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| 1 | Non-invasive versus invasive mechanical ventilation for respiratory failure in severe acute respiratory syndrome显示文摘Background Severe acute respiratory syndrome is frequently complicated by respiratory failure requiringventilatory support.We aimed to compare the efficacy of non-invasive ventilation against invasive mechanicalventilation treating respiratory failure in this disease.Methods Retrospective analysis was conducted on all respiratory failure patients identified from the HongKong Hospital Authority Severe Acute Respiratory Syndrome Database.Intubation rate, mortality and secondaryoutcome of a hospital utilizing non-invasive ventilation under standard infection control conditions ( NIVHospital) were compared against13 hospitals using solely invasive ventilation (IMVHospitals).Multiple logisticregression analyses with adjustments for confounding variables were performed to test for association betweenoutcomes and hospital groups.Results Both hospital groups had comparable demographics and clinical profiles, but NIV Hospital (42patients) had higher lactate dehydrogenase ratio and worse radiographic score on admission and ribavirin-corticosteroid commencement.Compared to IMV Hospitals (451 patients), NIV Hospital had lower adjustedodds ratios for intubation (0.36, 95% CI 0.164 -0.791,P=0.011) and death (0.235, 95% CI 0.077 -0.716,P=0.011), and improved earlier after pulsed steroid rescue.There were no instances of transmission ofsevere acute respiratory syndrome among health care workers due to the use of non-invasive ventilation.Conclusion Compared to invasive mechanical ventilation, non-invasive ventilation as initial ventilatory supportfor acute respiratory failure in the presence of severe acute respiratory syndrome appeared to be associated withreduced intubation need and mortality. | Loretta YC Yam Alfred YF Chan Thomas MT Cheung Eva LH Tsui Jane CK Chan Vivian CW Wong | 2005 | Chinese Medical Journal2005，，17： | 3 |
| 2 | Airway obstruction in children with congenital heart disease: assessment by flexible bronchoseopy显示文摘 | Lee SL Cheung YF Leung MP | 2002 | Pediatr Pulmonol2002，34，4： | 1 |
| 3 | Usefulness of laser-assisted valvotomy with balloon valvoplasty for pulmonary valve atresia with intact ventricular septum显示文摘 | Leung MP Chau AK | 2002 | Am J Cardiol2002，90，4： | 1 |
| 4 | Protein profiling of cervical cancer byprotein-biochips: proteomic scoring to discriminate cervical cancer from normal cervix 显示文摘 | Wong YF Cheung T H Lo KW | 2004 | Cancer Lett2004，211，： | 1 |
| 5 | Novel area strain based on three-dimensional wall motion analysis for assessment of global left ventricular performance after repair of tetralogy of fallot显示文摘 | Li SN Wong SJ Cheung YF | | 0，，： | 1 |
| 6 | Modulating effects of mannose-binding lectin genotype on arterial stiffness in children after Kawasaki disease显示文摘 | Cheung YF Ho MH Ip WK | 2004 | Pediatr Res2004，56，4： | 1 |
| 7 | Traeheobronehography and angiocardiography of paediatric cardiac patients with airway disorders显示文摘 | Cheung YF Lee SL Leung MP | 2002 | J Paediatr Child Health2002，38，： | 1 |
| 8 | Inflammatory gene polymorphisms and susceptibility to Kawasaki disease and arterial sequelae显示文摘 | Cheung YF Huang GY Chen SB | 2008 | Pediatrics2008，122，3： | 1 |
| 9 | The possible role of hydrogen sulfide as a smooth musele cell proliferation in- hibitor in rat cultured cells 显示文摘 | Du JB Yah H Cheung YF | 2004 | Heart Vessels2004，19，2： | 1 |
| 10 | Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonncleotide microarray 显示文摘 | Wong YF Cheung TH Tsao GS | 2006 | Int J Cancer2006，118，10： | 1 |
| 11 | Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray显示文摘 | Wong YF Cheung TH Tsao GS | 2006 | Int J Cancer2006，118，10： | 1 |
| 12 | Airway obstruction in children with congenital heart disease: assessment by flexible bronehoscopy 显示文摘 | Lee SL Cheung YF Leung MP eta! | 2002 | Pediatr Pulmonol2002，34，4： | 1 |
| 13 | PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6(PDE4D6)显示文摘 | Cheung YF Kan Z Garrett-Engele P | 2007 | J Pharmacol Exp Ther2007，322，2： | 1 |
| 14 | Sonographic differentiation of invasive and intraductal carcinomas of the breast显示文摘 | Chen SC Cheung YC Lo YF | 2003 | Br J Radiol2003，76，909： | 1 |
| 15 | Genome-wide gene expression profiling of cervical cancer in Hang Kong women by oligonucleotide microarray 显示文摘 | Wang YF Cheung TH Tsao GS | 2006 | Int J Cancer2006，118，： | 1 |
| 16 | Genone-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray显示文摘 | Wong YF Cheung TH | 2006 | Int J Cancer2006，118，10： | 1 |
| 17 | Genome -wide gene expression profding of cervical cancer in Hong Kong women by oligonucleotide microarray 显示文摘 | Wong YF Cheung TH | 2006 | Int J Cancer2006，118，10： | 1 |
| 18 | p16INK4A and p1SI NK4B alterations in primary gyneclogic malignancy 显示文摘 | WONG YF CHUNG TK CHEUNG TH | 1997 | Gynecol Onool1997，65，： | 1 |
| 19 | Frequent loss of heterozygosity of chromosome 3 short arm detected by PCR-based microsatellite polymorphisms in cervical squamous cell carcinoma显示文摘 | Wong YF Chung TK Cheung TH | | 0，，： | 1 |
| 20 | Novel and traditional cardiovascular risk factors in children after Kawasaki disease:implications for premature atherosclerosis显示文摘 | Cheung YF Yung TC Tam SC | | 0，，01： | 1 |
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