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| 1 | 澳大利亚临床共识指南:儿童卒中的诊断和急性期处理显示文摘卒中是导致儿童死亡的十大原因之一,幸存的致残患儿将面临几十年的残疾生活,给患儿及其家庭带来了巨大负担。由于安全性和有效性的证据有限,以及诊断的延误,目前卒中患儿无法接受再灌注治疗。儿童卒中诊断和急性期处理的澳大利亚临床共识指南,旨在最大限度地减少临床诊疗中的不确定性,并记录与成人卒中不同的危险因素、病因和假性卒中情况的最佳证据。临床问题的阐述来自于对2007年至2017年数据库的系统检索,但仅限于英语和儿科研究。该指南应用SIGN方法和国家健康与医学研究委员会系统对证据进行筛选和分类,通过推荐、评估、发展和评价系统(GRADE系统)对推荐进行强弱分级。该指南提供了60多项基于证据的推荐,以帮助参与院前和急症处理的临床医师快速识别儿童卒中,选择最合适的初步检查方案来确定诊断、明确病因,并选择最恰当的干预措施以挽救脑组织、预防复发。同时,指南也提供了颅内压和先天性心脏病管理方面的推荐。该指南的实施需要将院前和急诊系统重组,包括建立区域性卒中网络,建立儿科卒中疾病编码,快速MRI,以及对能够提供再灌注治疗的初级儿科卒中中心进行认证。该指南能够审核治疗的基准时间线,获得急性期的干预措施及预后判断。它还将促进澳大利亚儿童卒中登记的发展,并与国际登记处建立数据联系,以便准确收集卒中发病率、治疗和结果相关的数据。 | Medley TL Miteff C Andrews I Ware T Cheung M Monagle P Mandelstam S Wray A Pridmore C Troedson C Dale RC Fahey M Sinclair A Walsh P Stojanovski S Macka MT 徐佳丽(译) 吴川杰(译) 肖潇(译) 吕俊萱(译) 张博维(译) 吉训明(译) | 2019 | 中国脑血管病杂志2019，16，4： | 9 |
| 2 | Non-invasive versus invasive mechanical ventilation for respiratory failure in severe acute respiratory syndrome显示文摘Background Severe acute respiratory syndrome is frequently complicated by respiratory failure requiringventilatory support.We aimed to compare the efficacy of non-invasive ventilation against invasive mechanicalventilation treating respiratory failure in this disease.Methods Retrospective analysis was conducted on all respiratory failure patients identified from the HongKong Hospital Authority Severe Acute Respiratory Syndrome Database.Intubation rate, mortality and secondaryoutcome of a hospital utilizing non-invasive ventilation under standard infection control conditions ( NIVHospital) were compared against13 hospitals using solely invasive ventilation (IMVHospitals).Multiple logisticregression analyses with adjustments for confounding variables were performed to test for association betweenoutcomes and hospital groups.Results Both hospital groups had comparable demographics and clinical profiles, but NIV Hospital (42patients) had higher lactate dehydrogenase ratio and worse radiographic score on admission and ribavirin-corticosteroid commencement.Compared to IMV Hospitals (451 patients), NIV Hospital had lower adjustedodds ratios for intubation (0.36, 95% CI 0.164 -0.791,P=0.011) and death (0.235, 95% CI 0.077 -0.716,P=0.011), and improved earlier after pulsed steroid rescue.There were no instances of transmission ofsevere acute respiratory syndrome among health care workers due to the use of non-invasive ventilation.Conclusion Compared to invasive mechanical ventilation, non-invasive ventilation as initial ventilatory supportfor acute respiratory failure in the presence of severe acute respiratory syndrome appeared to be associated withreduced intubation need and mortality. | Loretta YC Yam Alfred YF Chan Thomas MT Cheung Eva LH Tsui Jane CK Chan Vivian CW Wong | 2005 | Chinese Medical Journal2005，，17： | 3 |
| 3 | Surgical treatment of parastomal hernia complicating sigmoid colostomies显示文摘 | Cheung MT Chia NH Chiu WY | 2001 | Dis Colon Rectum2001，44，2： | 1 |
| 4 | Live resection for intrahepatic stones 显示文摘 | Cheung MT Kwoc PC | 2005 | Arch Sung2005，140，10： | 1 |
| 5 | Surgical treatment of parastomal hernia complicating sigmoid colostomies 显示文摘 | Cheung MT Chia NH Chiu WY | 2001 | Dis Colon Rectum2001，44，2： | 1 |
| 6 | Postoperative choledochoscopic removal of intrahepat-ic stones via a T tube tract 显示文摘 | Cheung MT | 1997 | Br J Sui^1997，84，9： | 1 |
| 7 | Surgical treatment of parastomal hernia complicating sigmoid colostomies 显示文摘 | Cheung MT Chia NH Chiu WY | 2001 | Dis Colon Rec- tum2001，44，2： | 1 |
| 8 | Mitotic arrest deficient 2 expression induces ehemosensitization to a DNA damaging agent, cisplatin, in nasopharyngeal carcinoma cells 显示文摘 | Cheung HW Jin DY Ling MT | 2005 | Cancer Res2005，65，8： | 1 |
| 9 | Postoperative choledochoscopic removal of intrahepat- ic stones via a t tube tract显示文摘 | Cheung MT | 1997 | Br J Surg1997，84，9： | 1 |
| 10 | Efficacy of Noninvasive positive pressure ventilation to treats severe acute respiratory and acute respiratory failure显示文摘 | Thomas MT Cheung Lorette YC yam | 2004 | Chest2004，126，： | 1 |
| 11 | Surgical treatment of parastomal hernia complicating sigmoid colostomies 显示文摘 | Cheung MT Chia NH Chia WY | 2001 | Dis Colon Rectum2001，44，2： | 1 |
| 12 | Liver resection for intraheoatic stones 显示文摘 | Cheung MT Kwok PC | 2005 | Arch Surg2005，140，10： | 1 |
| 13 | Surgical treatment of parastomal hernia complicating sigmoid colostomies显示文摘 | Cheung MT Chia NH Chiu WY | 2001 | Dis Colon Rectum2001，44，2： | 1 |
| 14 | Quantification of plasma beta - catenin mRNA in colorectal cancer and adenoma patients显示文摘 | Wong SC Lo SF Cheung MT | 2004 | Clin Cancer Res2004，10，5： | 1 |
| 15 | Kainate induced apoptosis in cultured murine cerebellar granule cells elevates expression of the cell cycle gene CyclinDl 显示文摘 | Cheung NS Reid MT | 1998 | J Neurochem1998，71，： | 1 |
| 16 | Id-1-induced Raf/MEK pathway activation is essential for its protective role a-gainst taxol-induced apoptosis in nasopharyngeal carcinoma cells显示文摘 | Cheung HW Ling MT Tsao SW | 2004 | Carcinogenesis2004，25，6： | 1 |
| 17 | Use of non - invasive positive- pressure ventilation for acute respiratory failure: prospective study 显示文摘 | Cheung MT Yarn LY Lau CW Ching CK Lee CH | 2000 | Hog Kong Med J2000，6，4： | 1 |
| 18 | Liver resection for intrahepatic stones 显示文摘 | Cheung MT Kwok PC | 2005 | Arch Surg2005，140，10： | 1 |
| 19 | Id-1-induced Raf/MEK pathway activation is essential for its protective role against taxol-induced apoptos-is in nasopharyngeal carcinoma cells 显示文摘 | Cheung HW Ling MT Tsao SW | 2004 | Carcinogenesis2004，25，： | 1 |
| 20 | Percutaneous drainage and necrosectomy in the management of pancreatic necrosis显示文摘 | Cheung MT Ho CN Siu KW | 2005 | Anz J Surg2005，75，4： | 1 |
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