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| 1 | Economic optimization for configuration and sizing of micro integrated energy systems显示文摘Based on analysis of construction and operation of micro integrated energy systems(MIES), this paper presents economic optimization for their configuration and sizing. After presenting typical models for MIES, a residential community MIES is developed by analyzing residential direct energy consumption within a general design procedure. Integrating with available current technologies and local resources, the systematic design considers a prime mover, fed by natural gas, with wind power, photovoltaic generation, and two storage devices serving thermal energy and power to satisfy cooling, heating and electricity demands. Control strategies for MIES also arepresented in this study. Multi-objective formulas are obtained by analyzing annual cost and dumped renewable energy to achieve optimal coordination of energy supply and demand. According to historical load data and the probability distribution of distributed generation output,clustering methods based on K-means and discretization methods are employed to obtain typical scenarios representative of uncertainties. The modified non-dominated sorting genetic algorithm is applied to find the Pareto frontier of the constructed multi-objective formulas. In addition, aiming to explore the Pareto frontier, the dumped energy cost ratio is defined to check the energy balance in different MIES designs and provide decision support for the investors. Finally, simulations and comparision show the appropriateness of the developed model and the applicability of the adopted optimization algorithm. | Haibo YU Chao ZHANG Zuqiang DENG Haifeng BIAN Chenjun SUN Chen JIA | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，2： | 10 |
| 2 | Pharmacological Activation of RXR-a Promotes Hematoma Absorption via a PPAR-y-dependent Pathway After Intracerebral Hemorrhage显示文摘Endogenously eliminating the hematoma is a favorable strategy in addressing intracerebral hemorrhage(ICH).This study sought to determine the role of retinoid X receptor-ot(RXR-a)in the context of hematoma absorption after ICH.Our results showed that pharmacologically activating RXR-a with bexarotene significantly accelerated hematoma clearance and alleviated neurological dysfunction after ICH.RXR-ot was expressed in microglia/macro-phages,neurons,and astrocytes.Mechanistically,bexarotene promoted the nuclear translocation of RXR-a and PPAR-y,as well as reducing neuroinflammation by modulating microglia/macrophage reprograming from the Ml into the M2 phenotype.Furthermore,all the beneficial effects of RXR-a in ICH were reversed by the PPAR-y inhibitor GW9662.In conclusion,the pharmacological activation of RXR-a confers robust neuroprotection against ICH by accelerating hematoma clearance and repolarizing microglia/macrophages towards the M2 phenotype through PPAR-y-related mechanisms.Our data support the notion that RXR-ot might be a promising therapeutic target for ICH. | Chaoran Xu Huaijun Chen Shengjun Zhou Chenjun Sun Xiaolong Xia Yucong Peng Jianfeng Zhuang Xiongjie Fu Hanhai Zeng Hang Zhou Yang Cao Qian Yu Yin Li Libin Hu Guoyang Zhou Feng Yan Gao Chen Jianru Li | 2021 | Neuroscience Bulletin2021，37，10： | 4 |
| 3 | DynamicMechanical and Chemorheology Analysis for the Blended Epoxy System with Polyurethane Modified Resin显示文摘As the important matrix material,epoxy resin has been widely used in the composites for various fields.On account of the poor toughness of epoxy resin limiting their suitability for advanced applications,considerable interests have been conducted to modify the epoxy resin to meet the engineering requirements.In this study,the bio-based polyurethane(PU)modified resin was adopted to modify the pure bisphenol-A epoxy by blending method with various proportions.Aiming to illuminate the curing behavior,mechanical and thermal properties,the blended epoxy systems were characterized by viscosity-time analysis,dynamic mechanical analysis(DMA)at different frequencies and temperatures,mechanical tensile test,thermogravimetric analysis(TGA)and Fourier transform infrared(FT-IR)spectroscopy.The results indicated that the introduction of PU modified epoxy was found to significantly inhibit the viscosity growth rates especially when the content of PU modified epoxy resin is higher than 60%.Notwithstanding the dynamic modulus and T_(g)reduced with the increment of PU modified epoxy,remarkable increment on the elongation at break was found and the flexibility was greatly promoted with the introduction of PU modified epoxy.The proportion of PU modified epoxy in the blends should be put balance considerations to obtain optimal mechanical properties.TGA results and FTIR spectrum demonstrated that the addition of PU modified epoxy did not change the thermal decomposition mechanism and chemical reaction mechanism,but the addition of PU modified epoxy inhibits the curing reaction of epoxy resin by measured and calculated the damping temperature domainT from 35.7℃ to 48.9℃. | Xue Xin Yu Rong Linping Su Zhengmei Qiu Chenjun Yang Ming Liang Ping Ji Guoqiang Zhong Zhanyong Yao | 2022 | Journal of Renewable Materials2022，10，4： | 2 |
| 4 | Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation显示文摘亲爱的编辑, | Hongmei Zhang Mei Li Yu Gao Chenjun Jia Xiaowei Pan Peng Cao Xuelin zhao Jiping Zhang Wenrui Chang | 2015 | Protein & Cell2015，6，2： | 1 |
| 5 | Control Design and Implementation of a Spiral Spring Energy Storage System Connected to a Grid via PMSG显示文摘For an innovative spiral spring energy storage system,the permanent magnet synchronous generator(PMSG)is utilized as the energy conversion device due to its simple structure,low weight and high torque.During power generation,the output torque and moment of inertia of the spiral spring are changing continuously and simultaneously and the parameters of the PMSG show uncertainties.Furthermore,the DC link voltage of the converter should be stable and the power injected into the grid needs to be controlled.First,the change features of the external power source and the uncertainties of the generator’s internal parameters are expressed as the comprehensive disturbances,which are introduced into the dynamic model of the PMSG and also modify the dynamic model.Then,the high gain observers are utilized to estimate the comprehensive disturbances,and an improved robust backstepping control scheme integrating L2 gain and high gain observers is proposed.Secondly,the gridside inverter controller for the DC voltage loop and reactive power loop is designed based on the backstepping theory.Finally,hardware implementation is fulfilled to verify the presented algorithm.The results show that high gain observers are able to accurately estimate the external and internal interferences;the proposed control scheme can effectively suppress the external and internal interferences and guarantees output current,operating speed of the PMSG and output reactive power to correctly track respective references,and effectively stabilize the DC link voltage. | Yang Yu Zengqiang Mi Xudong Guo Xitong Niu Xiaojiang Zheng Chenjun Sun | 2018 | CSEE Journal of Power and Energy Systems2018，4，3： | 1 |
| 6 | Genre Analysis and Comparison of Chinese and American Presidents' New Year Messages显示文摘各国政治领袖们的新年贺辞是每年一次的重要媒体事件。然而,作为一种特殊的政治话语,这类贺辞却是一个很少被应用语言学学者们研究的领域。本研究采用体裁研究方法(e.g., Halliday, 1978; 1985; Halliday & Hasan, 1989; Martin, 1984; Martin & Rose, 2003; Paltridge,2006)在社会文化语境、篇章结构和语言特点三个层面系统地分析了中美两国元首在 2007、2008 和 2009 三年所作的六篇新年贺辞。本研究表明,由于这些新年贺辞所共有的交际功能、相对固定的篇章结构和突出的词汇语法特点,它们可以被视为一种独立的体裁 (Bruce,2008)。本研究还发现,尽管两位国家元首的新年贺辞在以上三个层面都体现了各自的特点,但作为同一种特殊的政治话语它们都指向大批受众并以提升公共关系和争取政治支持为目的。本文还证明了体裁分析方法是揭示某一特殊话语的真实交际目的和呈现被综合使用的各种修辞与语言资源的强大工具,因而值得在其他话语研究中推广使用。 | DAI Chenjun FAN Yu | 2012 | Chinese Journal of Applied Linguistics2012，35，4： | 0 |
| 7 | X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl)phthalate-induced testis toxicity显示文摘As a widely used plasticizer,di-(2-ethylhexyl)phthalate(DEHP)is known to induce significant testicular injury.However,the potential mechanism and effects of pubertal exposure to DEHP on testis development remain unclear.In vivo,postnatal day(PND)21 male rats were gavaged with 0,250,and 500 mg/kg DEHP for ten days.Damage to the seminiferous epithelium and disturbed spermatogenesis were observed after DEHP exposure.Meanwhile,oxidative stress-induced injury and pyroptosis were activated.Both endoplasmic reticulum(ER)stress and mitophagy were involved in this process.Monoethylhexyl phthalate(MEHP)was used as the biometabolite of DEHP in vitro.The GC-1 and GC-2 cell lines were exposed to 0,100μM,200μM,and 400μM MEHP for 24 h.Reactive oxygen species(ROS)generation,oxidative stress damage,ER stress,mitophagy,and pyroptosis were significantly increased after MEHP exposure.The ultrastructure of the ER and mitochondria was destroyed.X-box binding protein 1(XBP1)was observed to be activated and translocated into the nucleus.ROS generation was inhibited by acetylcysteine.The levels of antioxidative stress,ER stress,mitophagy,and pyroptosis were decreased as well.After the administration of the ER stress inhibitor 4-phenyl-butyric acid,both mitophagy and pyroptosis were inhibited.Toyocamycin-induced XBP1 down-regulation decreased the levels of mitophagy and pyroptosis.The equilibrium between pyroptosis and mitophagy was disturbed by XBP1 accumulation.In summary,our findings confirmed that DEHP induced a ROS-mediated imbalance in pyroptosis and mitophagy in immature rat testes via XBP1.Moreover,XBP1 might be the key target in DEHP-related testis dysfunction. | Yifan Hong Xiazhu Zhou Qi Li Jing Chen Yuexin Wei Chunlan Long Lianju Shen Xiangqin Zheng Dinggang Li Xia Wang Chenjun Yu Shengde Wu Guanghui Wei | 2024 | Genes & Diseases2024，11，2： | 0 |
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