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| 1 | Cholangiocarcinoma:principles and current trends显示文摘BACKGROUND:Cholangiocarcinoma(CCA)is a lethal cancer of the biliary epithelium,originating from the liver(intrahepatic),at the confluence of the right and left hepatic ducts(hilar)or in the extrahepatic bile ducts.It is a rare malignancy associated with poor prognosis.DATA SOURCES:We searched the PubMed/MEDLINE database for relevant articles published from 1989 to 2008.The search terms used were related to 'cholangiocarcinoma' and its ' treatment'.Although no language restrictions were imposed initially,for the full-text review and final analysis,our resources only permitted the review of articles published in English.This review deals with the treatment of cholangiocarcinoma,the principles and the current trends.RESULTS:The risks and prognostic factors,symptoms and differential diagnosis are thoroughly discussed.In addition,the tools of preoperative diagnosis such as endoscopic retrograde cholangiopancreatography,digital image analysis,fluorescence in situ hybridization and magnetic resonance cholangiopancreatography are reviewed.Moreover,the treatment of CCA is discussed.CONCLUSIONS:The only curative treatment available is surgical management.Unfortunately,many patients present with unresectable tumors,the majority of whom die within a year of diagnosis.Surgical treatment involves major resections of the liver,pancreas and bile duct,with considerable mortality and morbidity.However,in selected cases and where indicated,appropriate management with aggressive surgery may achieve a good outcome with a prolonged survival expectancy. | George N Zografos Athanasios Farfaras Flora Zagouri Dimosthenis Chrysikos Kostas Karaliotas | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，1： | 14 |
| 2 | Association of Helicobacter Pylori Infection and Colon Cancer显示文摘 | Alexandros Strofilas Emmanuel E Lagoudianakis Charalambos Seretis Apostolos Pappas Nikolaos Koronakis Dimitrios Keramidaris Ilias Koukoutsis Ioannis Chrysikos Ioannis Manouras Andreas Manouras | 2012 | Journal of Clinical Medicine Research2012，，3： | 2 |
| 3 | /T$显示文摘 | Andreas Arvanitoyeorgos Ioannis Chrysikos Yusuke Sakane | 2013 | Proceedings of the American Mathematical Society2013，，7： | 1 |
| 4 | Flag manifolds, symmetric t -triples and Einstein metrics显示文摘 | Ioannis Chrysikos | 2012 | Differential Geometry and its Applications2012，，6： | 1 |
| 5 | Invariant Einstein metrics on flag manifolds with four isotropy summands显示文摘 | Andreas Arvanitoyeorgos Ioannis Chrysikos | 2010 | Annals of Global Analysis and Geometry2010，，2： | 1 |
| 6 | Trastuzumab administration during pregnancy: a syslematie review and meta- analysis显示文摘 | Zagnuri F Sergentanis TN Chrysikos D | 2013 | Breast Cancer Res Treat2013，137，2： | 1 |
| 7 | Platinum derivatives during pregnancy in cervical cancer: a systematic review and meta-analysis 显示文摘 | Zagouri F Sergentanis TN Chrysikos D | 2013 | Obstet Gynecol2013，121，21： | 1 |
| 8 | Platinum derivatives during pregnancy in cervical cancer:a systematic review and meta-analysis显示文摘 | Zagouri F Sergentanis TN Chrysikos D | | 0，，2： | 1 |
| 9 | HspgO inhib- itors in breast cancer~ a systematic review显示文摘 | Zagouri F Sergentanis T N Chrysikos D etal | 2013 | Breast2013，22，5： | 1 |
| 10 | Taxanes for breast cancer during pregnancy: a systematic review 显示文摘 | Zagouri F Sergentanis TN Chrysikos D | 2013 | Clin Breast Cancer2013，13，1： | 1 |
| 11 | Trastuzumab admin- istration during pregnancy: a systematic review and meta-analysis 显示文摘 | Zagouri F Sergentanis TN Chrysikos D | 2013 | Breast Cancer Res Treat2013，137，2： | 1 |
| 12 | Trastu- zumab administration during pregnancy: a systematic review and meta-analysis显示文摘 | Zagouri F Sergentanis TN Chrysikos D | 2013 | Breast Cancer Res Treat2013，137，2： | 1 |
| 13 | Taxanes for breast cancer during pregnancy: a systematic review 显示文摘 | Zagouri F Sergentanis TN Chrysikos D | 2013 | Clin Breast Cancer2013，13，1： | 1 |
| 14 | Invariant Einstein metrics on generalized flag manifolds with four isot- ropy summands 显示文摘 | Arvanitoyeorgos A Chrysikos I | 2010 | Ann Glob Anal Geom2010，37，： | 1 |
| 15 | Trastuzumab adrdnistration during pregnaney: a systematic review and meta-analysis显示文摘 | Zagomi F Sergentanis TN Chrysikos D | 2013 | Breast Cancer Res Treat2013，137，2： | 1 |
| 16 | Flag manifolds, symmetric t -triples and Einstein metrics 显示文摘 | Chrysikos I | 2010 | Ann Glob Anal Geom2010，，： | 1 |
| 17 | Platinumderivatives during pregnancy in cervical cancer : a systematicreview and meta-analysis 显示文摘 | Zagouri F Sergentanis TN Chrysikos D | 2013 | Obstet Gynecol2013，12，2： | 1 |
| 18 | Platinum derivatives dur- ing pregnancy in cervical cancer:a systematic review and meta-analy- sis显示文摘 | Zagouri F Sergentanis T Chrysikos D | 2013 | Obstet Gyneco12013，121，21： | 1 |
| 19 | Invariant Einstein metrics on generalized flag manifolds with four isotropy summands显示文摘 | Arvanitoyeorgos A Chrysikos I | 2010 | Ann Glob Anal Geom2010，37，： | 1 |
| 20 | Complete description of invariant Einstein metrics on the generalized flag man ifold SO(2n)/ U(p) X U(n p) 显示文摘 | Arvanitoyeorgos A Chrysikos I Sakane Y | 2010 | Ann Glob Anal Geom2010，38，4： | 1 |
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