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| 1 | Cyclin A2:At the crossroads of cell cycle and cell invasion显示文摘Cyclin A2 is an essential regulator of the cell division cycle through the activation of kinases that participate to the regulation of S phase as well as the mitotic entry. However,whereas its degradation by the proteasome in mid mitosis was thought to be essential for mitosis to proceed,recent observations show that a small fraction of cyclin A2 persists beyond metaphase and is degraded by autophagy. Its implication in the control of cytoskeletal dynamics and cell movement has unveiled its role in the modulation of Rho A activity. Since this GTPase is involved in both cell rounding early in mitosis and later,in the formation of the cleavage furrow,this suggests that cyclin A2 is a novel actor in cytokinesis. Taken together,these data point to this cyclin as a potential mediator of cell-niche interactions whose dysregulation could be taken as a hallmark of metastasis. | Abdelhalim Loukil Caroline T Cheung Nawal Bendris Bénédicte Lemmers Marion Peter Jean Marie Blanchard | 2015 | World Journal of Biological Chemistry2015，6，4： | 6 |
| 2 | Two-photon excitation of the lowest 4f 2→4f 5d near-ultraviolet transitions in Pr3+ : Y3Al5O12 显示文摘 | Gayen S K Xie B Q Cheung Y M | 1992 | Phys Rev B1992，45，1： | 2 |
| 3 | Karaoke Theory in the Rehabilitation of mental patient显示文摘 | CM Leung Lee G Cheung B | 1998 | Singapore Medical Journal1998，4，： | 2 |
| 4 | The effect of talc on cell nucleation in extrusion foam processing of polypropylene with CO2 and isopentane显示文摘 | Park C B Cheung L K Song S W | 1998 | Cellular Polymers1998，17，4： | 2 |
| 5 | A recombinant human Fab expressed in Escherichia colt neutralizes rabies virus 显示文摘 | Cheung SC Dietzschold B Koprowski H | 1992 | JVirol1992，66，11： | 2 |
| 6 | Combination therapies improve the anticancer activities of retinoids in neuroblastoma显示文摘Most therapeutic protocols for child cancers use cytotoxic agents which have a narrow therapeutic index,and resulting in severe acute and chronic toxicities to normal tissues. Despite the fact that most child cancer patients achieve complete remission after chemotherapy,death still occurs due to relapse of persistent minimal residual disease(MRD) which remaining after initial cytotoxic chemotherapy. Advanced neuroblastoma(NB) is a leading cause of cancer deaths in young children. Retinoids are an important component of advanced NB therapy at the stage of MRD,yet half of all patients treated with 13-cis-retinoic acid still relapse and die. More effective combination therapies,with a lower side-effect profile,are required to improve outcomes for NB. Fenretinide or N-4-hydroxyphenyl retinamide is a synthetic derivative of retinoic acid which works on cancer cells through nuclear receptor-dependent and-independent signalling mechanisms. Moreover,several histone deacetylase inhibitors have entered early phase trials,and,suberoylanilide hydroxamic acid has been approved for use in adult cutaneous T cell lymphoma. A number of studies suggest that retinoid signal activation is necessary for histone deacetylase inhibitor activity. A better understanding of their mechanism of actions will lead to more evidence-based retinoid combination therapies. | Belamy B Cheung | 2015 | World Journal of Clinical Oncology2015，6，6： | 2 |
| 7 | Surface characterization in ultra-precision machining of Al/SiC metal matrix composites using data dependent systems analysis显示文摘 | CHEUNG C F CHAN K C LEE W B | 2003 | Journal of Materials Processing Technology2003，140，： | 1 |
| 8 | MDR1, the blood-brain barrier transporter, is associated with Parkinson's disease in ethnic Chinese 显示文摘 | LEE C G TANG K CHEUNG Y B | 2004 | J Med Genet2004，41，5： | 1 |
| 9 | Effect of Talc content on the cell- population density of extruded PP foams显示文摘 | C B Par L S Cheung | 1996 | Cellular and Microcellular Materials ASME1996，76，： | 1 |
| 10 | The possible roles of food derived bioaefive peptides in reducing the risk of cardiovascular disease显示文摘 | ERDMANN K CHEUNG B W Y SCHRODER H | 2008 | Journal of Nutritional Biochemistry2008，19，10： | 1 |
| 11 | Morphometric study of the apical anatomy of C-shaped root canal systems in mandibular second molars显示文摘 | Cheung GS Yang J Fan B | 2007 | Int Endod J2007，40，4： | 1 |
| 12 | Relation of arterial stiffness with gestational age and birth weight 显示文摘 | Cheung Y F Wong K Y Lam B C | 2004 | Arch Dis Child2004，89，3： | 1 |
| 13 | Protein profi- ting of microdissected prostate tissue links growth differ- entiation factor-15 to prostate carcinogenesis显示文摘 | Cheung PK Woolcock B Adomat H | 2004 | Cancer Res2004，64，32： | 1 |
| 14 | Hyperglycemia is associated with adverse outcomes in patients receiving total parenteral nutrition 显示文摘 | Cheung NW Napier B Zaccaria C | 2005 | Diabetes Care2005，28，10： | 1 |
| 15 | A systematic approach for knowledge audit analysis: integration of knowledge inv- entory, mapping and knowledge flow analysis显示文摘 | Choy S Y Lee W B Cheung C F | 2004 | Journal of Universal Computer Science2004，10，6： | 1 |
| 16 | Morphometric study of the apical anatomy of C-shaped root canal systems in mandibular second molars 显示文摘 | Cheung GS Yang J Fan B | 2007 | Int Endod J2007，40，4： | 1 |
| 17 | Composition of extracellular polymeric substances in the activated sludge floc matrix 显示文摘 | Bura R Cheung M Liao B | 1998 | Water Science and Technology1998，37，45： | 1 |
| 18 | Analysis of ret/PTC gene rearrangements refines the fine needle aspiration diagnosis of thyroid cancer 显示文摘 | Cheung CC Carydis B Ezzat S | 2001 | J Clin Endocrinol Metab2001，86，5： | 1 |
| 19 | Inflammatory gene polymorhisms and susceptibility to Kawasaki diseacs and arterial sequelae显示文摘 | Cheung Y F Huang G Y Chen S B | 2008 | Pediatrics2008，122，3： | 1 |
| 20 | Fabricalion and interfacial modification of woodrecycled plastic composite materlals显示文摘 | Cui Y H Lee S Noruziaan B Cheung M Tao J | 2008 | Composites: Part A2008，，39： | 1 |
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