|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effects of external stress on biodegradable orthopedic materials: A review显示文摘Biodegradable orthopedic materials(BOMs)are used in rehabilitation and reconstruction of fractured tissues.The response of BOMs to the combined action of physiological stress and corrosion is an important issue in vivo since stress-assisted degradation and cracking are common.Although the degradation behavior and kinetics of BOMs have been investigated under static conditions,stress effects can be very serious and even fatal in the dynamic physiological environment.Since stress is unavoidable in biomedical applications of BOMs,recent work has focused on the evaluation and prediction of the properties of BOMs under stress in corrosive media.This article reviews recent progress in this important area focusing on biodegradable metals,polymers,and ceramics. | Xuan Li Chenglin Chu Paul K.Chu | 2016 | Bioactive Materials2016，1，1： | 5 |
| 2 | Insights into self-healing behavior and mechanism of dicalcium phosphate dihydrate coating on biomedical Mg显示文摘Self-healing coatings have been developed as smart surface coatings for Mg and its alloys to retain local corrosion from the coating damages.In this study,we prepared dicalcium phosphate dihydrate(DCPD)coating on biomedical Mg,and found that the artificial scratches in DCPD coating can be efficiently sealed by anti-corrosive products in both Hank's and normal saline(NS)solutions.Besides,the in-depth study revealed that DCPD was served as not only a physical barrier but also a self-healing agent,demonstrating an autonomous self-healing coating without embedded extra corrosion inhibitors.Moreover,Hank's solution provided foreign-aid filmforming ions to promote self-healing behavior.The findings might offer new opportunities for further studies and applications of efficient self-healing coatings on biodegradable Mg implants. | Qiangsheng Dong Xingxing Zhou Yuanjia Feng Kun Qian Huan Liu Mengmeng Lu Chenglin Chu Feng Xue Jing Bai | 2021 | Bioactive Materials2021，6，1： | 4 |
| 3 | Preparation, microstructure and degradation performance of biomedical magnesium alloy fine wires显示文摘With the development of new biodegradable Mg alloy implant devices, the potential applications of biomedical Mg alloy fine wires are realized and explored gradually. In this study, we prepared three kinds of Mg alloy fine wires containing 4 wt% RE(Gd/Y/Nd) and 0.4 wt% Zn with the diameter less than 0.4 μm through casting, hot extruding and multi-pass cold drawing combined with intermediated annealing process. Their microstructures, mechanical and degradation properties were investigated. In comparison with the corresponding as-extruded alloy, the final fine wire has significantly refined grain with an average size of 3–4 μm, and meanwhile shows higher yield strength but lower ductility at room temperature. The degradation tests results and surface morphologies observations indicate that Mg–4Gd–0.4Zn and Mg–4Nd–0.4Zn fine wires have similar good corrosion resistance and the uniform corrosion behavior in SBF solution. By contrast, Mg–4Y–0.4Zn fine wire shows a poor corrosion resistance and the pitting corrosion behavior. | Jing Bai Lingling Yin Ye Lu Yiwei Gan Feng Xue Chenglin Chu Jingli Yan Kai Yan Xiaofeng Wan Zhejun Tang | 2014 | Progress in Natural Science:Materials International2014，24，5： | 3 |
| 4 | PREPARATION OF TiNi SHAPE MEMORY ALLOY POROSINT BY SHS显示文摘PREPARATIONOFTiNiSHAPEMEMORYALLOYPOROSINTBYSHS①ChuChenglin,LiBo,WangShidong,ZhangShuge,YangXiaoxi,YinZhongdaBox4... | Chu Chenglin *, Li Bo ** , Wang Shidong ** , Zhang Shuge *** , Yang Xiaoxi *** , Yin Zhongda * * Box 433, School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001 ** Analysis and Testing Center | 1997 | 中国有色金属学会会刊:英文版1997，7，4： | 3 |
| 5 | The effect of enzymes on the in vitro degradation behavior of Mg alloy wires in simulated gastric fluid and intestinal fluid显示文摘With an upsurge of biodegradable metal implants,the research and application of Mg alloys in the gastrointestinal environment of the digestive tract have been of great interest.Digestive enzymes,mainly pepsin in the stomach and pancreatin in the small intestine,are widespread in the gastrointestinal tract,but their effect on the degradation of Mg alloys has not been well understood.In this study,we investigated the impacts of pepsin and pancreatin on the degradation of Mg-2Zn alloy wires.The results showed that the pepsin and pancreatin had completely different even the opposite effects on the degradation of Mg,although they both affected the degradation product layer.The degradation rate of Mg wire declined with the addition of pepsin in simulated gastric fluid(SGF)but rose with the addition of pancreatin in simulated intestinal fluid(SIF).The opposite trends in degradation rate also resulted in completely different degradation morphologies in wires surface,where the pitting corrosion in SGF was inhibited because of the physical barrier effect of pepsin adsorption.In contrast,the adsorption of pancreatin affected the integrity of magnesium hydrogen phosphate film,causing a relatively uneven degraded surface.These results may help us to understand the role of different digestive enzymes in the degradation of magnesium and facilitate the development and clinical application of magnesium alloy implanted devices for the digestive tract. | Yue Zhang Jian Cao Xianli Wang Huan Liu Yi Shao Chenglin Chu Feng Xue Jing Bai | 2022 | Bioactive Materials2022，7，1： | 2 |
| 6 | 3D-cubic interconnected porous Mg-based scaffolds for bone repair显示文摘Mg-based porous materials,as potential bone tissue engineering scaffolds,are considered an attractive strategy for bone repair owing to favorable biodegradability,good biocompatibility and suitable mechanical properties.In this work,3D-cubic interconnected porous Mg–xZn–0.3Ca(x=0,3,6)scaffolds were prepared to obtain desirable pore structures with a mean porosity up to 73%and main pore size of 400–500μm,which pore structures were close to the human cancellous bone.The structure–property relationships in the present scaffolds were analyzed by experiments and theoretical models of generalized method of cells(GMC).Mg–xZn–0.3Ca scaffolds exhibited good compression properties with a maximum above 5MPa in yield strength and about 0.4GPa in elastic modulus.This was attributed to not only the alloy strengthening but also the large minimum solid area.On the other hand,the scaffolds showed undesirable and relatively serious degradation behavior in Hank’s solution,resulting from Zn addition in Mg-based scaffolds and the high surface area ratio in the pore structure.Therefore,surface modifications are worth studying for controlled degradation in the future.In conclusion,this research would explore a novel attempt to introduce 3D-cubic pore structure for Mg-based scaffolds,and provide new insights into the preparations of Mg-based scaffolds with good service performances for bone repair. | Qiangsheng Dong Yang Li Huiqin Jiang Xingxing Zhou Huan Liu Mengmeng Lu Chenglin Chu Feng Xue Jing Bai | 2021 | Journal of Magnesium and Alloys2021，9，4： | 2 |
| 7 | The effect of pore size and porosity of Ti6Al4V scaffolds on MC3T3-E1 cells and tissue in rabbits显示文摘Electron beam melting(EBM) allows the fabrication of specific porous titanium implants, whereas their in vitro and in vivo biological performance should be further investigated. In this study, we examined the porous Ti6 Al4 V scaffolds(low, 334.1 μm pore size with 55.4% porosity;middle, 383.2 μm pore size with 65.2% porosity;and high, 401.6 μm pore size with 78.1%porosity) fabricated through EBM. The structural characterization and mechanical properties of porous Ti6 Al4 V scaffolds were measured through micro-computed tomography(micro-CT), scanning electron microscopy, and a material testing system.MC3 T3-E1 cells were used to assess the proliferation and differentiation of the cells on different scaffolds at day 7 and day 14 based on the expression levels of genes, including alkaline phosphatase, bone morphogenetic protein-2, osteopontin and runtrelated transcription factor-2. Rabbits with distal femoral defects were utilized to evaluate bone ingrowth in the porous titanium.All of the samples were subjected to micro-CT and histological analysis after 12 weeks. Results showed that compressive Young’s modulus of 0.3–1.1 GPa was similar to the trabecular bone. The three types of porous Ti6 Al4 V scaffolds were inclined to promote cell proliferation, whereas cell differentiation and bone ingrowth into the porous scaffolds were biased to the porous titanium with relatively large pores and porosity(middle and high). This study implied that the present porous implant design,which had the combined advantages of different pore sizes and porosity, might be meaningful and promising for trabecular bone defect restoration. | LUAN HuiQin WANG LiTing REN WeiYan CHU Zhao Wei HUANG YunFei LU ChengLin FAN YuBo | 2019 | Science China(Technological Sciences)2019，62，7： | 2 |
| 8 | Cavitation erosion characteristics of a Fe-Cr-Si-B-Mn coating fabricated by high velocity oxy-fuel (HVOF) thermal spray显示文摘 | Wu Yuping Lin Pinghua Chu Chenglin | 2012 | Materials and Corrosion2012，63，8： | 1 |
| 9 | Effect of equal channel angular pressing and heat treatment on the microstructure of Cu-Al-Be-B shape memory alloy显示文摘 | Zhang Ping Ma Aibin Lu Sheng Chenglin Chu | 2009 | Materials Letters2009，63，： | 1 |
| 10 | Hydroxyapatite-Ti functionally graded biomaterial fabricated by powder metallurgy 显示文摘 | Chu Chenglin Zhu Jingchuan Yin Zhongda | 1999 | Materials Science and Engineering: A1999，271，12： | 1 |
| 11 | Hydroxyapatite-Ti functionally graded biomaterial fabricated by powder metallurgy显示文摘 | Chu Chenglin Zhu Jingchuan Yin Zhongda | | 0，，： | 1 |
| 12 | Cavitation erosion characteristics of a Fe–Cr–Si–B–Mn coating fabricated by high velocity oxy-fuel (HVOF) thermal spray显示文摘 | Wu Yuping Lin Pinghua Chu Chenglin Wang Zehua Cao Ming Hu Junhua | 2006 | Materials Letters2006，，8： | 1 |
| 13 | Rare Metal Materials and Engineering显示文摘 | Wang Hongxing Li Yingguang Chu Chenglin | 2011 | 40(2):3162011，40，2： | 1 |
| 14 | Impact behaviors of poly-lactic acid based biocomposite reinforced with unidirectional high-strength magnesium alloy wires显示文摘A novel poly-lactic acid(PLA) based biocomposite reinforced with unidirectional high-strength magnesium alloy(Mg-alloy) wires for bone fracture fixation was fabricated by hot-compressing process. The macroscopical and microscopical impact behaviors of the biocomposite were investigated using impact experiments and finite element method(FEM), respectively. The results indicated that the biocomposite had favorable impact properties due to the plastic deformation behavior of Mg-alloy wires during impact process. While the content of Mg-alloy wires reached20 vol%, the impact strength of the composite could achieve 93.4 k J/m2, which is approximate 16 times larger than that of pure PLA fabricated by the same process. According to FEM simulation results, the complete destruction life of the composites during impact process increased with increasing volume fraction of Mg-alloy wires, indicating a high impact-bearing ability of the composite for bone fracture fixation.Simultaneously, the energy absorbed by Mg-alloy wires in the composites had a corresponding increase. In addition, it denoted that the impact properties of the composites are sensitive to the initial properties of the matrix material. | Xuan Li Chao Guo Xiaokai Liu Lei Liu Jing Bai Feng Xue Pinghua Lin Chenglin Chu | 2014 | Progress in Natural Science:Materials International2014，24，5： | 1 |
| 15 | Hy- droxyapatite-Ti functionally graded biomaterial fabricated by powder metallurgy显示文摘 | Chu Chenglin Zhu Jingchuan Yin Zhongda | 1999 | Materials Science and Engineer- ing A1999，271，12： | 1 |
| 16 | Cavitation erosion char- aeteristies of a Fe-Cr-Si-B-Mn coating fabricated by high velocity oxy-fuel(HVOF) thermal spray 显示文摘 | Wu ~uping Lin Pinghua Chu Chenglin | 2007 | Materials Letters2007，61，： | 1 |
| 17 | Cavitation erosion characteristics of a Fe-Cr-Ni-Si-B-Mn coating fabricated by high velocity oxy-fuel(HVOF) thermal spray显示文摘 | Wu Yuping Lin Pinghua Chu Chenglin | 2007 | Materials Letters2007，61，： | 1 |
| 18 | Cavitation erosion characteristics of a Fe-Cr-Si-B-Mn coating fabricated by high velocity oxy- fuel (HVOF) thermal spray显示文摘 | Wu Yuping Lin Pinghua Chu Chenglin | 2007 | Materials Letters2007，61，： | 1 |
| 19 | Cavitation erosion characteristics of a Fe-Cr-Si-B-Mn coating fabricated by high velocity oxy-fuel (HVOF) thermal spray显示文摘 | Wu Yuping Lin Pinghua Chu Chenglin | 2007 | Materials Letters2007，61，89： | 1 |
| 20 | The influence of alternating cyclic dynamic loads with different low frequencies on the bio-corrosion behaviors of AZ31B magnesium alloy in vitro显示文摘The real physiological environment of human body is complicated with different degrees and forms of dynamic loads applied to implanted medical devices due to the daily activities of the patients,which would have impacts on the degradation behaviors of magnesium alloy implants.In this work,the bio-corrosion behaviors of AZ31B magnesium alloy under alternating cyclic dynamic loads with different low frequencies(0.1-2.5 Hz)were specially investigated.It was found that the bio-degradation performances under external dynamic stressed conditions were much severer than those under unstressed conditions and static loads.The corrosion rates were generally accelerated as the rise of cyclic frequency.Hereby a numerical model for the degradation process of Mg alloy was established.The corrosion current density icorr of Mg alloy and the applied loading frequency f matches a linear relationship of ln icorr∝f,which is the result of interactions between the cyclic alternating load and corrosive environment.This work could provide a theoretical reference and an experimental basis for further researches on the biodegradation behaviors of biomedical materials under dynamic conditions. | Linyuan Han Zhenwei Zhang Jianwei Dai Xuan Li Jing Bai Zhihai Huang Chao Guo Feng Xue Chenglin Chu | 2022 | Bioactive Materials2022，7，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员