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| 1 | Clinical and Laboratory Findings of Nonacute Neurobrucellosis显示文摘INTRODUCTION Brucellosis is the most common zoonotic infection in the world.It is an endemic disease in many areas throughout the world.Human brucellosis is a multisystem disease that may present with a broad spectrum of clinical manifestations.The central nervous system (CNS) involvement is a rare but serious neurological complication of brucellosis.Neurobrucellosis (NB) often is underdiagnosed,which is partly because of unawareness about the disease among the treating physicians.Clinically nonacute NB is more common than acute NB.Therefore,in order to better understand the nonacute NB,we summarized 14 cases,aimed to shed light to detailed neurologic features of nonacute NB,as well as their laboratory findings. | Li-Dong Jiao Chang-Biao Chu Chhetri Jagadish Kumar Jie Cui Xian-Ling Wang Li-Yong Wu Cun-Jiang Li Xiang-Bo Wang | 2015 | Chinese Medical Journal2015，，13： | 24 |
| 2 | Seroepidemiology of Helicobacter pylori infection in elderly people in the Beijing region, China显示文摘AIM:To investigate seroepidemiology of cagA+and vacA+strains of Helicobacter pylori(H.pylori)in an elderly population in Beijing and to determine risk factors for seropositivity.METHODS:A total of 2006 elderly persons(>60years)were selected using a random cluster sampling method in different parts of the Beijing area(urban,suburban and mountainous districts).Structured questionnaires were completed during home visits,including history of H.pylori infection,history of gastrointestinal diseases,diet types,hygiene habits,occupation and economic status.Blood samples(2 mL)were collected from each participant,and serum IgG antibodies to cagA,vacA and H.pylori urease antigens were measured by immunodetection.RESULTS:The prevalence of H.pylori infection in elderly subjects was 83.4%and the typeⅠH.pylori strain infection rate was 56%.The seroprevalence for typeⅠH.pylori strain infection in urban and suburbandistricts was higher than that in the mountainous areas(P<0.001).Elderly subjects who had previously performed manual labor or were in the young-old age group(age<75 years)had a higher seroprevalence of H.pylori infection than those who had previously performed mental labor or were in the oldest-old age group(age≥75 year)(P<0.05).The typeⅠH.pylori strain infection rate in the elderly with vegetarian diets was higher than in those eating high-protein foods(P<0.001).There was no significant difference in the prevalence of H.pylori strains between male and female elderly participants(P>0.05).CONCLUSION:TypeⅠH.pylori seroprevalence is higher in elderly people.The distribution of strains of H.pylori is significantly affected by age,area and dietary habits. | Mei Zhang Ying-Zhi Zhou Xiao-Ying Li Zhe Tang Hong-Ming Zhu Yan Yang Jagadish K Chhetri | 2014 | World Journal of Gastroenterology2014，20，13： | 17 |
| 3 | Contemporary and Historic Population Structure of Abies spectabilis at Treeline in Barun Valley,Eastern Nepal Himalaya显示文摘Treeline ecotone dynamics of Abies spectabilis(D. Don) Mirb. in the Barun valley,Makalu Barun National Park, eastern Nepal Himalaya were studied by establishing seven plots(20 m ×variable length) from the forestline to the tree species limit: three plots on the south- and north-facing slopes each(S1-S3, N1-N3), and one plot on the eastfacing slope(E) in the relatively undisturbed forests.A dendroecological method was used to study treeline advance rate and recruitment pattern. In all the plots,most trees established in the early 20 th century, and establishment in the second half of the 20 th century was confined to the forestline area. Treeline position has not advanced substantially in the Barun valley,with only 22 m average elevational shift in the last 130 years, and with average current shifting rate of 14cm/yr. Moreover, no significant relationship was found between tree age and elevation on the south-,north-, and east-facing slopes. The number of seedlings and saplings in near the treeline area was negligible compared to that near the forestline area.Therefore, A. spectabilis treeline response to the temperature change was slow, despite the increasing temperature trend in the region. Beside the temperature change, factors such as high inter-annual variability in temperature, dense shrub cover, and local topography also play an important role in treeline advance and controlling recruitment pattern above the treeline. | Parveen Kumar CHHETRI David M.CAIRNS | 2015 | Journal of Mountain Science2015，12，3： | 10 |
| 4 | A laser ablated graphene-based flexible self-powered pressure sensor for human gestures and finger pulse monitoring显示文摘Flexible triboelectric nanogenerators (TENGs)-based pressure sensors are very essential for the wide-range applications, comprising wearable healthcare systems, intuitive human-device interfaces, electronic-skin (e-skin), and artificial intelligence. Most of conventional fabrication methods used to produce high-performance TENGs involve plasma treatment, photolithography, printing, and electro-deposition. However, these fabrication techniques are expensive, multi-step, time-consuming and not suitable for mass production, which are the main barriers for efficient and cost-effective commercialization of TENGs. Here, we established a highly reliable scheme for the fabrication of a novel eco-friendly, low cost, and TENG-based pressure sensor (TEPS) designed for usage in self-powered-human gesture detection (SP-HGD) likewise wearable healthcare applications. The sensors with microstructured electrodes performed well with high sensitivity (7.697 kPa^-1), a lower limit of detection (~ 1 Pa), faster response time (< 9.9 ms), and highly stable over > 4,000 compression-releasing cycles. The proposed method is suitable for the adaptable fabrication of TEPS at an extremely low cost with possible applications in self-powered systems, especially e-skin and healthcare applications. | Partha Sarati Das Ashok Chhetry Pukar Maharjan M. Salauddin Rasel Jae Yeong Park | 2019 | Nano Research2019，12，8： | 8 |
| 5 | Prognostic analysis and comparison of colon cancer in Han and Hui patients显示文摘AIM:To investigate the relevant prognostic factors and their differences between colorectal cancer(CRC)patients of Chinese Han and Hui ethnicities in the Beijing region.METHODS:A retrospective analysis of 880 patients diagnosed with CRC at Xuanwu Hospital,Capital Medical University between September 2001 and September2011 was performed.Among the 880 patients,398 and482 were Hui and Han,respectively.Characteristics including sex,age,diet,tumor size,primary tumor site,Dukes’stage and degree of differentiation were analyzed for their influence on prognosis.Data on dietary structures were recorded through a questionnaire survey conducted during the patient’s first visit,return visit or follow-up checkups.RESULTS:Among patients with colon cancer,the5-year survival rate for patients of Hui ethnicity was lower than that for Han patients(P=0.025).Six risk factors(age of onset,dietary structure,tumor size,Dukes’stage,location of cancer and degree of differentiation)in both Han and Hui patients were identified as prognostic factors(P<0.05).Multivariate analysis showed that age of onset(P=0.002),diet(P=0.000),Dukes’stage(P=0.000)and degree of differentiation(P=0.000)are prognostic factors affecting both ethnic groups.Comparison of prognostic factors between Han and Hui patients with CRC showed that dietary structure was a statistically significant factor,and diet varied significantly between the two ethnic groups.CONCLUSION:Dietary structure has a significant influence on colon cancer prognosis among Han and Hui patients with colon cancer in Beijing,which may cause a difference in their survival rates. | Mei Zhang Qu-Chuan Zhao Yan-Peng Liu Lei Yang Hong-Ming Zhu Jagadish K Chhetri | 2014 | World Journal of Gastroenterology2014，20，17： | 6 |
| 6 | Dendroclimatic response of Abies spectabilis at treeline ecotone of Barun Valley, eastern Nepal Himalaya显示文摘A dendroclimatic study was conducted in the treeline ecotone of Barun Valley,eastern Nepal,to determine the tree-ring climate response and ring width trend of Abies spectabilis.A 160-year-old chronology,from 1850 to 2010,was developed from 38 tree-ring samples.No higher growth in recent decades was observed in tree-ring width in this area.The mean temperature of the current year in February and in the combined winter months of December,January,and February showed significant positive correlation with tree-ring width,although no significant correlation was found between tree-ring width and the precipitation pattern of the region.This tree-ring climate response result is different from that in other studies in Nepal,which could be attributed to location and elevation. | Parveen Kumar Chhetri David M.Cairns | 2016 | Journal of Forestry Research2016，27，5： | 4 |
| 7 | Amount and temperature effects responsible for precipitation isotope variation in the southern slope of Himalayas显示文摘Seasonal variation of stable isotopes in precipitation of Kathmandu Valley on the southern slope of Himalaya was carried out to understand the controlling mechanism of amount and temperature effect on the basis of one year stable isotope data from 2010 to 2011. Highly depleted isotope values in major rainy period are obtained just after the onset of precipitation in summer, which accounts for 'amount effect' due to saturation isotopic compositions in high moisture condition, whereas, the higher values in winter are indicative to regional vapors (temperature effect) recycling of various sources. An abrupt depletion of isotope values in mid-June, indicates the onset date of monsoon precipitation, by the replacement of winter air mass with southern monsoon. Thus, precipitation isotopes are a tool revealing the onset date of summer monsoon and temporal features of variability, in local and regional monsoons precipitations. A comparison of long term monthly values of δ 18 O, temperature, and precipitation with GNIP δ 18 O data shows the temporal variations of stable isotopes are mostly controlled by amount and temperature effects. During summer monsoon, the amount effects are stronger for high values of precipitation (R=0.7) and altitude effect appears for low moisture in late rainy season, thus from December to June (winter to pre-monsoon) the controlling features of isotopes remains under the temperature effect. A temporal rate of temperature effect is derived as 0.04‰ per year which indicates a dry signal of atmospheric condition and a temperature relation δ 18 O=(0.371±0.08)T+(0.156±0.05) is obtained from this analysis. The meteoric water lines of Kathmandu before and after monsoon onset of 2011, are found as δD=(4.36±0.3)δ 18 O+(15.66±1.2) and δD=(6.91±0.2)δ 18 O (7.92±2.26) from lab samples result, and δD=9.2δ 18 O+11.725 and δD=8.53δ 18 O+16.65 from GNIP data, which lacks the consistency both for slopes and intercepts values for the study period. The mean lapse rate values of δ 18 O and δD from GNIP data are obtained as 0.002‰/m and 0.015 ‰/m, which indicate the altitudinal effects in regional precipitation of the southern slope of Himalayas. This study estimates new stable isotopes data in recent precipitation using simple methodology which can be important for regional precipitation monitoring systems, environmental change and paleo-climatic studies. | Tek Bahadur Chhetri TanDong Yao LiDe Tian XinPing Zhang | 2013 | Research in Cold and Arid Regions2013，5，2： | 3 |
| 8 | 经皮微创锁定钢板内固定治疗胫骨中下段骨折98例显示文摘目的:探讨经皮微创锁定钢板内固定治疗胫骨中下段闭合性骨折的临床疗效。方法:使用锁定钢板经皮微创技术对闭合性胫骨中下段骨折98例进行闭合复位内固定治疗,术后随访,进行疗效观察与分析。结果:术后平均随访13.2月,除失访1例外,骨折均愈合良好97例,功能恢复正常。结论:锁定钢板经皮微创技术是治疗胫骨骨折的新型生物学微创治疗方法,能够减少手术时间,创伤较小,术中出血少,术后患者康复较快,并发症少,提高了患者治愈率,具有良好的临床效果和进一步推广价值。 | Sumit Chhetri 李五洲 储伟 刘克斌 | 2015 | 长江大学学报(自科版)(下旬)2015，12，4： | 3 |
| 9 | Modeling Spatial–Temporal Dynamics of Urban Residential Fire Risk Using a Markov Chain Technique显示文摘This article applies a Markov chain method to compute the probability of residential fire occurrence based on past fire history. Fitted with the fire incidence data gathered over a period of 10 years in Melbourne, Australia,the spatially-integrated fire risk model predicts the likely occurrence of fire incidents using space and time as key model parameters. The mapped probabilities of fire occurrence across Melbourne show a city-centric spatial pattern where inner-city areas are relatively more vulnerable to a fire than outer suburbia. Fire risk reduces in a neighborhood when there is at least one fire in the last1 month. The results show that the time threshold of reduced fire risk after the fire occurrence is about 2 months.Fire risk increases when there is no fire in the last 1 month within the third-order neighborhood(within 5 km). A fire that occurs within this distance range, however, has no significant effect on reducing fire risk level within the neighborhood. The spatial–temporal dependencies of fire risk provide new empirical evidence useful for fire agencies to effectively plan and implement geo-targeted fire risk interventions and education programs to mitigate potential fire risk in areas where and when they are most needed. | Rifan Ardianto Prem Chhetri | 2019 | International Journal of Disaster Risk Science2019，10，1： | 2 |
| 10 | CUMS and dexamethasone induce depression- like phenotypes in mice by differentially altering gut microbiota and triggering macroglia activation显示文摘Background Although the link between gut microbiota and depression has been suggested,changes of gut microbiota vary largely among individuals with depression.Aims Explore the heterogeneity of microbiota-gut-brain axis and new pathogenic characteristics in murine models of depression.Methods Adolescent female mice were randomly divided into control(CON)group(n=10),chronic unexpected mild stress(CUMS)group(n=15)and dexamethasone(DEX)group(n=15).Mice in the DEX group were gavaged twice a day with 0.2 mg/kg of DEX for 5 weeks,whereas CON mice were given the same amount of solvent.Mice in the CUMS group were exposed to stressors.After behavioural evaluations,all mice were sacrificed for harvesting tissues and blood samples.Enzyme-linked immunosorbent assay(ELISA)was conducted for measuring levels of corticosterone(CORT)and interleukin-1β(IL-1β)in sera,whereas levels of protein expression in colon and hippocampal tissues were examined by western blot.Faecal microbial communities were analysed by sequencing 16S rDNAs.Results Mice in CUMS and DEX groups exhibited severe depression-like behaviours.Compared with CON mice,CUMS-exposed mice showed a significant increase in bothαandβdiversity.Prevotellaceae and Desulfovibrio were enriched,whereas Bacilli were decreased in the faeces of mice in the CUMS group.DEX-treated mice had a decrease in the abundance of Clostridium XVIII.Levels of occludin in colon tissue of DEX-treated mice were reduced.Relative to mice in the CON and CUMS groups,DEX-treated mice contained higher serum levels of CORT and IL-1β.Compared with CON mice,mice in the DEX and CUMS groups had higher levels of IL-1βin sera and lower levels of glial fibrillary acidic protein(GFAP),Nestin,Synapsin-1 and P2Y12 receptor in the hippocampus.Conclusions Changes of gut microbiota diversity,intestinal integrity and neuroinflammation in the brain contribute to CUMS-induced depression,whereas pathobionts and excessive immunosuppression with damaged neuronal synapses is a basis of the DEX-induced depression. | Jing Wu Jinhang Li Chhetri Gaurav Usman Muhammad Yantian Chen Xueyi Li Jinghong Chen Zejian Wang | 2021 | General Psychiatry2021，34，6： | 2 |
| 11 | Combined fracture dislocation of the navicular bone along with cuboid, cuneiform and longitudinal split fracture of the lateral malleolus: a rare combination of fractures显示文摘船形的骨头,长方体的破裂,楔形文字,和侧面的踝的纵的裂口骨折的破裂脱臼是破裂的稀罕联合。这是高速度损害破裂并且能被脚的强迫的脚底的屈曲和倒置在影响的时候引起到地面上。这里,我们在被开的减小和固定为侧面的踝与三分之一个管状的盘子为船形的骨头,和二个 interfragmentary 螺丝钉与一个部分线程的螺丝钉和二 K 电线对待的一个 35 岁的男病人报导了如此的一个案例。K 电线被移开 6 在外科以后的星期由部分重量适用列在后面。在 6 以后;月,病人能最小的疼痛地通常走并且脚胀大。 | Kapil Mani Khatri Chhetri Parimal Acharya Dirgha Raj Rokaya Chhetri | 2014 | Chinese Journal of Traumatology2014，17，6： | 2 |
| 12 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 13 | Lamina propria replacement therapy with cultured autologous fibroblasts for vocal fold scars显示文摘 | CHHETRI D K HEAD C REVAZOVA E | 2004 | Otolaryngol Head Neck Surg2004，131，： | 1 |
| 14 | Estimating the weight of children in Nepal by Broselow, PAWPER XL and Mercy method显示文摘BACKGROUND: Resuscitation of a critically-ill child requires an accurate weight for fluids and medication dosing; however, weighing children on a scale while critically ill is not always practical. The objective of this study is to determine the accuracy of three different weight estimation methods(Broselow, PAWPER XL and Mercy tape) of children presenting to Patan Hospital, Nepal.METHODS: This was a prospective, cross-sectional study that included children presenting to the emergency department and under-fourteen outpatient clinic at Patan Hospital. Measured weight was compared to estimated weight of Broselow, PAWPER XL, and Mercy tapes. The mean percentage error and percentage of estimated weights that were within 10%(PW10) and 20%(PW20) of actual weight were calculated. Acceptable accuracy was determined as a PW10>70% and PW20>95%. A Bland-Altman analysis was done to determine agreement between each weight estimation method and actual weight.RESULTS: The study included 813 children. The mean age was 4.2 years(ranging from 4 days to 14 years) with 60% male. The mean percentage error(MPE) for Broselow, PAWPER XL and Mercy were –1.0%(SD 11.8), 0.7%(10.5) and 4.2%(11.9) respectively. The predicted weight within 10% was highest for the PAWPER XL(71.5%) followed by Broselow(63.2%) and Mercy(58.1%). The predicted weight within 20% of actual weight was 95.2%, 91.5% and 91.3% for PAWPER XL, Broselow and Mercy respectively.CONCLUSION: The PAWPER XL tape was the only method found to be accurate in estimating the weight of Nepalese children. | Karun Shrestha Prakriti Subedi Oshna Pandey Likhita Shakya Kailash Chhetri Darlene R.House | 2018 | World Journal of Emergency Medicine2018，9，4： | 1 |
| 15 | Environmental resources reduce income inequality and the prevalence:depth and severity of poverty in rural Nepal显示文摘 | CHHETRI B B K LARSEN H O SMITH-HALL C | 2015 | Environment Development and Sustainability2015，17，51： | 1 |
| 16 | Combined arytenoid adduction and laryngeal reinnervation in the treatment of vocal void paralysis显示文摘 | Chhetri DK Gerratt BR Kreiman J | 1999 | Laryngoscope1999，109，： | 1 |
| 17 | Carcinoma of the buccal mucosa 显示文摘 | Chhetri DK Rawnsley JD Calcaterra TC | 2000 | Otolaryngol Head Neck Surg2000，123，5： | 1 |
| 18 | Human fetal adrenal transplant :a possible role in relieving intractable pain in advanced rheumatoid arthritis显示文摘 | Bhattacharya N Chhetri MK Mukherjee KL | 2002 | Clin Exp Obstet Gynecol2002，29，3： | 1 |
| 19 | L-myo-inositol-l-phos- phate synthase expressed in developing organ: isolation and character- isation of the enzyme from human fetal liver显示文摘 | Chhetri DR Gupta S Mukherjee AK | 2012 | Appl Biochem Bio- techno12012，167，8： | 1 |
| 20 | Long- term follow up results of selective laryngeal adductor denervation reinnervation surgery for adductor spasmodic dysphonia 显示文摘 | Chhetri DK Mendelsohn AH Blumin JH | | Laryngoscope0，116，： | 1 |
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