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| 1 | Disabling portosystemic encephalopathy in a non-cirrhotic patient: successful endovascular treatment of a giant inferior mesenteric-caval shunt via the left internal iliac vein显示文摘Hepatic encephalopathy is suspected in non-cirrhotic cases of encephalopathy because the symptoms are accompanied by hyperammonaemia. Some cases have been misdiagnosed as psychiatric diseases and consequently patients hospitalized in psychiatric institutions or geriatric facilities. Therefore, the importance of accurate diagnosis of this disease should be strongly emphasized. A 68-year-old female patient presented to the Emergency Room with confusion, lethargy, nausea and vomiting. Examination disclosed normal vital signs. Neurological examination revealed a minimally responsive woman without apparent focal deficits and normal reflexes. She had no history of hematologic disorders or alcohol abuse. Her brain TC did not demonstrate any intracranial abnormalities and electroencephalography did not reveal any subclinical epileptiform discharges. Her ammonia level was > 400 mg/d L(reference range < 75 mg/d L) while hepatitis viral markers were negative. The patient was started on lactulose, rifaximin and low-protein diet.On the basis of the doppler ultrasound and abdomen computed tomography angiography findings, the decision was made to attempt portal venography which confirmed the presence of a giant portal-systemic venous shunt. Therefore, mechanic obliteration of shunt by interventional radiology was performed. As a consequence, mesenteric venous blood returned to hepatopetally flow into the liver, metabolic detoxification of ammonia increased and hepatic encephalopathy subsided. It is crucial that physicians immediately recognize the presence of non-cirrhotic encephalopathy, in view of the potential therapeutic resolution after accurate diagnosis and appropriate treatments. | Luca de Martinis Gloria Groppelli Riccardo Corti Lorenzo Paolo Moramarco Pietro Quaretti Pasquale De Cata Mario Rotondi Luca Chiovato | 2017 | World Journal of Gastroenterology2017，23，47： | 3 |
| 2 | The genetics of Hashimoto's disease显示文摘 | Barbesino G Chiovato L | 2000 | Endocrinol Metab Clin North Am 2000 Jun2000，29，2： | 1 |
| 3 | Role of conventional ultrasonography and color flow-Doppler sonography in predicting malignancy in 'cold' thyroid nodules 显示文摘 | Rago T Vitti P Chiovato L | 1998 | Eur J Endocrinol1998，138，： | 1 |
| 4 | Role of chemokines in endocrine autoimmune diseases 显示文摘 | Rotondi M Chiovato L Romagnani S | 2007 | Endocr Rev2007，28，5： | 1 |
| 5 | Role of conventional ultrasonography and color flow-Doppler sonography in predicting malignancy in 'cold' thyroid nodules显示文摘 | Rago T Vitti P Chiovato L | 1998 | Eur J Endocrinol1998，138，： | 1 |
| 6 | L-thyroxine therapy induces a fall of thyroid microsomal and thyroglobulin antibodies in idiopathic myxedema and in hypothyroid, but not in euthyroid Hashimoto' s thyroiditis显示文摘 | Chiovato L Marcocci C Mariotti S | 1986 | J Endocrinol Invest1986，9，： | 1 |
| 7 | The effects of amiodarone on the thyroid 显示文摘 | Chiovato L Martino E Tonacchera M | 1994 | Elutocrinlolgy1994，143，： | 1 |
| 8 | Role of chemokines in endocrine autoimmune diseases显示文摘 | Rotondi M Chiovato L Romagnani S | 2007 | Endocr Rev2007，28，： | 1 |
| 9 | Risk of coronary heart diseaseand mortality for adults with subclinical hypothyroidism显示文摘 | Rotondi M Magri F Chiovato L | 2010 | JA-MA2010，304，22： | 1 |
| 10 | Role of conventional ultrasonography and color flow-doppler sonography in predicting malignancy in 'cold' thyroid nodules显示文摘 | Rago T Vitti P Chiovato L | 1998 | Eur J Endocrinol1998，138，1： | 1 |
| 11 | Thyroid and lipid metabolism显示文摘 | Pucci E Chiovato L Pinchera A | 2000 | IntJ Obes Relat Metab Disord2000，24，2： | 1 |
| 12 | Thyroid uhrasonography as a tool for detecting thyroid autoimmune diseases and predicting thyroid dysfunction in apparently healthy subjects显示文摘 | Rago T Chiovato L Grasso L | 2001 | J Endoerinol Invest2001，24，10： | 1 |
| 13 | Role of chemokines in endocrine autoimmune diseases 显示文摘 | Rotondi M Chiovato L Romagnani S | 2007 | Endocr Rev2007，28，5： | 1 |
| 14 | Outcome of Thyroid Function in Groves' Patients Treated with Radioiodine:Role of Thyroid-Stimulating and Thyrotropin-Blocking Antibodies and of Radioiodine-Induced Thyroid Damage显示文摘 | Chiovato L Fiore E Vitti P | 1998 | J Clin Endocrinol Metab1998，83，1： | 1 |
| 15 | Risk of coronary heart disease and mortality for adults with subclinical 显示文摘 | Rotondi M Magri F Chiovato L | 2010 | JAMA2010，304，22： | 1 |
| 16 | Role of conventional ultrasonography and color flow-doppler sonography in predicting malignancy in cold thyroid nodules显示文摘 | Rago T Vitti P Chiovato L | | 0，，01： | 1 |
| 17 | Outcome of thyroid function in Graves′patients treated with radioidine; role of thyroid-stimulating and thyrotropin-hlocking antibodies and of radioidine dose in patients with Graves′disease, a clinical outcome study 显示文摘 | Chiovato L Fiore E Vitti P | 2001 | Eur J Nucl Med2001，28，10： | 1 |
| 18 | Role of conventional ultrasonography and color flow Doppler sonography in predicting malignant in 'cold' thyroid nodules显示文摘 | Rago T Vitti P Chiovato L | 1995 | J Clin Ultrasound1995，23，2： | 1 |
| 19 | Orbital cobalt irradiation combined with systemic corticosteroids for Graves' ophthalmopathy: comparison with systemic corticosteroids alone 显示文摘 | Bartalena L Marcocci C Chiovato L | 1983 | J Clin Endocrinol Metab1983，56，6： | 1 |
| 20 | The expression of the mi-crosomal/peroxidase autoantigen in human thyroid cells isthyrotrophin-dependent显示文摘 | Chiovato L Vitti P Cucchi P | 1989 | Clin Exp Immunol1989，76，1： | 1 |
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