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| 1 | 亚太地区慢性乙型肝炎治疗共识(2012最新版)显示文摘自2008年至今,有大量关于慢性HBV感染的自然史和治疗的最新数据不断涌现。其中包括慢性HBV感染的无症状感染者,以社区为基础的队列研究,HBV基因型的作用,非药物诱导的自然HBV变异型毒株,无创性肝纤维化评估方法的应用,HBsAg定量在临床中的应用,更有效的新治疗药物和新治疗方案等等。来自亚太地区的专家审查和评估了相关数据,并共同商讨了近年来报道的最有意义的发现,基于此,对2008年版的亚太地区慢性乙型肝炎治疗共识进行修订,同时对2008年版治疗指南定义的关键词组进行了修订。修订后的指南包括以下几方面内容:一般治疗,肝纤维化评价适应证,何时开始治疗或停药,初始抗病毒治疗药物的选择,如何监测治疗中和治疗后的患者。关于特殊人群的治疗建议中包括了对妊娠妇女,已发生耐药,合并其他病毒感染,肝功能失代偿,接受免疫抑制治疗、化疗,肝移植或肝细胞癌患者的具体治疗建议。 | 廖运范 Jia-HorngKao Teerha Piratvisuth Henry Lik Yuen Chan Rong-Nan Chien Chun-Jen Liu Ed Gane Stephen Locarnini Seng-Gee Lim Kwang-Hyub Han Deepak Amarapurkar Graham Cooksley Wasim Jafri Rosmawati Mohamed Wan-Long Chuang Laurentius A.Lesmana Jose D.Sollano Dong-Jin Suh Masao Omata 刘颖 徐莹 李芸 黄祖雄 樊蓉 李小溪 吕国涛 周彬 孙剑 侯金林 | 2012 | 临床肝胆病杂志2012，28，8： | 182 |
| 2 | Precise orbit determination of Beidou Satellites with precise positioning显示文摘Chinese Beidou satellite navigation system constellation currently consists of eight Beidou satellites and can provide preliminary service of navigation and positioning in the Asia-Pacific Region.Based on the self-developed software Position And Navigation Data Analysis(PANDA) and Beidou Experimental Tracking Stations (BETS),which are built by Wuhan University,the study of Beidou precise orbit determination,static precise point positioning (PPP),and high precision relative positioning,and differential positioning are carried out comprehensively.Results show that the radial precision of the Beidou satellite orbit determination is better than 10 centimeters.The RMS of static PPP can reach several centimeters to even millimeters for baseline relative positioning.The precision of kinematic pseudo-range differential positioning and RTK mode positioning are 2-4 m and 5-10 cm respectively,which are close to the level of GPS precise positioning.Research in this paper verifies that,with support of ground reference station network,Beidou satellite navigation system can provide precise positioning from several decimeters to meters in the wide area and several centimeters in the regional area.These promising results would be helpful for the implementation and applications of Beidou satellite navigation system. | SHI Chuang ZHAO QiLe LI Min TANG WeiMing HU ZhiGang LOU YiDong ZHANG HongPing NIU XiaoJi LIU JingNan | 2012 | Science China Earth Sciences2012，55，7： | 61 |
| 3 | 纳络酮对败血症通气抑制的预防作用显示文摘 | 高成新 Chuang | 1991 | 中华结核和呼吸杂志1991，14，6： | 41 |
| 4 | Bile duct injuries associated with laparoscopic and open cholecystectomy: Sixteen-year experience显示文摘AIM: To summarize the experience in diagnosis, management and prevention of iatrogenic bile duct injury (IBDI). METHODS: A total of 210 patients with bile duct injury occurred during cholecystectomy admitted to Hunan Provincial People’s Hospital from March 1990 to March 2006 were included in this study for retrospective analysis. RESULTS: There were 59.5% (103/173) of patients with IBDI resulting from the wrong identification of the anatomy of the Calot’s triangle during cholecystectomy. The diagnosis of IBDI was made on the basis of clinical features, diagnostic abdominocentesis and imaging findings. Abdominal B ultrasonography (BUS) was the most popular way for IBDI with a diagnostic rate of 84.6% (126/149). Magnetic resonance cholangiography (MRC) could reveal the site of injury, the length of injured bile duct and variation of bile duct tree with a diagnostic rate 100% (45/45). According to the site of injury, IBDI could be divided into six types. The most common type (type 3) occurred in 76.7% (161/210) of the patients and was treated with partial resection of the common hepatic duct and common bile duct. One hundred and seventy-six patients were followed up. The mean follow-up time was 3.7 (range 0.25-10) years. Good results were achieved in 87.5% (154/176) of the patients. CONCLUSION: The key to prevention of IBDI is to follow the 'identifying-cutting-identifying' principle during cholecystectomy. Re-operation time and surgical procedure are decided according to the type of IBDI. | Jin-Shu Wu Chuang Peng Xian-Hai Mao Pin Lv | 2007 | World Journal of Gastroenterology2007，13，16： | 32 |
| 5 | A review of topology optimization for additive manufacturing:Status and challenges显示文摘Topology optimization was developed as an advanced structural design methodology to generate innovative lightweight and high-performance configurations that are difficult to obtain with conventional ideas.Additive manufacturing is an advanced manufacturing technique building asdesigned structures via layer-by-layer joining material,providing an alternative pattern for complex components.The integration of topology optimization and additive manufacturing can make the most of their advantages and potentials,and has wide application prospects in modern manufacturing.This article reviews the main content and applications of the research on the integration of topology optimization and additive manufacturing in recent years,including multi-scale or hierarchical structural optimization design and topology optimization considering additive manufacturing constraints.Meanwhile,some challenges of structural design approaches for additive manufacturing are discussed,such as the performance characterization and scale effects of additively manufactured lattice structures,the anisotropy and fatigue performance of additively manufactured material,and additively manufactured functionally graded material issues,etc.It is shown that in the research of topology optimization for additive manufacturing,the integration of material,structure,process and performance is important to pursue high-performance,multi-functional and lightweight production.This article provides a reference for further related research and aerospace applications. | Jihong ZHU Han ZHOU Chuang WANG Lu ZHOU Shangqin YUAN Weihong ZHANG | 2021 | Chinese Journal of Aeronautics2021，34，1： | 33 |
| 6 | Average slip-rate and recent large earthquake ruptures along the Garzê-Yushu fault显示文摘Our field investigation obtains new evidence of the later Quaternary activity and recent large earthquake ruptures of the Garzê-Yushu fault. The average left-lateral slip-rate along the fault is determined to be (12 ± 2) mm/a for the last 50000 years from both offset landforms and ages of the correlative sediments. This result is very close to the estimated average left-lateral slip-rate for the Xianshuihe fault, suggesting that the horizontal movement along the northern boundary of the Sichuan-Yunnan active tectonic block and the northeastern boundary of the Qiangtang active tectonic block has been basically harmonious during the later Quaternary period. Remains of ground ruptures of recent large earthquakes have been discovered along all 3 segments of the fault, of which, the 1896 rupture on the northwestern segment is at least 70 km long, and its corresponding earthquake could be of moment magnitude 7.3. The latest rupture on the middle segment of the fault has a length of about 180 km, and was produced by an unknown-age large earthquake that could have a moment magnitude of about 7.7. Along the southeastern segment of the fault, the latest unknown-age rupture is about 65 km long and has a maximum left-lateral coseismic displacement of 5.3 m, and its corresponding earthquake is estimated to be as large as about 7.3 of moment magnitude. Based on relevant investigation, an inference has been drawn that the later two large earthquakes probably occurred in 1854 and 1866, respectively. These demonstrate that the individual segments of the studied Garzê-Yushu fault are all able to produce large earthquakes. | WEN Xueze (闻学泽) XU Xiwei (徐锡伟) ZHENG Rongzhang (郑荣章) XIE Yingqing (谢英情) WAN Chuang (万 创) | 2003 | Science China Earth Sciences2003，46，z2： | 24 |
| 7 | PBPK modeling and simulation in drug research and development显示文摘Physiologically based pharmacokinetic(PBPK) modeling and simulation can be used to predict the pharmacokinetic behavior of drugs in humans using preclinical data.It can also explore the effects of various physiologic parameters such as age,ethnicity,or disease status on human pharmacokinetics,as well as guide dose and dose regiment selection and aid drug–drug interaction risk assessment.PBPK modeling has developed rapidly in the last decade within both the field of academia and the pharmaceutical industry,and has become an integral tool in drug discovery and development.In this mini-review,the concept and methodology of PBPK modeling are briefly introduced.Several case studies were discussed on how PBPK modeling and simulation can be utilized through various stages of drug discovery and development.These case studies are from our own work and the literature for better understanding of the absorption,distribution,metabolism and excretion(ADME) of a drug candidate,and the applications to increase efficiency,reduce the need for animal studies,and perhaps to replace clinical trials.The regulatory acceptance and industrial practices around PBPK modeling and simulation is also discussed. | Xiaomei Zhuang Chuang Lu | 2016 | Acta Pharmaceutica Sinica B2016，6，5： | 21 |
| 8 | Effects of Cu,Fe and Co addition on the glass-forming ability and mechanical properties of Zr-Al-Ni bulk metallic glasses显示文摘The thermal stability,glass-forming ability(GFA) and mechanical properties of Zr60Al15Ni25xTMx(TM = Cu,Fe and Co,x = 0-10) bulk metallic glasses(BMGs) were systematically investigated.Additional 5-10 at.% Cu greatly enhances the thermal stability and GFA of the base alloy.Zr60Al15Ni15Cu10 BMG exhibits the largest supercooled liquid region of 104 K and critical diameter of 18 mm.However,addition of 5-10 at.% Fe or Co decrease the thermal stability and GFA.In addition,the plasticity of the BMG can be improved by adding of Cu,while the strength is decreased slightly.Zr60Al15Ni20Cu5 BMG has the largest plastic strain of 5.5% with a yield stress of 1755 MPa and Young's modulus of 83 GPa.Addition of Co brings an increase of strength but a lower of plasticity,and additional Fe reduces the strength and plasticity simultaneously. | LI YanHui ZHANG Wei DONG Chuang AKIHIRO Makino | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，12： | 19 |
| 9 | Overexpression of OsPAP10a, A Root-Associated Acid Phosphatase, Increased Extracellular Organic Phosphorus Utilization in Rice显示文摘Phosphorus (P) deficiency is a major limitation for plant growth and development. Among the wide set of responses to cope with low soil P, plants increase their level of intracellular and secreted acid phosphatases (APases), which helps to catalyze inorganic phosphate (Pi) hydrolysis from organophosphates. In this study we characterized the rice (Oryza sativa) purple acid phosphatase 10a (OsPAP10a). OsPAP10a belongs to group Ia of purple acid phosphatases (PAPs), and clusters with the principal secreted PAPs in a variety of plant species including Arabidopsis. The transcript abundance of OsPAP10a is specifically induced by Pi deficiency and is controlled by OsPHR2, the central transcription factor controlling Pi homeostasis. In gel activity assays of root and shoot protein extracts, it was revealed that OsPAP10a is a major acid phosphatase isoform induced by Pi starvation. Constitutive overexpression of OsPAP10a results in a significant increase of phosphatase activity in both shoot and root protein extracts. In vivo root 5-bromo-4-chloro-3-indolyl-phosphate (BCIP) assays and activity measurements on external media showed that OsPAP10a is a root-associated APase. Furthermore, overexpression of OsPAP10a significantly improved ATP hydrolysis and utilization compared with wild type plants. These results indicate that OsPAP10a can potentially be used for crop breeding to improve the efficiency of P use. | Jingluan Tian Chuang Wang Qian Zhang Xiaowei He James Whelan Huixia Shou | 2012 | Journal of Integrative Plant Biology2012，54，9： | 18 |
| 10 | Upper ocean near-inertial response to 1998 Typhoon Faith in the South China Sea显示文摘During the South China Sea monsoon experiment (SCSMEX),three autonomous temperature line acquisition system (ATLAS) buoys with acoustic Doppler current profiler (ADCP) were moored in the South China Sea to measure temperature,salinity and current velocity.Typhoon Faith passed through about 250 km south to one of the mooring buoys located at 12 58.5 N,114 24.5 E from December 11 to 14,1998.The data analysis indicates that the typhoon winds induce a great increase in the kinetic energy at near-inertial frequencies with two maxima in the mixed layer and thermocline.The near-inertial oscillations were observed at the upper 270 m in the wake of Typhoon Faith.The oscillations were originally excited in the sea surface layer and propagated downward.The amplitudes of the oscillations decrease with depth except in the thermocline.The near-inertial oscillation signals are also remarkable in temperature and salinity fields. | SUN Lu ZHENG Quan'an TANG Tswen-Yung CHUANG Wen-Ssn LI Li HU Jianyu WANG Dongxiao | 2012 | Acta Oceanologica Sinica2012，31，2： | 15 |
| 11 | Multi-scale design and optimization for solid-lattice hybrid structures and their application to aerospace vehicle components显示文摘By integrating topology optimization and lattice-based optimization,a novel multi-scale design method is proposed to create solid-lattice hybrid structures and thus to improve the mechanical performance as well as reduce the structural weight.To achieve this purpose,a two-step procedure is developed to design and optimize the innovative structures.Initially,the classical topology optimization is utilized to find the optimal material layout and primary load carrying paths.Afterwards,the solid-lattice hybrid structures are reconstructed using the finite element mesh based modeling method.And lattice-based optimization is performed to obtain the optimal crosssection area of the lattice structures.Finally,two typical aerospace structures are optimized to demonstrate the effectiveness of the proposed optimization framework.The numerical results are quite encouraging since the solid-lattice hybrid structures obtained by the presented approach show remarkably improved performance when compared with traditional designs. | Chuang WANG Jihong ZHU Manqiao WU Jie HOU Han ZHOU Lu MENG Chenyang LI Weihong ZHANG | 2021 | Chinese Journal of Aeronautics2021，34，5： | 14 |
| 12 | The effects of simulated nitrogen deposition on extracellular enzyme activities of litter and soil among different-aged stands of larch显示文摘Aims Nitrogen(N)addition could affect the rate of forest litter and soil organic matter decomposition by regulating extracellular enzyme activity(EEa).The impact of N addition on EEa may differ across different age stands with different organic matter quality.We were interested in whether the impact of N addition on EEa in litter and mineral soil during the growing season was dependent on stand age of a larch plantation in North China.Methods We added three levels of N(0,20 and 50 kg N ha^(−1) year^(−1))in three age stands(11,20 and 45 years old)of Larix principis-rupprech-tii plantation in North China.We measured potential activities of β-1,4-glucosidase(b),cellobiohydrolase(Cb),β-1,4-N-acetyl-glucosaminidase(Nag)and phenol oxidase(Po)in litter(organic horizon)and mineral soil(0-10 cm)during the second growing sea-son after N amendment.We also measured C and N concentrations,microbial biomass C and N,and KCl-extractable ammonium and nitrate in both litter and mineral soil.Important Findings We observed unimodal patterns of EEa during the growing season in all three stands,consistent with the seasonal variations of soil temperature.stand age had a strong effect on EEa in both litter and mineral soil,and this effect differed between litter and mineral soil as well as between different enzymes.N addition did not significantly affect the activities of b or Cb but significantly suppressed the activity of Nag in litter.We also found stand age-specific responses of Po activity to N addition in both litter and mineral soil.N addition suppressed Po activity of the high C:N ratio litters in 20-and 45-year-old stands but had no significant effect on Po activity of the low C:N ratio litter in 11-year-old stand.moreover,N addition inhibited Po activity of the high C:N ratio soil in 20-year-old stand but had no significant impact on Po activity of the low C:N ratio soils in 11-and 45-year-old stands.overall,stand age had a greater effect on EEa in litter and mineral soil compared to 2 years of N addition.moreover,the effect of N addition on Po activity is stand age dependent,which may affect the long-term soil carbon storage in this forest. | Yuecun Ma Biao Zhu Zhenzhong Sun Chuang Zhao Yan Yang Shilong Piao | 2014 | Journal of Plant Ecology2014，7，3： | 14 |
| 13 | H_2S燃料电池用质子传导膜及电池性能显示文摘研究了H2S燃料电池用的质子传导膜的制备及性能,考察了不同的Li2SO4与填充物Al2O3的匹配、微量元素B(H2BO3)的掺杂对膜及电池性能影响.研究了由H2S、(MoS2+NiS)/Li2SO4-Al2O3/pt、air构成的燃料电池在101.13kPa和600~700℃C时的电化学特性.在实验温度范围内,质子传导膜Li2SO4-Al2O3及整个电池系统在H2S气流下具有较好的化学稳定性.温度提高,质子传导膜的内阻减小,膜及电池性能变好.微量元素B的掺杂提高了膜的机械强度及膜的致密性,从而改善了电池的性能.在实验条件下,较适宜的B的掺杂量为2%~5%(质量百分数),较适宜的Li2SO4:Al2O3(质量比)为(3~5):1,电池最大输出电流密度和功率密度在700℃时分别达到200mA.cm-2和55mW.cm-2. | 钟理 张腾云 WEI Guoling Chuang Karl | 2004 | 高校化学工程学报2004，18，2： | 14 |
| 14 | 中西医医学生在叙事医学上的不同视野显示文摘医学作为一种实践科学还是治疗艺术,在现在的医学界有广泛的争论。很多人认为,医学必须要求医生在自身建立叙事情感并且更深入地挖掘病人的内心。文中的调查研究活动以台湾某教学医院的学生为研究对象,开展叙事医学项目的系列活动,采用问卷调查和量表研究,并评估和比较了中西医学生对于叙事医学作为一种学习共情和医学专业精神的方法的不同认知。 | 张千会 周碧雯 Chien - Da Huang Kuo - Chen Liao Fu - Tsai Chuang | 2017 | 中国医学伦理学2017，30，10： | 14 |
| 15 | Rapid report of the 8 January 2022 M_(S)6.9 Menyuan earthquake,Qinghai,China显示文摘The M_(S)6.9 Menyuan earthquake in Qinghai Province,west China is the largest earthquake by far in 2022.The earthquake occurs in a tectonically active region,with a background b-value of 0.87 within 100 km of the epicenter that we derived from the unified catalog produced by China Earthquake Networks Center since late 2008.Field surveys have revealed surface ruptures extending 22 km along strike,with a maximum ground displacement of 2.1 m.We construct a finite fault model with constraints from In SAR observations,which showed multiple fault segments during the Menyuan earthquake.The major slip asperity is confined within 10 km at depth,with the maximum slip of 3.5 m.Near real-time back-projection results of coseismic radiation indicate a northwest propagating rupture that lasted for~10 s.Intensity estimates from the back-projection results show up to a Mercalli scale of IX near the ruptured area,consistent with instrumental measurements and the observations from the field surveys.Aftershock locations(up to January 21,2022)exhibit two segments,extending to~20 km in depth.The largest one reaches M_(S)5.3,locating near the eastern end of the aftershock zone.Although the location and the approximate magnitude of the mainshock had been indicated by previous studies based on paleoearthquake records and seismic gap,as well as estimated stressing rate on faults,significant surfacebreaching rupture leads to severe damage of the high-speed railway system,which poses a challenge in accurately assessing earthquake hazards and risks,and thus demands further investigations of the rupture behaviors for crustal earthquakes. | Hongfeng Yang Dun Wang Rumeng Guo Mengyu Xie Yang Zang Yue Wang Qiang Yao Chuang Cheng Yanru An Yingying Zhang | 2022 | Earthquake Research Advances2022，2，1： | 14 |
| 16 | Eradication of Helicobacter pylori increases childhood growth and serum acylated ghrelin levels显示文摘AIM: To determine whether Helicobacter pylori (H. pylori)infected children have reduced body weight (BW) and height (BH) growth, and if H. pylori eradication may restore growth while improving serum acylated ghrelin. METHODS: This longitudinal cohort study with oneyear follow-up enrolled 1222 children aged 4 to 12 years old into an observation cohort (18 with and 318 without H. pylori ) and intervention cohort (75 with and 811 without). The 7-d triple therapy was used for eradication in the intervention cohort. The net increases of BW and BH as well serum acylated ghrelin after oneyear follow-up were compared between successful eradicated H. pylori-infected children and controls. RESULTS: In the observation cohort, the H. pylori - infected children had lower z score of BW (-1.11 ± 0.47 vs 0.35 ± 0.69, P = 0.01) and body mass index (BMI) (0.06 ± 0.45 vs 0.44 ± 0.73, P = 0.02) at enrollment and lower net BW gain after one-year follow-up (3.3 ± 2.1 kg vs 4.5 ± 2.4 kg, P = 0.04) than the non-infected controls. In the intervention cohort, the H. pylori - infected children had lower z score of BMI (0.25 ± 1.09 vs 0.68 ± 0.87, P = 0.009) and serum acylated ghrelin levels (41.8 ± 35.6 pg/mL vs 83.6 ± 24.2 pg/mL, P < 0.001) than the non-infected controls. In addition to restoring decreased serum ghrelin levels (87.7 ± 38.0 pg/mL vs 44.2 ± 39.0 pg/mL, P < 0.001), the H. pylori - infected children with successful eradication had higher net gains (P < 0.05) and increase of z scores (P < 0.05) of both BW and BH as compared with non-infected controls after one-year follow-up. CONCLUSION:H. pylori-infected children are associated with low serum acylated ghrelin and growth retardation. Successful eradication of H. pylori restores ghrelin levels and increases growth in children. | Yao-Jong Yang Bor-Shyang Sheu Hsiao-Bai Yang Cheng-Chan Lu Ching-Chun Chuang | 2012 | World Journal of Gastroenterology2012，18，21： | 12 |
| 17 | Silicon assistant carbothermal reduction for SiC powders显示文摘The silicon assistant method to increase the reaction yield of carbothermal reduction of silica at a lower temperature is reported. The effect of silicon on the carbothermal reduction process has been investigated in detail. Compared with traditional reduction, the introduction of silicon can change the reaction path and further increase the conversion of silicon carbide at a lower temperature. It is considered that the assistant reduction consists of three steps: vaporizing and melting of silicon, formation of silicon monoxide, and synthesis of silicon carbide. The morphology of the synthesized SiC powders through the silicon assistant method can be affected apparently by the experimental temperature. | Kezhi Li Jian Wei Hejun Li Chuang Wang Gengsheng Jiao | 2008 | Journal of University of Science and Technology Beijing2008，15，4： | 12 |
| 18 | Anti-oxidant and anti-inflammatory effects of hydrogenrich water alleviate ethanol-induced fatty liver in mice显示文摘AIM To investigate the effects of hydrogen-rich water(HRW) treatment on prevention of ethanol(Et OH)-induced early fatty liver in mice.METHODS In vitro reduction of hydrogen peroxide by HRW was determined with a chemiluminescence system. Female mice were randomly divided into five groups: control,Et OH,Et OH + silymarin,Et OH + HRW and Et OH + silymarin + HRW. Each group was fed a Lieber-De Carli liquid diet containing Et OH or isocaloric maltose dextrin(control diet). Silymarin was used as a positive control to compare HRW efficacy against chronic Et OH-induced hepatotoxicity. HRW was freshly prepared and given at a dosage of 1.2 m L/mouse trice daily. Blood and liver tissue were collected after chronic-binge liquid-diet feeding for 12 wk.RESULTS The in vitro study showed that HRW directly scavenged hydrogen peroxide. The in vivo study showed that HRW increased expression of acyl ghrelin,which was correlated with food intake. HRW treatment significantly reduced Et OH-induced increases in serum alanine aminotransferase,aspartate aminotransferase,triglycerol and total cholesterol levels,hepatic lipid accumulation and inflammatory cytokines,including tumor necrosis factor-alpha(TNF-α) and interleukin(IL)-6. HRW attenuated malondialdehyde level,restored glutathione depletion and increased superoxide dismutase,glutathione peroxidase and catalase activities in the liver. Moreover,HRW reduced TNF-α and IL-6 levels but increased IL-10 and IL-22 levels.CONCLUSION HRW protects against chronic Et OH-induced liver injury,possibly by inducing acyl ghrelin to suppress the pro-inflammatory cytokines TNF-α and IL-6 and induce IL-10 and IL-22,thus activating antioxidant enzymes against oxidative stress. | Ching-Pin Lin Wen-Chen Chuang Fung-Jou Lu Chih-Yen Chen | 2017 | World Journal of Gastroenterology2017，23，27： | 12 |
| 19 | 晚期卵巢癌、输卵管癌及原发性腹膜癌腹腔镜肿瘤细胞减灭术的安全性及有效性研究显示文摘目的总结晚期卵巢癌、输卵管癌和腹膜癌患者行腹腔镜初次或间歇性肿瘤细胞减灭术的临床经验。方法回顾分析接受腹腔镜肿瘤细胞减灭术的晚期卵巢癌(FIGOⅡc期以上)、输卵管癌和原发性腹膜癌患者临床资料。结果 32名患者接受腹腔镜评估手术。17例接受全腹腔镜肿瘤细胞减灭术,其中88.2%为满意的肿瘤细胞减灭术;11例腹腔镜评估后转开腹肿瘤细胞减灭术,其中72.7%为满意的肿瘤细胞减灭术;4例仅进行活检和(或)姑息手术。腹腔镜组平均随访时间19.7月9,例无瘤生存6,例带瘤生存2,例因肿瘤死亡。开腹组平均随访时间25.8月,3例无瘤生存,5例带瘤生存,3例因肿瘤死亡。腹腔镜组术中失血量较少,术后住院时间较短(P=0.008和P=0.03),但手术时间及并发症发生率与开腹组相比无统计学差异。中位复发时间,腹腔镜组为31.7月,开腹组为21.5个月(P=0.3)。结论对于经过精心挑选的晚期卵巢癌、输卵管癌和原发性腹膜癌病例,采用腹腔镜进行诊断、分期和肿瘤细胞减灭术,在技术上是可行的。 | 李萌 熊光武 Farr R.Nezhat Shaghayegh M.DeNoble Connie S.Liu Jennifer E.Cho Douglas N.Brown Linus Chuang Herbert Gretz Prakash Saharia | 2012 | 中国微创外科杂志2012，12，2： | 11 |
| 20 | Assessment of Waterlogging Risk in Lixiahe Region of Jiangsu Province Based on AVHRR and MODIS Image显示文摘Four images of 1991 AVHRR, 2003 and 2007 MODIS were used to extract waterlogging inundated water of three years, and three inundated water maps were overlaid to estimate waterlogging affected frequency. Based on wa-terlogging affected frequency, waterlogging hazard of pixel scale was assessed. According to the weighed score of area percentage of different waterlogging affected frequency in 13 counties/cities of Lixiahe region, waterlogging hazard rank of every county/city was assessed. Waterlogging affected frequency map and 1km×1km grid landuse map were used to assess waterlogging risk of pixel scale; and then waterlogging risk rank of every county/city was assessed by the similar method by which waterlogging hazard rank of every county/city was assessed. High risk region is located mainly in core zone of Lixiahe hinterland, medium risk region is adjacent to high risk region, and low risk region is located in the most outlying area of risk zone and mainly in south to middle part of Lixiahe region. Xinghua and Gaoyou belong to high risk city, Jiangyan belongs to medium risk city, and the other counties/cities have low or lower waterlogging risk. The method of assessing waterlogging risk in this paper is simple and applicable. This paper can provide guidance for the waterlogging risk analysis in broader area of Huaihe River Basin. | HUANG Dapeng LIU Chuang FANG Huajun PENG Shunfeng | 2008 | Chinese Geographical Science2008，18，2： | 11 |
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