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1Expression,deleton and mnutation of ρ16 gene in human gastric cancer显示文摘AIM To investigate the relationship between the expression of p16 gene and the gastric carcinogenesis,depth of invasion and lymph node metastases, and to evaluate the deletion and mutation of exon 2 in p16 gene in gastric carcinoma.METHODS The expression of P16 protein was examined by streptavidin-peroxidase conjugated method (S-P); the deletion and mutation of p16 gene were respectively examined by polymerase chain reaction (PCR) and polymerase chain reaction single-strand conformation polymorphism analysis (PCR-SSCP) in gastric carcinoma.RESULTS Expression of P16 protein was detected in 96.25% (77/80) of the normal gastric mucosa, in 92.00% (45/50) of the dysplastic gastric mucosa and in 47.54% (58/122) of the gastric carcinoma. The positive rate of P16 protein expression in gastric carcinoma was significantly lower than that in normal gastric mucosa and dysplastic gastric mucosa (P<0.05). The positive rate of P16 protein expression in mucoid carcinoma 10.00% (1/ 10) was significantly lower than that in poorly differentiated carcinoma 51.22% ( 21/ 41 ),undifferentiated carcinoma 57.69% (15/26) and signet ring cell carcinoma 62.50% (10/ 16) (P<0.05). The positive rate of p16 protein in 30 cases paired primary and lymph node metastatic gastric carcinoma: There was 46.67% (14/30) in primary gastric carcinoma, 16.67% (5/30) in lymph node metastatic gastric carcinoma. The positive rate of lymph node metastatic carcinoma was significantly lower than that of primary carcinoma (P<0.05). There was of p16 gene mutation in exon 2, but 5 cases displayed deletion of p16 gene in exon 2 in the 25 primary gastric carcinomas.CONCLUSIONS The expression loss of P16 protein related to the gastric carcinogenesis, gastric carcinoma histopathological subtypes and lymph metastasis. The mutation of p16 gene in exon 2 may not be involved in gastric carcinogenesis. But the deletion of p16 gene in exon 2 may be involved in gastric carcinogenesis.Xiu-Sheng He Qi Su Zhu-Chu Chen Xiu-Tao He Zhi-Feng Long Hui Ling Liang-Run Zhang Oncology Institute,Nanhua University,Hengyang 421001,Hunan Province,ChinaOncology Institute,Center South University,Changsha 410078,Hunan Province,China Department of Gastroenterology,First People’s Hospital of Changde City,Changde 415003,Hunan Province,China 2001World Journal of Gastroenterology2001,7,4:40
2Generation of GHZ-like and cluster-like quadripartite entangled states for continuous variable using a set of quadrature squeezed states显示文摘We designed the experimental generation system of the optical GHZ-like and cluster-like quadripartite entangled states for continuous variables.We theoretically demonstrated that the two different types of quadripartite entangled states can be obtained by the linearly optical transformation of four amplitude-quadrature and phase-quadrature squeezed states produced from a pair of nondegenerate optical parametric amplifiers under appropriate phase relations.The criteria for full inseparability of quadripartite cluster-like state were deduced,and the dependency of the quadripartite entanglement on the initial squeezing degree,the transmission efficiencies of the system and the detection efficiency of homodyne detection were numerically calculated.SU XiaoLong JIA XiaoJun XIE ChangDe PENG KunChi 2008Science China(Physics,Mechanics & Astronomy)2008,51,1:12
3Grey GM(1,1) Model with Function-Transfer Method for Wear Trend Prediction and its Application显示文摘Trend forecasting is an important aspect in fault diagnosis and work state supervision. The principle, where Grey theory is applied in fault forecasting, is that the forecast system is considered as a Grey system; the existing known information is used to infer the unknown information’s character, state and development trend in a fault pattern, and to make possible forecasting and decisions for future development. It involves the whitenization of a Grey process. But the traditional equal time interval Grey GM (1,1) model requires equal interval data and needs to bring about accumulating addition generation and reversion calculations. Its calculation is very complex. However, the non equal interval Grey GM (1,1) model decreases the condition of the primitive data when establishing a model, but its requirement is still higher and the data were pre processed. The abrasion primitive data of plant could not always satisfy these modeling requirements. Therefore, it establishes a division method suited for general data modeling and estimating parameters of GM (1,1), the standard error coefficient that was applied to judge accuracy height of the model was put forward; further, the function transform to forecast plant abrasion trend and assess GM (1,1) parameter was established. These two models need not pre process the primitive data. It is not only suited for equal interval data modeling, but also for non equal interval data modeling. Its calculation is simple and convenient to use. The oil spectrum analysis acted as an example. The two GM (1,1) models put forward in this paper and the new information model and its comprehensive usage were investigated. The example shows that the two models are simple and practical, and worth expanding and applying in plant fault diagnosis.LUO You xin 1 , PENG Zhu 2 , ZHANG Long ting 1 , GUO Hui xin 1 , CAI An hui 1 1Department of Mechanical Engineering, Changde Teachers University, Changde 415003, P.R. China 2 Engineering Technology Board, Changsha Cigare 2001International Journal of Plant Engineering and Management2001,6,4:11
4Translation and psychometric evaluation of the Chinese version of the Heart Failure-Specific Health Literacy Scale显示文摘Objective:Health literacy is closely associated with self-care behaviors in heart-failure patient.A reliable,valid,and practical measuring tool would evaluated the level of health literacy in Chinese patients with heart failure,and provide evidence for individualized education.Aim of this study was to translate Heart Failure-Specific Health Literacy Scale(HF-Specific HL Scale)into Chinese and test the reliability and validity of the Chinese version.Methods:The original HF-specific HL scale was translated into Chinese and modified for cultural adaption.Totally 164 HF inpatients were investigated with the Chinese version of HF-specific HL scale.To test the reliability and validity of the scale,item analysis,exploratory factor analysis(EFA),confirmatory factor analysis(CFA),and correlation analysis were conducted.Result:Cronbach's a value for the scale is 0.87;the correlation coefficients between each item and the total score ranged from 0.61 to 0.91.Three factors was extracted by EFA,which could explain 64.62%of the total variance.The result of CFA also showed that the scale demonstrated an acceptable model fit.The scale was significantly correlated with the Chinese version of the Heart Failure Knowledge Test(C-HFKT).Conclusion:The Chinese version of HF-specific HL scale is reliable and valid,and is suitable for assessment of HL in Chinese HF patients.Meng Yue Lijun Zhang Yuanyuan Lu Changde Jin 2016International Journal of Nursing Sciences2016,3,4:10
5Grey Problems of a Mechanical Transmission System in a Reliability Study显示文摘In the light of the Grey characters of reliability on a mechanical transmission system, Grey problems that could assist in the study on mechanical transmission system were analyzed. For example, the factors of time function,the factors of environment and the factors of people have some relationships with the system in this paper. And then, the methods and procedures, which were based upon the theory of Grey system, were elaborated.LUO You-xin, CAI An-hui, ZHANG Long-ting, GUO Hui-xin Department of Mechanical Engineering, Changde Normal College, Changde 415003, P. R. China 2001International Journal of Plant Engineering and Management2001,6,2:8
6The relationship between internal domain sequences ofpiggyBac and its transposition efficiency in BmN ceils and Bombyx mori显示文摘piggyBac transposon,它包括终端转换了重复序列和内部领域(标志) 序列,广泛地为昆虫转变被用作一个工具。为关于 Bombyx mori 的转基因的研究优化这个系统,我们在绿色的表达式上检验了 transposase plasmid 和它的标志序列的数量的效果荧光灯蛋白质(GFP ) 。四种 transposon plasmids , pB [ A3GFP ]有标志的完整的长度的 -1 定序, pB [ A3GFP ]有 3 仅仅标志顺序的 -2 , pB [ A3GFP ]没有标志序列的 -3 ,和 pB [ A3GFP ]包含 5 标志顺序的 333 bp 的 -4 ,并且 3 标志顺序的 179 bp 作为标记与 GFP 被构造。在 transfecting 以后这四 plasmids 进 BmN 房间,我们由比较对否定房间比率积极的 GFP 分析了 transfecting 效率。我们的结果显示 plasmid pB-4 在第 22 天得到了最高的比率。而且,没有生产过剩抑制,对否定房间比率积极的 GFP 与 transposase plasmid 的更高的数量增加了。而且,我们注射了三 piggyBac transposon plasmids, pB [A3GFP ]-1, pBLanfang Zhuang Hao Wei Changde Lu Boxiong Zhong 2010Acta Biochimica et Biophysica Sinica2010,42,6:7
7Grey System Judgment on Reliability of Mechanical Equipment显示文摘The Grey system theory was applied in reliability analysis of mechanical equipment.It is a new theory and method in reliability engineering of mechanical engineering of mechanical equipment. Through the Grey forecast of reliability parameters and the reliability forecast of parts and systems, decisions were made in the real operative state of equipment in real time. It replaced the old method that required mathematics and physical statistics in a large base of test data to obtain a pre check, and it was used in a practical problem. Because of applying the data of practical operation state in real time, it could much more approach the real condition of equipment; it was applied to guide the procedure and had rather considerable economic and social benefits.LUO You xin, GUO Hui xin, ZHANG Long ting, CAI An hui, PENG Zhu Department of Mechanical Engineering,Changde Teachers University, Changde 415003, P.R.China 2001International Journal of Plant Engineering and Management2001,6,3:7
8The central black hole masses for the γ-ray loud blazars显示文摘The Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope (formerly GLAST) provides an increase in sensitivity and has detected rapid variability of gamma-ray sources.The variability time scales detected from the gamma-ray loud blazars by LAT and EGRET,and gamma-ray luminosity are used to estimate the central black hole masses.In this work,we find that the lower limits of central black hole masses are in a range of (0.3-24)×107M⊙,which are compared with those obtained by other authors.Our results are consistent with other authors' results.Also,the Lorentz factor,Γ,and the propagation angle,θ,are obtained for 18 blazars for which superluminal motions are known.YANG JiangHe1,2* & FAN JunHui2,3 1 Department of Physics and Electronics Science,Hunan University of Arts and Science,Changde 415000,China 2 Center for Astrophysics,Guangzhou University,Guangzhou 510405,China 3 Key Laboratory of Astronomy Observation and Technology,Guangzhou University,Guangzhou 510405,China 2010Science China(Physics,Mechanics & Astronomy)2010,53,10:6
9Vehicle License Plate Character Segmentation显示文摘Vehicle license plate (VLP) character segmentation is an important part of the vehicle license plate recognition system (VLPRS). This paper proposes a least square method (LSM) to treat horizontal tilt and vertical tilt in VLP images. Auxiliary lines are added into the image (or the tilt-corrected image) to make the separated parts of each Chinese character to be an interconnected region. The noise regions will be eliminated after two fusing images are merged according to the minimum principle of gray values.Then, the characters are segmented by projection method (PM) and the final character images are obtained. The experimental results show that this method features fast processing and good performance in segmentation.Mei-Sen Pan~(1,*) Jun-Biao Yan~1 Zheng-Hong Xiao~(1,2) 1 Department of Computer Science and Technology, Hunan University of Arts and Science, Changde 415000, PRC 2 School of Information Science and Engineering, Central South University, Changsha 400083, PRC 2008International Journal of Automation and computing2008,5,4:5
10The line emissions and polarization in blazars显示文摘The correlations between broad-line emission,polarization,and core-dominance parameters are investigated for a sample of 148 blazars(BL Lacertae objects-BLs and flat spectrum radio quasars-FSRQs). An anti-correlation between the broad-line luminosity and the linear polarization is found. The broad-line and polarization relation can be explained by using a relativistic beaming model,which perhaps suggests that BL Lacs and FSRQs are a single class. We also investigated the relation between the ratio of the broad-line luminosity to the Eddington luminosity and linear polarization,and that between the ratio of the broad-line luminosity to the Eddington luminosity and the core-dominance parameter.YANG JiangHe 1,2 ,FAN JunHui 2,3 & YANG RuShu 1 1 Department of Physics and Electronics Science,Hunan University of Arts and Science,Changde 415000,China 2 Center for Astrophysics,Guangzhou University,Guangzhou 510405,China 3 Key Laboratory of Astronomy Observation and Technology,Guangzhou University,Guangzhou 510405,China 2010Science China(Physics,Mechanics & Astronomy)2010,53,6:4
11Quantum storage of optical signals and coherent manipulation of quantum states based on electromagnetically induced transparency显示文摘Electromagnetically induced transparency (EIT) techniques are important tools for the storage of the quantum states of light fields in atomic ensembles and for enhancement of the interaction between photons. In this paper, we briefly summarize the recent experimental studies conducted by our group on enhanced cross-phase modulation based on double EIT effects, the quantum interference of stored dual-channel spin-wave excitations and the coherent manipulation of the spin wave vector for the polarization of photons in a single tripod atomic system. The work presented here has potential application in the developing field of quantum information processing.WANG Hai XIE ChangDe PENG KunChi 2012Chinese Science Bulletin2012,57,16:4
12Preparation of multipartite entangled states used for quantum information networks显示文摘The preparation of multipartite entangled states is the prerequisite for exploring quantum information networks and quantum computation.In this paper,we review the experimental progress in the preparation of cluster states and multi-color entangled states with continuous variables.The preparation of lager scale multipartite entangled state provide valuable quantum resources to implement more complex quantum informational tasks.SU XiaoLong JIA XiaoJun XIE ChangDe PENG KunChi 2014Science China(Physics,Mechanics & Astronomy)2014,57,7:4
13Quantum network based on non-classical light显示文摘Quantum network enables quantum communication among quantum nodes and provides advantages that are unavailable in any classical network.Based on rapidly developing science and technology in quantum communication,the studies on quantum network have also made important progresses recent years.In this study,we briefly review the experimental progresses in building quantum network based on optical field and discuss the challenges toward a quantum Internet.Xiaolong SU Meihong WANG Zhihui YAN Xiaojun JIA Changde XIE Kunchi PENG 2020Science China(Information Sciences)2020,63,8:3
14The Significance of MMP-9 Over MMP-2 in HCC Invasiveness and Recurrence of Hepatocellular Carcinoma After Curative Resection显示文摘Rongxin Chen Jiefeng Cui Changde Xu Tongchun Xue Kun Guo Dongmei Gao Yinkun Liu Shenglong Ye Zhenggang Ren 2012Annals of Surgical Oncology2012,,3:2
15Deadbands and the Dynamic Response and Performance of Large Water Transfer Canal System显示文摘An operating simulation mode for multireach canal system in series under gate regulating is established. The discharge feedforward plus water lever feedback PID controller was adopted. And the performance indicators are introduced to evaluate the control effects of canal operation. Influence on dynamic response process and dynamic performance as well as the control actions of canal system are studied according to the variation of the gate deadband and water level deadband. The results showed that the larger the gate deadband, the worse, the control effect of canal system over water level, and so done the stable process of gate discharge, yet the stable process of gate opening was getting better, while the upstream gate regulation of each canal pool was less at the time when canal stabilizes; the closer to downstream end of canal, the lager steady-state error of this canal pool was, and the lager influence of gate deadband on the steady-state error as well as response time of this canal pool was; the canal system can not acquire superiority in both the control performance and control actions when only the water level deadband was established.DING Zhiliang WANG Changde TAN Guangming GUAN Guanghua 2009Journal of Northeast Agricultural University(English Edition)2009,16,2:2
16Quantum variances and squeezing of output field from NOPA 显示文摘 SU Hong XIE Changde 1999Phys Lett A1999,259,:1
17IsEastAsiaFitforanOptimumCurrencyArea-AnAssessmentoftheEconomicFeasibilityofaHigherDegreeofMonetaryCooperationinEastAsia显示文摘AhnC KimHB ChangD 2006TheDevelopingEconomics2006,,44:1
18Design of integrated amorphous-silicon thin-film transistor gate driver显示文摘Liao Congwei He Changde 2013Journal of Display Teehnology2013,9,1:1
19Modeling, simulation and automatic control of long distance water transfer in winter 显示文摘Liu Guoqiang Wang Changde Guan Guanghua 2011Advanced Materials Research2011,304,:1
20An efficient method for inverse dynamics of manipulators based on the virtual work principle 显示文摘Zhang Changde Song Shinmin 1993Journal of Robotics Systems1993,10,5:1
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