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| 1 | Post-appendectomy pelvic abscess with extended-spectrum beta-lactamase producing Escherichia coli : A case report and review of literature显示文摘BACKGROUND Appendicitis, the inflammation of the appendix, is the most common abdominal surgical emergency requiring expedient surgical intervention. Extendedspectrum beta-lactamases(ESBLs) are bacterial enzymes that catalyse the degradation of the betalactam ring of penicillins and cephalosporins(but without carbapenemase activity), leading to resistance of these bacteria to beta-lactam antibiotics. Recent increases in incidence of ESBL-producing bacteria have caused alarm worldwide. Proportion estimates of ESBLEnterobacteriaceae hover around 46% in China, 42% in East Africa, 12% in Germany, and 8% in the United States.CASE SUMMARY The impact of ESBL-producing bacteria on appendiceal abscesses and consequent pelvic abscesses are yet to be examined in depth. A literature review using the search words 'appendiceal abscesses' and 'ESBL Escherichia coli(E. coli)' revealed very few cases involving ESBL E. coli in any capacity in the context of appendiceal abscesses. This report describes the clinical aspects of a patient with appendicitis whodeveloped a postoperative pelvic abscess infected with ESBL-producing E. coli. In this report, we discuss the risk factors for contracting ESBL E. coli infection in appendicitis and post-appendectomy pelvis abscesses. We also discuss our management approach for postappendectomy ESBL E. coli pelvic abscesses, including drainage, pathogen identification, and pathogen characterisation. When ESBL E. coli is confirmed, carbapenem antibiotics should be promptly administered, as was done efficaciously with this patient. Our report is the first one in a developed country involving ESBL E. coli related surgical complications in association with a routine laparoscopic appendectomy.CONCLUSION Our report is the first involving ESBL E. coli and appendiceal abscesses, and that too consequent to laparoscopic appendectomy. | Andrew Tse Rajkumar Cheluvappa Selwyn Selvendran | 2018 | World Journal of Clinical Cases2018，6，16： | 2 |
| 2 | Endothelin and vascular remodelling in colitis pathogenesis—Appendicitis and appendectomy limit colitis by suppressing endothelin pathways显示文摘 | Rajkumar Cheluvappa Rajaraman Eri Annie S. Luo Michael C. Grimm | 2014 | International Journal of Colorectal Disease2014，，： | 1 |
| 3 | Modulation of interferon activity-associated soluble molecules by appendicitis and appendectomy limits colitis-identification of novel anti-colitic targets显示文摘 | Cheluvappa R Eri R Luo AS | 2015 | J Interferon Cytokine Res2015，35，2： | 1 |
| 4 | Endothelin and vascular remodelling in colitis pathogenesis-Appendieitis and appen- dectomy limit colitis by suppressing endothelin pathways显示文摘 | Cheluvappa R Eri R Luo AS | 2014 | Int J Colorectal Dis2014，29，11： | 1 |
| 5 | Increased ceruloplasmin and fibrinogen in type 2 diabetes corresponds to decreased anti-oxidant activity in a preliminary tertiary South Indi- an hospital study显示文摘 | Chacko SK Cheluvappa R | 2010 | Exp Clin Endocrinol Diabetes2010，118，1： | 1 |
| 6 | Reactions of Pseudo- monas aeruginosa pyocyanin with reduced Glutathione 显示文摘 | Cheluvappa R Shimmon R Dawson M | 2008 | Acta Bio- chimice Polonica2008，55，3： | 1 |
| 7 | Pseudomonas aeruginosa and the hyperlipidaemia of sepsis 显示文摘 | CHELUVAPPA R DENNING G M LAU G W | 2009 | Pathology2009，41，7： | 1 |
| 8 | A comprehensive evaluation of bladder cancer epidemiology and outcomes in Australia显示文摘 | Cheluvappa R Smith DP Cerimagic S | 2014 | International urology and nephrology2014，46，7： | 1 |
| 9 | Autophagy suppression by appendicitis and appendectomy protects against colitis显示文摘 | Cheluvappa R Luo AS Grimm MC | 2014 | Inflam Bowel Dis2014，20，5： | 1 |
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