectrum and energy resource utilization eciency with the predicted user behavior including user mobility.However,few works address how the trac load prediction can be exploited to optimize the data-driven radio access.We show how to translate the predicted trac load into the essential information used for resource optimization by taking energy-saving transmission for non-real-time user as an example.By formulating and solving an energy minimizing resource allocation problem with future instantaneous bandwidth information,we not only provide a performance upper bound,but also reveal that only two key parameters are related to the future information.By exploiting the residual bandwidth probability derived from the trac volume prediction,the two parameters can be estimated accurately when the transmission delay allowed by the user is large,and the closed-form solution of global optimal resource allocation can be obtained when the delay approaches in nity.We provide a heuristic resource allocation policy to guarantee a target transmission completion probability when the delay is no-so-large.Simulation results validate our analysis,show remarkable energy-saving gain of the proposed predictive policy over non-predictive policies,and illustrate that the time granularity in predicting trac load should be identical to the delay allowed by the user. | Chuting Yao Chenyang Yang Chih-Lin I | 2017 | Journal of Communications and Information Networks2017，2，1： | 0 |
| 18 | Radioanalytical chemistry for nuclear forensics in China:Progress and future perspective显示文摘A relatively new branch of science-nuclear forensics,aiming at providing the nature,origin,history and possible trafficking route of seized nuclear materials/devices,has been established and rapidly developed over decades to screen illicit nuclear activities.This highly interdisciplinary science is built upon a foundation of analytical chemistry,radiochemistry,nuclear physics,material sciences,geology,and other scientific disciplines,within which radiochemical methodologies and radioanalytical techniques play a key role.The present review provides a brief overview about the crucial aspects of nuclear forensics,including basic content,procedure,concerned elements,common separation,analytical method,and so on.The state of the art and recent progresses of nuclear forensics by research communities in China are reviewed,while selected examples and practical applications are emphasized.The challenges associated with this new area and on-going developments are highlighted and discussed. | Yi Liu Xuepeng Shao Wenting Bu Zhen Qin Youyi Ni Fengcheng Wu Chuting Yang Xiaolin Wang | 2022 | Chinese Chemical Letters2022，33，7： | 0 |
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