|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Maternal Eomesodermin regulates zygotic nodal gene expression for mesendoderm induction in zebrafish embryos显示文摘在在 midblastula 转变(MBT ) 的 zygotic 染色体激活前的动物胚胎的开发是实质上 supportedby 导出鸡蛋的母亲的产品。节的蛋白质在 MBT 以后是为中层和内胚叶正式就职的关键信号。Itremains 不清楚母亲的因素它在 zebrafish 胞胚的 ventrolateral blastodermal 边缘激活节的基因的 zygotic 表示。在这研究,我们显示出母亲的 Eomesodermina (Eomesa ) 的那损失,一个 T 盒子抄写因素,损害节的基因 ndr1 和 ndr2 以及 mesodermal 和 endodermal 标记的 zygotic 表示,在 mesendoderm 显示参与感应。母亲的 Eomesa 是为抄写因素基因 mxtx2 的及时 zygotic 表示的 alsorequired,节的基因表示的一个管理者。Eomesa 直接在激活他们的抄写的 ndr1, ndr2,和 mxtx2 的倡导者或 enhancer 绑在 Eomes 有约束力的地点。而且,节的基因也是的人和老鼠由 Eomes 调整了。进鼠科的胚胎的干细胞的 zebrafish eomesa 的 Transfection 与内长的节的表示的经常的高水平支持 mesendodermal 区别,建议 Eomes 的一个保存函数。一起拿,我们的调查结果在在脊椎动物胚胎调整节的基因表示和 mesendoderm 正式就职揭示母亲的 T-boxtranscription 因素的一个保存角色。 | Pengfei Xu Gaoyang Zhu Yixia Wang Jiawei Sun Xingfeng Liu Ye-Guang Chen Anming Meng | 2014 | Journal of Molecular Cell Biology2014，8，4： | 5 |
| 2 | PpINH1,an invertase inhibitor,interacts with vacuolar invertase PpVIN2 in regulating the chilling tolerance of peach fruit显示文摘Sucrose metabolism,particularly the decomposition of sucrose by invertase,plays a central role in plant responses to cold stress.Invertase inhibitors(INHs)evolved in higher plants as essential regulators of sucrose metabolism.By limiting invertase activity,INHs keep cellular sugar levels elevated,which provides enhanced protection to plants under stress.Our results showed that the expression of PpVIN2,the only vacuolar invertase(VIN)gene in peach fruit sensitive to chilling temperatures,increases significantly during cold storage,while VIN enzyme activity increases more modestly.We also found that peach fruit transiently overexpressing PpINH1 had decreased VIN activity.Interactions of PpINH1 and PpVIN2 with recombinant proteins were shown by yeast two-hybrid assays and bimolecular fluorescence complementation assays,as well as in vitro.During cold storage,trehalose-treated peach fruit had significantly increased PpINH1 expression,decreased VIN enzyme activity,and significantly higher sucrose content than did untreated fruit.As a result,the treated fruit had enhanced resistance to chilling injury.Collectively,our data show that the post-translational repression of VIN enzyme activity by PpINH1 helps maintain sucrose levels in peach fruit during cold storage,thereby improving resistance to chilling injury. | Xingxing Wang Yi Chen Shu Jiang Feng Xu Hongfei Wang Yingying Wei Xingfeng Shao | 2020 | Horticulture Research2020，7，1： | 1 |
| 3 | Evaluation of strategy for analyzing mouse liver plasma membrane proteome显示文摘Plasma membrane (PM) proteome is one of the major subproteomes present in the cell,and is very important in liver function. In the present work, C57 mouse liver PM was purified by density-gradient centrifugation. The purified PM was verified by electron microscope analysis and Western blotting. The results showed that the PM was enriched by more than 20-fold and the contamination of mitochondria was reduced by 2-fold compared with the homogenization fraction. Proteins were separated by 2DE and 1DE, trypsin-digested and submitted to ESI-Q-TOF and MALDI-TOF-TOF mass spectrometry or directly digested in solution and analyzed by LC-ESI ion trap mass spectrometry. In all, 547 non-redundant mouse liver PM proteins were identified, of which 34% contributed to plasma membrane or plasma membrane-related proteins. This study optimized and evaluated the HLPP plasma membrane proteome analysis method and made a systematic analysis on PM proteome. | CHEN Ping ZHANG LiJun LI XuanWen WANG XiE CAO Rui LIU Zhen XIONG JiXian PENG Xia WEI YingJuan YING XingFeng WANG XianChun LIANG SongPing | 2007 | Science China(Life Sciences)2007，50，6： | 1 |
| 4 | TIPE-mediated up-regulation of MMP-9 promotes colorectal cancer invasion and metastasis through MKK-3/p38/NF-κB pro-oncogenic signaling pathway显示文摘Dear Editor,Colorectal cancer(CRC)is the third most common malignant tumor in human,ranking third in cancer-related mortality.1 Most colon cancer patients die of metastasis.2 Intriguingly,the deregulation of tumor necrosis factorα‑induced protein 8(TIPE)has been shown to play a vital regulatory role in tumor cell growth,proliferation,invasion,and metastasis.3 TIPE is a kind of cytoplasmic protein of 23 kDa.A large number of studies have shown that TIPE is closely related to the development of colon cancer.4 In addition,decreased expression of TIPE was linked to down-regulation of matrix metallopeptidase-1(MMP-1),MMP-9,and vascular endothelial growth factor receptor-2 in breast cancer. | Huiyu Chen Yuhan Ye Yan Yang Mengya Zhong Lei Gu Zhaopu Han Jinhua Qiu Zhongchen Liu Xingfeng Qiu Guohong Zhuang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 1 |
| 5 | Initial research on the polarized reflectance of typical urban surface types measured by the Directional Polarimetric Camera显示文摘This paper retrieves the bidirectional polarization distribution functions (BPDFs) of the distinct urban cover in the Pearl River Delta (PRD) region employing the high spatial resolution of multi-angle polarized measurements made by the Directional Polarimetric Camera (DPC).The BPDF operational products of MICROPOL and POLDER measurements were used to validate the BPDF products of the DPC,with the results demonstrating that the BPDF product of the DPC measurements accurately expresses the surface polarized reflectance.The polarized reflectance of distinct surface types in the PRD region was studied using the DPC measurements.The results demonstrate that the polarized reflectances of different surface types differ and decrease as the normalized difference vegetation index increases.The polarized reflectance of a distinct surface type in the PRD region decreases with increasing scattering angle.The basic theory of investigating surface properties using multi-angle polarized measurements is proposed. | XIE DongHai GU XingFa CHENG TianHai YU Tao LI ZhengQiang CHEN XingFeng CHEN Hao GUO Jing | 2011 | Science China Earth Sciences2011，54，8： | 1 |
| 6 | Haspin氨基端非激酶域与Pds5B的结合在有丝分裂期保护着丝粒区姐妹染色体粘连显示文摘文章简介黏连蛋白复合体(cohesin)维持姐妹染色单体配对,并促进染色体与纺锤体的正确连接。在有丝分裂的初期,染色体臂上的cohesin在其调节亚基Wapl的作用下被大量地去除,而着丝粒区的cohesin必须得以保留才能防止染色体的错误分离。 | Linli Zhou Cai Liang Qinfu Chen Zhenlei Zhang Bo Zhang Haiyan Yan Feifei Qi Miao Zhang Qi Yi Youchen Guan Xingfeng Xiang Xiaoqing Zhang Sheng Ye 汪方炜 | 2018 | 科学新闻2018，0，4： | 0 |
| 7 | Spatiotemporal distribution of seasonal bird assemblages on land-bridge islands: linking dynamic and static views of metacommunities显示文摘Background: Although assessing temporal dynamics of populations is crucial for understanding metacommunities, empirical studies have primarily analyzed only static snapshots of communities. Here, we present a holistic view of how species traits and habitat characteristics relate to metacommunity dynamics and use it to test for differences in the spatiotemporal distribution of seasonal bird assemblages. Methods: We surveyed forest birds in breeding and winter seasons within 36 islands for 9 years. We then grouped birds into four landbird assemblages, selected on the basis of published differences in biology or ecology: winter residents, migratory winter visitors, breeding summer residents, and migratory summer visitors. We estimated dynamic species colonization and extirpation through the 9-year period, and evaluated the associations among island attributes, species attributes and community composition. Results: Overall, winter and summer residents showed strong associations between composition and habitat structure of the islands. In addition, winter and summer residents on large islands had lower extirpation and turnover than winter and summer visitors. Visitor assemblages showed no significant habitat associations, and in winter had high extirpation rates and small body sizes. By contrast, local extirpation of summer visitors was correlated with local species richness, indicating a likely effect of competition on extirpation. Conclusions: Our results demonstrated repeated patterns among species composition, bird traits, habitat/island characteristics and observed metacommunity dynamics. Winter and summer residents best matched species sorting and patch dynamics, respectively, due to differences in resource availability and requirements of overwinter survival versus breeding. Summer visitors were consistent with species sorting and winter visitors were randomly distributed, likely because of interactions with resident competitors. Our results highlight that coexisting seasonal migrant and resident assemblages differ in their spatial dynamics, with consequences for relevant conservation and management strategies. | Chuanwu Chen Marcel Holyoak Yanping Wang Xingfeng Si Ping Ding | 2019 | Avian Research2019，10，3： | 0 |
| 8 | Conceptual and theoretical dimensions of biodiversity research in China: examples from plants显示文摘The search for the underlying mechanisms of species origin,maintenance and extinction is among the highest priorities in biodiversity science.In parallel with the rapid accumulation of empirical evidence for existing theories in this field in China[1],numerous conceptual and theoretical achievements of basic biodiver sity science have been made,accompanied by methodological breakthroughs. | Chengjin Chu Lei Chen Pengfei Fan Ziwen He Yuanzhi Li Jinbao Liao Xubing Liu Kechang Niu Xingfeng Si Shaopeng Wang Xinqiang Xi | 2021 | National Science Review2021，8，7： | 0 |
| 9 | Spin Assignment for Yrast Levels ofOdd-odd ^(162)Lu Nucleus显示文摘Spin Assignment for Yrast Levels of Odd-odd ^(162)Lu Nucleus￥ZhangYuhu;ZhouXiaohong;ZhaoQingzhong;SunXiangfu;LeiXiangguo;GuoY?.. | Zhang Yuhu Zhou Xiaohong Zhao Qingzhong Sun Xiangfu Lei Xiangguo Guo Yingxiang Liu Zhong Chen Xingfeng Zhu Yongtai Wen Shuxian Yuan Guanjun and Liu Xiangan(Chinese Institute of Atomic Energy,Beijing.) | 1994 | IMP & HIRFL Annual Report1994，，0： | 0 |
| 10 | Strong Signature Dependence of Yrast Levels in ^(162)Lu显示文摘Strong Signature Dependence of Yrast Levels in^(162)Lu￥ZhangYuhu;ZhouXiaohong;ZhaoQingzhong;SunXiangfu;LeiXiangguo;GuoYingxia?.. | Zhang Yuhu Zhou Xiaohong Zhao Qingzhong Sun Xiangfu Lei Xiangguo Guo Yingxiang Liu Zhong Chen Xingfeng Zhu Yongtai Wen Shuxian Yuan Guanjun and Liu Xiangan(Chinese Institute of Atomic Energy,Beijing.) | 1994 | IMP & HIRFL Annual Report1994，，0： | 0 |
| 11 | First Observation of Yrast Band in N=91 Odd-odd ^(162)Lu Nucleus 显示文摘First Observation of Yrast Band in N=91 Odd-odd ^(162)Lu Nucleus￥ZhangYuhu;ZhouXiaohong;ZhaoQingzhong;SunXiangfu;LeiXiangguo;?.. | Zhang Yuhu Zhou Xiaohong Zhao Qingzhong Sun Xiangfu Lei Xiangguo Guo Yingxiang Liu Zhong Chen Xingfeng Zhu Yongtai Wen Shuxian Yuan Guanjun and Liu Xianan(Chinese Institute of Atomic Energy,Beijing.) | 1994 | IMP & HIRFL Annual Report1994，，0： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员