|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | BUD2,encoding an S-adenosylmethionine decarboxylase,is required for Arabidopsis growth and development显示文摘Polyamines 在在植物,而是他们的准确角色调整各种各样的发展过程被含有并且他们怎么管理这些过程尚待逃犯。我们这里报导浓密的 Arabidopsis 和矮子异种, bud2,哪个从编码 S-adenosylmethionine decarboxylases (SAMDC ) 的小基因家庭的一个成员的完全的删除的结果为在 polyamine 简历的不可缺少的中介的形成必要合成小径。bud2 植物在开花期,根,和叶柄扩大了脉管的系统,并且 polyamines 的改变的动态平衡。bud2 和 samdc1 的双异种,另一个 SAMDC 成员的击倒的异种,是胚胎致命,证明 SAMDC 为植物胚胎开始是必要的。我们的结果建议 polyamines 为更高的植物的正常生长和发展被要求。 | Chunmin Ge Xia Cui Yonghong Wang Yuxin Hu Zhiming Fu Dongfen Zhang Zhukuan Cheng Jiayang Li | 2006 | Cell Research2006，16，5： | 14 |
| 2 | The BUD2 mutation affects plant architecture through altering cytokinin and auxin responses in Arabidopsis显示文摘植物生长素和细胞激动素的比率在由支持或镇压调整天线建筑学起一个关键作用腋的芽长出。我们以前鉴别了显示的 Arabidopsis 变异的 bud2 改变了根和射击建筑学,它源于 S-adenosylmethionine decarboxylase 的 loss-of-function 4 (SAMDC4 ) 。在这研究,我们证明 BUD2 能被植物生长素导致,并且正式就职依赖于植物生长素发信号。BUD2 的变化导致弱敏到植物生长素和超敏性到细胞激动素,它被胼胝正式就职试金证实。我们的学习建议 polyamines 可以在通过影响细胞激动素和敏感的动态平衡到植物生长素和细胞激动素调整植物建筑学起他们的作用。 | Xia Cui Chunmin Ge Renxiao Wang Huanzhong Wang Weiqi Chen Zhiming Fu Xiangning Jiang Jiayang Li Yonghong Wang | 2010 | Cell Research2010，20，5： | 12 |
| 3 | m^6A Regulates Neurogenesis and Neuronal Development by Modulating Histone Methyltransferase Ezh2显示文摘N6-methyladenosine (m6A),catalyzed by the methyltransferase complex consisting of Mettl3 and Mettl14,is the most abundant RNA modification in mRNAs and participates in diverse biological processes. However,the roles and precise mechanisms of m6A modification in regulating neuronal development and adult neurogenesis remain unclear. Here,we examined the function of Mettl3,the key component of the complex,in neuronal development and adult neurogenesis of mice. We found that the depletion of Mettl3 significantly reduced m6A levels in adult neural stem cells (aNSCs) and inhibited the proliferation of aNSCs. Mettl3 depletion not only inhibited neu-ronal development and skewed the differentiation of aNSCs more toward glial lineage,but also affected the morphological maturation of newborn neurons in the adult brain. m6A immunoprecip-itation combined with deep sequencing (MeRIP-seq) revealed that m6A was predominantly enriched in transcripts related to neurogenesis and neuronal development. Mechanistically,m6A was present on the transcripts of histone methyltransferase Ezh2,and its reduction upon Mettl3 knockdown decreased both Ezh2 protein expression and consequent H3K27me3 levels. The defects of neurogenesis and neuronal development induced by Mettl3 depletion could be rescued by Ezh2 overexpression. Collectively,our results uncover a crosstalk between RNA and histone modifica-tions and indicate that Mettl3-mediated m6A modification plays an important role in regulating neurogenesis and neuronal development through modulating Ezh2. | Junchen Chen Yi-Chang Zhang Chunmin Huang Hui Shen Baofa Sun Xuejun Cheng Yu-Jie Zhang Yun-Gui Yang Qiang Shu Ying Yang Xuekun Li | 2019 | Genomics, Proteomics & Bioinformatics2019，17，2： | 12 |
| 4 | A Transgenic Study on Affecting Potato Tuber Yield by Expressing the Rice Sucrose Transporter Genes OsSUT5Z and OsSUT2M显示文摘在许多植物,蔗糖 transporters 为从来源和进口的两个蔗糖出口是必要的进水池,显示功能在吸收划分。为了调查蔗糖 transporters 是否能改进淀粉的收益,种,土豆植物(茄属 tuberosum L。cv。 | Aijun Sun Yan Dai Xinsheng Zhang Chunmin Li Kun Meng Honglin Xu Xiaoli Wei Guifang Xiao Pieter B.F, Ouwerkerk Mei Wang Zhen Zhu | 2011 | Journal of Integrative Plant Biology2011，53，7： | 9 |
| 5 | IL-37b suppresses T cell priming by modulating dendritic cell maturation and cytokine production via dampening ERK/NF-κB/S6K signalings显示文摘Interleukin 37b (IL-37b ) 在压制有免疫力的回答起一个关键作用,部分由 modulating 树枝状的房间(DC ) 的功能。然而,精确机制大部分仍然是未知的。这里,我们在回答由 DC 导致了的 DC 成熟和 T 房间上调查了 IL-37b 的效果,并且探索了深奥发信号的小径。它被发现那 IL-37b 下面调整在 vitro 的 DC 上的 co-stimulatory 分子 CD80 和 CD86 的表情。同时,支持 inflammatory cytokines 的表情例如 TNF-6, 和 IL-6,被压制,当时 T 房间的表示禁止的 cytokine TGF- 在 IL-37b-treated DC 被增加。另外, T 房间上的 DC 的激活效果被 IL-37b 损害。我们进一步表明细胞外的调整单人赛的 kinase (英皇家空军之阶级最低之兵) ,原子 factor-B (NF-B ) ,和表明小径的 mTOR-S6K 涉及 IL-37b 导致的 DC 的抑制。这被化学禁止者的同样镇压的效果在 DC 在 IL-6 和 TNF- 的表情上对 NF-B,英皇家空军之阶级最低之兵,和 S6K 证实。在结论,这些结果证明 IL-37b 由在英皇家空军之阶级最低之兵, NF-B,和基于 S6K 的禁止的发信号小径包含在 T 房间 priming 压制了 DC 成熟和 immunostimulatory 能力。 | Wantong Wu Weiqiang Wang Yun Wang Wenwen Li Gang Yu Zhonglong Li Chunmin Fang Yue Shen Zhina Sun Ling Han Juan Yu Lijun Fang Song Chen Kui Dong Zhongchao Han Hanzhi Liu Yuechen Luo Xiaoming Feng | 2015 | Acta Biochimica et Biophysica Sinica2015，47，8： | 8 |
| 6 | Experimental investigation of thermal effect on cavitation characteristics in a liquid rocket engine turbopump inducer显示文摘The objective of this paper is to investigate the effect of water temperature on cavitation characteristics in a turbopump inducer,a series of experiments at different temperatures have been conducted in a newly developed visualization test facility.It is found that higher temperature shows little influence on the non-cavitation performance and breakdown characteristic in the investigated range.The relationship between cavitation development and pressure fluctuation has been discussed in detail.Higher temperature displays a remarkable stabilization effect on the cavitation excited pressure.In particular,the inception cavitation numbers of both the super-synchronous rotating cavitation and synchronous rotating cavitation are decreased at higher temperatures,and the corresponding frequencies are not affected,while the amplitudes are distinctly reduced,and the occurrence range of synchronous rotating cavitation is significantly narrowed.A generalized RayleighPlesset equation has been employed to account for the thermal effect on the bubble development,which may provide a deep insight in understanding the experimental results.Thermal effect is found to act as a remarkable dissipation mechanism to suppress the bubble growth,smooth the collapse.In particular,the excited pressure during collapse is smaller at higher temperatures,which may lead to the stabilization effect of high temperature in this study. | Chunmin WANG Le XIANG Yonghua TAN Hui CHEN Kaifu XU | 2021 | Chinese Journal of Aeronautics2021，34，8： | 7 |
| 7 | Progressive paradoxical sleep deprivation impairs partial memory following learning tasks in rats显示文摘BACKGROUND: Complex learning tasks result in a greater number of paradoxical sleep phases, which can improve memory. The effect of paradoxical sleep deprivation, induced by 'flower pot' technique, on spatial reference memory and working memory require further research. OBJECTIVE: To observe the effect of progressive paradoxical sleep deprivation in rats, subsequent to learning, on memory using the Morris Water Maze. DESIGN, TIME AND SETTING: Controlled observation experiment. The experiment was performed at the Laboratory of Neurobiology, Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Lanzhou University from December 2006 to October 2007. MATERIALS: Twenty-eight, male, Wistar rats, 3-4 months old, were provided by the Experimental Animal Center of Lanzhou University. The Morris Water Maze and behavioral analyses system was purchased from Genheart Company, Beijing, China. METHODS: All animals, according to a random digits table, were randomly divided into paradoxical sleep deprivation, tank control, and home cage control groups. Paradoxical sleep deprivation was induced by the 'flower pot' technique for 72 hours, housing the rats on small platforms over water. Rats in the 'tank control' and 'home cage control' groups were housed either in a tank with large platforms over the water or in normal cages without paradoxical sleep deprivation. MAIN OUTCOME MEASURES: Morris Water Maze was employed for task learning and spatial memory testing. Rats in all groups were placed at six random starting points each day for four consecutive days. Each placement was repeated for two trials; the first trial represented reference memory and the second working memory. Rats in the first trial were allowed to locate the submerged platform within 120 seconds. Data, including swimming distance, escape latency, swimming velocity, percentage of time in correct quarter, and memory scores were recorded and analyzed automatically by behavioral analyses systems for Morris Water Maze. RESULTS: Twenty-eight rats were included in the final analysis, without any loss. In the first trial, between day 2 and 4, escape latency and swimming distance increased significantly in the paradoxical sleep deprivation group compared to the home cage control and tank control groups (P < 0.01); percentage of time in correct quarter and memory scores, however, decreased in the paradoxical sleep deprivation group compared to the home cage control and tank control groups (P < 0.01). The escape latency, swimming distance, percentage of time in correct quarter, and memory scores in the second trial was not significantly different among the three groups (P > 0.05). CONCLUSION: Paradoxical sleep deprivation inhibits spatial reference memory, but not working memory. | Chunmin Zhu Xiangrong Yao Weisheng Zhang Yanfeng Song Yiping Hou | 2008 | Neural Regeneration Research2008，3，6： | 4 |
| 8 | Interference image spectroscopy for upper atmospheric wind field measurement显示文摘 | Zhang Chunmin Zhao Baochang Bin Xiangli | | 0，，06： | 1 |
| 9 | Effect of boronizing temperature and time on microstructure and abrasion wear resistance of Cr12Mn2V2 high chromium cast iron显示文摘 | Chunmin Li Baoluo Shen Guijiang Li Chao Yang | 2008 | Surface & Coatings Technology2008，，24： | 1 |
| 10 | Toward the optimal itinerary-based kNN query processing in mobile sensor networks显示文摘 | Wu Shanhuang Chuang Kunta Chen Chunmin | 2008 | IEEE Transactions on Knowledge and Data Engineering2008，20，12： | 1 |
| 11 | Feedstock Characteristic Index and Critical Properties of Heavy Crudes and Petroleum Residue显示文摘 | Zhao Suoqi Xu Zhiming Xu Chunmin | 2004 | Journal of Petroleum Science and Engineering2004，41，13： | 1 |
| 12 | Design and optimization of planar structure micro-hotplate 显示文摘 | Zhang Zili Yin Chenbo Tao Chunmin | 2011 | Procedia Engineering2011，12，： | 1 |
| 13 | Segmenting customers by transaction data with concept hierarchy显示文摘 | Hsu Fangming Lu Lipang Lin Chunmin | 2012 | Expert Systems with Applications2012，39，6： | 1 |
| 14 | The accurate calculation of the Fourier transform of the pure Voigt function 显示文摘 | Jian He Chunmin Zhang | 2005 | J Opt A: Pure and Appl Opt2005，7，： | 1 |
| 15 | A static and divided mirror michelson interferometer for measuring atmospheric winds显示文摘 | Bu Zhichao Zhang Chunmin Zhao Baochang | | 0，，： | 1 |
| 16 | Synthesis and Characterization of MCM-41-Type Composite Materials Prepared from ZSM-5 Zeolite显示文摘 | Song Chunmin Jiang Jie Yan Zifeng | 2008 | J Porous Mater2008，15，2： | 1 |
| 17 | A static polarization imaging spectrometer based on a Savart polariscope显示文摘 | Chunmin Zhang Bin Xiangli Baochang Zhao Xingjing Yuan | 2002 | Optics Communications2002，，1： | 1 |
| 18 | Pilot synthesis and commercial application in FCC catalyst of MCM - 41 zeolite 显示文摘 | Da Jianwen Song Chunmin Qian ling | 2008 | Journal of Porous Materials2008，15，2： | 1 |
| 19 | Porting of EtherCAT soil master and developing of a new type of open motion controller显示文摘 | Ma ChunMin Yang JianWu Fei RenYuarl | 2010 | Applied Mechanics and Materials2010，3435，： | 1 |
| 20 | Interference image spectroscopy for upper atmospheric wind field measurement显示文摘 | Chunmin Zhang Baochang Zhao Bin Xiangli | 2006 | Optik2006，117，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员