|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Zircon U-Pb and geochemical analyses for leucocratic intrusive rocks in pillow lavas in the Danfeng Group,north Qinling Mountains,China显示文摘Field observation showed that there are many irregular leucocratic intrusive rocks in pillow lavas in the Danfeng Group in the Xiaowangjian area, north Qinling orogenic belt. Photomicrographs indicated that the protoliths of those altered leucocratic intrusive rocks are dioritic rocks. Geochemical analyses showed that pillow lavas have a range of SiO2 from 47.35% to 51.20%, low abundance of TiO2 from 0.97% to 1.72%, and percentages of MgO (MgO#=41―49). Chondrite-normalized REE patterns of pillow lavas are even, indicative of a weak differentiation between LREE and HREE (La/YbN=1.52―0.99). N-MORB-normalized trace element abundances showed that pillow lavas are enriched in incompatible elements (e.g., K, Rb, and Ba). Leucocratic intrusive rocks in pillow lavas have a wide range of SiO2 from 53.85%―67.20%, low abundances of TiO2 from 0.51%―1.10%, and MgO (MgO#=40―51), and higher percentages of Al2O3 (13.32%―16.62%) and concentration of Sr (342-539 μg/g), ratios of Na2O/K2O (2―7) and Sr/Y (17―28). Chondrite-normalized REE patterns of leucocratic intrusive rocks showed highly differentiation between LREE and HREE (La/YbN=12.26―19.41). N-MORB-normalized trace element abundances showed that leucocratic intrusive rocks are enriched in incompatible elements (e.g., K, Rb, and Ba), and significantly depleted in HFSE (e.g., Nb, Ta, Zr and Ti), indicative of a relationship to subduction. Isotopically, leucocratic intrusive rocks have a similar εNd(t) (+7.45―+13.14) to that of MORB (+8.8―+9.7), which indicates that those leucocratic intrusive rocks sourced from depleted mantle most likely. SHRIMP U-Pb analyses for zircon showed that those leucocratic intrusive rocks were formed at 442±7 Ma, yielding an age of subduction in the early Paleozoic in the north Qinling orogenic belt. | Yan QuanRen Chen JunLu Wang ZongQi Yan Zhen Wang Tao Li QiuGen Zhang ZongQing Jiang ChunFa | 2008 | Science China Earth Sciences2008，51，2： | 14 |
| 2 | Construction of brewing-wine Aspergillus oryzaepyrG- mutant bypyrG gene deletion and its application in homology transformation显示文摘 | Yu Du Guizhen Xie Chunfa Yang Baishan Fang Hongwen Chen | 2014 | Acta Biochimica et Biophysica Sinica2014，46，6： | 6 |
| 3 | Decrease in the Ki67 index during neoadjuvant chemotherapy predicts favorable relapse-free survival in patients with locally advanced breast cancer显示文摘Objective: The purpose of this study was to explore the optimal cutoffs of the three parameters of Ki67 during NAC for predicting patient prognosis and investigate whether the optimal cutoffs of the Ki67 values were associated with relapse-free survival(RFS) or breast cancer-specific survival(BCSS).Methods: A total of 92 patients with locally advanced breast cancer(LABC), who had residual disease after NAC were retrospectively investigated.The optimal cutoff values of the Ki67 parameters were assessed by the online algorithm Cutoff Finder.Kaplan-Meier analysis, the log-rank test and Cox regression analysis were carried out to analyze survival.Results: The optimal cutoff values for the postsurgical Ki67 level and the decrease in the Ki67 level during NAC were defined as 25% and 12.5%, respectively.According to the univariate survival analysis, a higher Ki67 level in residual disease was associated with poor RFS(P = 0.004) and BCSS(P = 0.014).In addition, a Ki67 expression decrease > 12.5% during NAC was related to favorable RFS(P = 0.007), but was not related to BCSS(P = 0.452).Cox regression analysis showed that the Ki67 expression decrease(> 12.5% vs.≤ 12.5%) and histological grade(grade 3 vs.grade 1-2) were the independent factors associated with RFS(P =0.020 and P = 0.023, respectively), with HR values of 0.353(95% CI: 0.147-0.850) and 3.422(95% CI: 1.188-9.858), respectively.Conclusions: The Ki67 decrease was one of the independent factors associated with RFS in LABC patients with residual disease after receiving NAC. | Chunfa Chen Yuling Zhang Ziyi Huang Jundong Wu Wenhe Huang Guojun Zhang | 2019 | Cancer Biology & Medicine2019，16，3： | 4 |
| 4 | NMR used to study the side-reactions between peroxides and antioxidants during the reactive extrusion process of the impact polypropylene显示文摘Side reaction pathways are observed to occur between antioxidants and peroxide during the processing of multiple resin grades mediated by controlled peroxide-induced degradation of impact polypropylene.In the present work,the reaction mechanism and main by-products between antioxidants and peroxides were investigated.The results demonstrate that peroxides greatly accelerate the decomposition reactions,and the free radicals formed from peroxide decomposition react with,for example,the antioxidant AO1010 to produce dehydrogenation of phenyl propionic unit(s)at the a position(cinnamic acid ester moiety),which generates a conjugated system leading to the increased color of the product.It is the first time to confirm the cinnamic acid moiety's existence and report its NMR data.Further,this work confirms the dehydrogenation mechanism by comparison with different sterically hindered phenolic antioxidants.It also systematically summarizes the oxidation and degradation mechanism of AO168 and AO1010 under air and peroxide environments,respectively.Based on present study,clear guidelines are obtained to improve the quality of polymeric products,especially the appearance and stability,during product development. | Chunfa Li Ting Huang Yubin Bao Zhe Chen Guangxin Lin | 2022 | Magnetic Resonance Letters2022，2，2： | 1 |
| 5 | Analysis of chemical composition of polysaccharides from Poria cocos Wolf and its anti-tumor activity by NMR spectroscopy显示文摘 | Ke Ruidian Lin Chunfa Chen Yi | 2010 | carbohydrate Polymers2010，80，： | 1 |
| 6 | Identification of ions present in LiF-DyF_3 melts and the mechanism of Dy_2O_3 dissolution therein显示文摘Herein, the present paper were attempted to identify ions in LiF-DyF_3 melts according to the law of decreasing primary crystallization temperature and model analysis. Specifically.the primary crystallization temperatures of LiF-DyF_3 and LiF-DyF_3-Dy_2O_3 melts with various DyF_3 and Dy_2O_3 contents were determined by differential scanning calorimetry(DSC), and reactions occurring in the above melts were investigated using ideal dilute solution(Temkin and Flood) models. Moreover, crystal phases produced by rapid solidification of LiF-DyF_3, LiF-Dy_2O_3, DyF_3-Dy_2O_3, and LiF-DyF_3-Dy_2O_3 melts were identified by X-ray diffraction(XRD) analysis. The primary crystallization temperature of LiF-DyF_3 melts exhibits an approximately linear decrease with increasing molar fraction of DyF_3, and the general formula of complex ions in these melts is expressed as DyF_x^((3-x)),e.g., DyF_4^-. Finally, we investigated the dissolution of Dy_2O_3 in LiF-DyF_3 melts, showing that it was chemical in nature and afforded Dy_(1+x)O_(3x)F_(3-3x) and DyOF. | Chunfa Liao Shumei Chen Xu Wang Boqing Cai Jueyuan Lin Yunfen Jiao Yanliang Zeng | 2019 | Journal of Rare Earths2019，37，2： | 1 |
| 7 | Excitation-wavelength-dependent fluorescent organohydrogel for dynamic information anti-counterfeiting显示文摘Anti-counterfeiting labels with various fluorescent colors are of great importance in information encryption-decryption,but are still limited to static information display.Therefore,it is urgent to develop new materials and encryption-decryption logic for improving the security level of secret information.In this study,an organohydrogel made up of poly(N,N-dimethylacrylamide)(pDMA)hydrogel network and polyoctadecyl methacrylate(pSMA)organogel network that copolymerized with two fluorophores,6-acrylamidopicolinic acid moieties(6APA,fluorescent ligand)and spiropyran units(SPMA,photochromic monomer),was prepared by a two-step interpenetrating method.As UV light of 365nm and 254nm can both cleave C_(spiro)-O bonds of SPMA,and the green fluorescence of 6APA-Tb^(3+) can only be excited by 254nm light,the organohydrogel displays yellow and red under the irradiation of 254nm and 365 nm,respectively.In addition to wavelength selectivity,these two fluorophores are thermal-responsive,leading to the fluorescence variation of the organohydrogel during heating process.As a result,secret information loaded on the organohydrogel can be decrypted by the irradiation of UV light,and the authenticity of the information can be further identified by thermal stimulation.Our fluorescent organohydrogel can act as an effective anti-counterfeiting label to improve the information security and protect the information from being cracked. | Dong Guo Xiaoxia Le Hui Shang Fuqing Shan Danyang Li Chunfa Ouyang Tao Chen | 2023 | Chinese Chemical Letters2023，34，11： | 0 |
| 8 | Palladium-Catalyzed Cross-Coupling of Fluorinated Vinyl Chlorides with Terminal Alkynes: A General Protocol to Fluorinated Enynes显示文摘为氟化的结合的 enynes 的准备的一个有效、划算的方法被描述。方法与象氯化物,胺, cyano 和酉旨组那样的许多功能的组兼容。方法能也被扩大到联合(R, Z ) 有中等收益的 -3-(2-chloro-1,2-difluorovinyl)-4-alkyloxazolidin-2-one (3 ) 。 | Sheng Chen Chunfa Xu Long Lu Qilong Shen | 2013 | Chinese Journal of Chemistry2013，31，7： | 0 |
| 9 | Skeletal contraction:A novel strategy to access multisubstituted cyclobutane显示文摘The polysubstituted and spirocyclic cyclobutanes were efficiently constructed by the utilization of a novel skeletal contraction strategy which only took one-step synthesis from the readily accessible pyrrolidines.The mechanistic studies indicated that a key intermediate N-aminated pyrrolidine was formed initially and subsequent extrusion of a nitrogen via a radical pathway completed the transformation.This practical methodology was further highlighted by the concise,formal synthesis of the cytotoxic natural product piperarborenine B. | Chunfa Xu V.U.Bhaskara Rao Fen-Er Chen | 2022 | Green Synthesis and Catalysis2022，3，1： | 0 |
| 10 | Nucleophilic Trifluoromethylthiolation of Alkyl Chlorides, Bromides and Tosylates显示文摘有 AgSCF 3 的烷基氯化物,溴化物和 tosylates 的直接亲核的 trifluoromethylthiolation 被描述。这被发现 nBu 4 NI 或 nBu 4 NI/nBu 4 NBr 显著地提高了反应率。反应条件是温和的,因此允许许多功能的组的忍耐。 | Chunfa Xu Qingyun Chen Qilong Shen | 2016 | Chinese Journal of Chemistry2016，34，5： | 0 |
| 11 | Functionalizing DNA nanostructures with natural cationic amino acids显示文摘Complexing self-assembled DNA nanostructures with various functional guest species is the key to unlocking new and exciting biomedical applications.Cationic guest species not only induce magnesium-free DNA to self-assemble into defined structures but also endow the final complex nanomaterials with new properties.Herein,we propose a novel strategy that employs naturally occurring cationic amino acids to induce DNA self-assembly into defined nanostructures.Natural L-arginine and L-lysine can readily induce the assembly of tile-based DNA nanotubes and DNA origami sheets in a magnesium-free manner.The self-assembly processes are demonstrated to be pH-and concentration-dependent and are achieved at constant temperatures.Moreover,the assembled DNA/amino acid complex nanomaterials are stable at a physiological temperature of 37◦C.Substituting L-arginine with its D form enhances its serum stability.Further preliminary examination of this complex nanomaterial platform for biomedical applications indicates that DNA/amino acids exhibit distinct cellular uptake behaviors compared with their magnesium-assembled counterparts.The nanomaterial mainly clusters around the cell membrane and might be utilized to manipulate molecular events on the membrane.Our study suggests that the properties of DNA nanostructures can be tuned by complexing them with customized guest molecules for a designed application.The strategy proposed herein might be promising to advance the biomedical applications of DNA nanostructures. | Dong Wang Chunfa Chen Qian Liu Qianwen Zhao Di Wu Yue Yuan Chaowang Huang Xiaorong Sun Chunji Huang David Tai Leong Guansong Wang Hang Qian | 2021 | Bioactive Materials2021，6，9： | 0 |
| 12 | A case of primary neuroendocrine breast carcinoma that responded to neo-adjuvant chemotherapy显示文摘主要 neuroendocrine 胸癌(NEBC ) 是乳癌的一种很稀罕的类型。二典型 biomarkers,也就是 CgA 和 Syn,应该 immunohistochemically 被检测诊断 NEBC。在这研究,有 8.3 厘米椠瑮獥楴慮? 的一个大团的一个 43 岁的女人 ? 呓 ? 桴 ? 潮敶 ? 獵? 景琠牡敧整 ? 桴牥灡 ? 湡 ? 条牧獥楳敶猠牵楧慣? 牴慥浴湥 ? 牰摯 ' 讚瓲剳 V 潳慮汢? 潧摯猠牵楶慶? 畯 ' 咒矗? | Xiaolong Wei Chunfa Chen Didi Xi Jinwen Bai Wenhe Huang Luoxiang Rong Mingyao Wu Guojun Zhang | 2015 | Frontiers of Medicine2015，9，1： | 0 |
| 13 | Synergistic Pd/Cu catalysis enabled cross-coupling of glycosyl stannanes with sulfonium salts to access C-aryl/alkenyl glycals显示文摘A highly efficient coupling of glycosyl stannanes and sulfonium salts enabled by synergistic Pd/Cu catalysis is disclosed, facilitating the construction of C-aryl/alkenyl glycals under mild conditions in high yields.The protocol tolerates a wide scope of functional groups including ketone, cyano, ester, amide, nitro,halide. The one-pot formal C–H glycosylation starting from arene is demonstrated with a reaction sequence of dibenzothiophenylation/Stille coupling. Besides, a gram-scale reaction is performed successfully,showing the high applicability of this protocol. | Weitao Yan Mingwen Zheng Peihsuan Chuang Hao Sun Shiping Wang Chunfa Xu Fen-Er Chen | 2023 | Chinese Chemical Letters2023，34，7： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员