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| 1 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 2 | 血压控制良好的老年高血压患者血压变异性与认知功能的关系显示文摘尽管已知较高血压和血压变异性与认知功能损害有关,但关于血压控制良好的老年患者血压变异性与认知功能之间的关系的数据仍旧很少。方法:本研究纳入伴有一种或多种心血管病危险因素的门诊老年高血压患者232例进行分析。所有患者进行动态血压监测和日本版的蒙特利尔认知功能评估(Montreal cognitiveassessment,MoCA-J )量表测试。 | Cho N Hoshide S Nishizawa M Fujiwara T Kario K 陈云 叶鹏 | 2019 | 中华高血压杂志2019，27，2： | 4 |
| 3 | Toxicity and Carcinogenicity of Ozone in Combination with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and Dibutyl Phthalate in B6C3F1 Mice for 16 and 32 Weeks显示文摘To evaluate the toxic and carcinogenic potential of ozone alone or in combination with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone(NNK) and/or dibutyl phthalate(DBP).Methods Male and female B6C3F1 mice were exposed,through inhalation,intravenous administration and diet,to 0.5 ppm of ozone,1.0 mg/kg of NNK and 5000 ppm of DBP,individually and in combination for 16 and 32 weeks.Results No treatment-related death was seen,but significant differences in body and organ weights between control and treated mice were observed during the study.No incidence of lung tumor incidence was recorded in mice exposed to either ozone alone or combined treatment.Oviductal carcinomas were observed in female mice exposed to ozone or DBP alone for 16 weeks and ozone in combination with NNK and DBP for 32 weeks.Conclusion Although ozone alone and in conjunction with NNK and/or DBP does not induce lung cancer under our experimental conditions,they induce oviductal carcinomas in B6C3F1 mice. | MIN YOUNG KIM M YUNG CHO | 2009 | Biomedical and Environmental Sciences2009，22，3： | 3 |
| 4 | Existence and design of observer for nonlinear systems: relation to distance to unobservability显示文摘 | Rajamani R Cho Y M | 1998 | International Journal of Control1998，69，5： | 2 |
| 5 | Corrosion properties of oxide dispersion strengthened steels in super-critical water environment显示文摘 | H.S Cho A Kimura S Ukai M Fujiwara | 2004 | Journal of Nuclear Materials2004，，： | 2 |
| 6 | Damage identification in beam-type structures: frequency-based method vs mode-shape-based method 显示文摘 | Kim J T Ryu Y S Cho H M | 2003 | Engineering Structures2003，25，1： | 2 |
| 7 | 显示文摘 | Cho W S Yoshimura M | 1997 | Eur J solid State Inorg Chem1997，34，9： | 1 |
| 8 | Dispersion polymerization of acrylamide with quaternary ammonium cationic comonomer in aqueous solution显示文摘 | Song B K Cho M S Yoon K J | 2003 | J Appl Polym Sci2003，87，： | 1 |
| 9 | Periodic mesoporous organosilicas with multiple bridging groups and spherical morphology显示文摘 | CHO E B KIM D JARONIEC M | 2007 | Langmuir2007，23，11： | 1 |
| 10 | An alternative altered cast technique for a distal extension removable partial denture显示文摘 | Landesman M Adomian JG | 1997 | J Calif Dent Assoc1997，25，5： | 1 |
| 11 | Processing optimization and functional properties of gelatin from shark (Isurus oxyrinchus ) cartilage显示文摘 | CHO S M KWAK K S PARK D C | 2004 | Food Hydrocolloids2004，18，： | 1 |
| 12 | Chemical profiling and expression profiling during the manufacturing process of Talwan oolong tea 'Oriental Beauty'显示文摘 | CHO J Y MIZUTANI M SHIMIZU B I | 2007 | Bioscience Biotechnology and Biochemistry2007，71，6： | 1 |
| 13 | Salicornia herbacea:Botanical, Chemical and parmacological review of halophyte marsh plant 显示文摘 | Rhee M H Park H J Cho J Y | 2009 | Journal of Medicinal Plants Research2009，3，8： | 1 |
| 14 | The placebo response in the treatment of chronic fatigue syndrome: a systematic review and meta-analysis 显示文摘 | Cho H J Hotopf M Wessely S | 2005 | Psychosom Med2005，67，2： | 1 |
| 15 | Computational Implemen- tation of Asymmetric Integral Imaging by Use of Two Crossed Lenticular Sheets显示文摘 | Shin D H Cho M Kim E S | 2005 | ETRI J2005，27，： | 1 |
| 16 | Decomposition of volatile organic compounds and nitric oxide by non thermal plasma discharge process显示文摘 | Mok Y S Nam C M Cho M H | 2002 | IEEE Transaction on Plasma Science2002，30，1： | 1 |
| 17 | Acoustic emission source analysis of plasma sprayed thermal barrier coatings during four-point bend tests 显示文摘 | Ma X Q Cho S Takemoto M | 2001 | Surface and Coatings Technology2001，139，： | 1 |
| 18 | Antifibrotic effect of silymarin in rat secondary biliary fibrosis is mediated by downregulation of procollagen alpha 1and TIMP- 1显示文摘 | Jia JD Bauer M Cho JJ | 2001 | J Hepatol2001，35，： | 1 |
| 19 | Closed-Form Optimal Guidance Law for Missiles of Time-Varying Velocity 显示文摘 | Cho H J Ryoo C K Tahk M J | 1996 | Journal of Guidance Control and Dynamics1996，19，5： | 1 |
| 20 | Identification and classification of S haplotypes in Raphanus sativus by PCR-RFLP of the S locus glycoprotein (SLG) gene and the S locus receptor kinase (SRK) gene显示文摘 | Lim S H Cho H J Lee S J Hiderki M | 2002 | Plant Cell2002，104，： | 1 |
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