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| 1 | 基于胜任力模型培养护士长领导力的效果研究显示文摘目的探讨基于胜任力模型培养护士长领导力的效果。方法选取22名护士长进行为期3年的岗位领导力培训,包括成立管理委员会、论证护士长领导力以及基于胜任力模型的沟通和关系管理、临床实践知识、职业水准、经营知识和技能等方面培训内容的构建,研究结束后,比较护士长培训前后的领导力及护士对护士长的满意度。结果培训后,护士长的领导力各维度得分提高,护士对护士长的满意度各条目得分均提高。结论以护理管理者胜任力模型为基础的护理管理培训和实践可以有效提升护士长的岗位胜任力。 | 侯艳 沈晓雁 张异凡 陈立新 邢广军 Chanell Carcallas Concepcion | 2018 | 护理管理杂志2018，18，10： | 20 |
| 2 | The role of the N-methyl-D-aspartate receptor in the proliferation of adult hippocampal neural stem and precursor cells显示文摘New neurons are continuously generated from resident pools of neural stem and precursor cells(NSPCs)in the adult brain.There are multiple pathways through which adult neurogenesis is regulated,and here we review the role of the N-methyl-D-aspartate receptor(NMDAR)in regulating the proliferation of NSPCs in the adult hippocampus.Hippocampal-dependent learning tasks,enriched environments,running,and activity-dependent synaptic plasticity,all potently up-regulate hippocampal NSPC proliferation.We first consider the requirement of the NMDAR in activity-dependent synaptic plasticity,and the role the induction of synaptic plasticity has in regulating NSPCs and newborn neurons.We address how specific NMDAR agonists and antagonists modulate proliferation,both in vivo and in vitro,and then review the evidence supporting the hypothesis that NMDARs are present on NSPCs.We believe it is important to understand the mechanisms underlying the activation of adult neurogenesis,given the potential that endogenous stem cell populations have for repopulating the hippocampus with functional new neurons.In conditions such as age-related memory decline,neurodegeneration and psychiatric disease,mature neurons are lost or become defective;as such,stimulating adult neurogenesis may provide a therapeutic strategy to overcome these conditions. | TAYLOR Chanel J HE RongQiao BARTLETT Perry F | 2014 | Science China(Life Sciences)2014，57，4： | 6 |
| 3 | Autofocus for automated microassembly under a microscope显示文摘 | ALLEGRO S CHANEL C JACOT J | 1996 | Journal of Image Processing1996，2，10： | 1 |
| 4 | Leukocytosisi and the retinoic acid syndrome in patient swith acute promyelocytic leukemia treated with arsenic trioxide显示文摘 | Camacho LH Soignet S L Chanel S | 2000 | Clin Oncol2000，18，13： | 1 |
| 5 | Leukocytosis and the reti-noic acid syndrome in patients with acute promyelocytic Leukemiatreated widi arsenic trioxide显示文摘 | Cmacho LH Soignet SL Chanel S | 2000 | J Clin oncol2000，18，： | 1 |
| 6 | Hydrosalpinx and infertility: what about conservative surgical management? 显示文摘 | Chanelles O Ducarme G Sifer C | 2011 | Eur J Obstet Gynecol Reprod Biol2011，159，1： | 1 |
| 7 | Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome显示文摘 | Maslak P Chanel S Camacho LH | 2006 | Leukemia2006，20，2： | 1 |
| 8 | How to prevent postoperative in- trauterine adhesions显示文摘 | Frey C Chanelles O Poncelet C | 2010 | Gynecol Obstet Fertil2010，38，9： | 1 |
| 9 | Synchronous pulmonary adenocarcinoma and extranodal marginal zona/low-grade B-cell lymphoma of MALT type显示文摘 | Burke L Fiche M | 2001 | Human Pathology2001，32，1： | 1 |
| 10 | The relevance of hedonic price indices显示文摘 | Olivier Chanel Louis-André Gérard-Varet Victor Ginsburgh | 1996 | Journal of Cultural Economics1996，，1： | 1 |
| 11 | Effects of 17-allylamino-17-demethoxygeldanamycin (17-AAG) in transgenic mouse models of frontotemporal lobar degeneration and Alzheimer’s disease显示文摘Alzheimer’s disease(AD),the most common dementia,is characterized by potentially neurotoxic aggregation of Aβ peptide and tau protein,and their deposition as amyloid plaques and neurofibrillary tangles(NFTs).Tau aggregation also occurs in other common neurodegenerative diseases.Frontotemporal dementia(FTD)can be caused by tau mutations that increase the susceptibility of tau to hyperphosphorylation and aggregation,which may cause neuronal dysfunction and deposition of NFTs.17-allylamino-17-demethoxygeldanamycin(17-AAG)is a potent inhibitor of heat shock protein 90(Hsp90),a cytosolic chaperone implicated in the proper folding and functions of a repertoire of client proteins.17-AAG binds to Hsp90 and enhances degradation of Hsp90 client protein.We sought to determine whether 17-AAG can reduce Aβ and tau pathology in the brains of AD and FTD model mice expressing Aβ or P301L mutant tau,respectively.Mice were randomized to receive 25,5,or 0 mg/kg 17-AAG thrice weekly from age eight to 11 months.Analysis was performed by rotarod test on motor function,on the area occupied by plaques in hippocampus or NFTs in medulla tissue sections,and on mortality.A high dose of 17-AAG tended to decrease NFTs in male mice(p=0.08).Further studies are required to confirm the effect of 17-AAG in diseases of tau aggregation. | Shuk Wai Ho Yuk Tung Chanel Tsui Ting Ting Wong Stanley Kwok-Kuen Cheung William B Goggins Lau Ming Yi Kwok Kin Cheng Larry Baum | 2013 | Translational Neurodegeneration2013，2，1： | 1 |
| 12 | Leukocytosis and the retinoic acid syndrome in patients with acute promyelocytic leukemia treated with arsenic trioxide 显示文摘 | Camacho L H Soignet S L Chanel S | 2000 | J Clin Oncol2000，18，13： | 1 |
| 13 | Leukocytosis and the retinoic acid syndrome in patients with acute promyelocytic leukemia treated with arsenic trioxide 显示文摘 | Camacho LH Soignet SL Chanel S | 2000 | J Clin Oncol2000，18，13： | 1 |
| 14 | Public-health impact of outdoor and traffic-related air pollution: a European assessment显示文摘 | N Künzli R Kaiser S Medina M Studnicka O Chanel P Filliger M Herry F Horak V Puybonnieux-Texier P Quénel J Schneider R Seethaler J-C Vergnaud H Sommer | 2000 | The Lancet2000，，9232： | 1 |
| 15 | Autofocus for automated microassembly under a microscope显示文摘 | Allegro S Chanel C Jacot J | 1996 | Image Processing1996，，1： | 1 |
| 16 | Autofocus for automated microassembly under a microscope显示文摘 | Allegro S Chanel C Jacot J | 1996 | Image Processing1996，，1： | 1 |
| 17 | Is art market behaviour predictable?显示文摘 | Olivier Chanel | 1995 | European Economic Review1995，，3： | 1 |
| 18 | Influence of pyrolysis temperature on biochar property andfunction as a heavy metal sorbent in soil显示文摘 | Minori U Lynda H W K Thomas K Chanel A F Isabel M L | 2011 | Journal of Agricultural and Food Chemistry2011，59，： | 1 |
| 19 | Hydrosalpinx and infertility:what about conservative surgical management显示文摘 | Olivier Chanelles Guillaume Ducarme Christophe Sifer | 2011 | Euro- pean Journal of Obstetrics & Gynecology and Reproductive Biology2011，159，1： | 1 |
| 20 | Autofocus for auto- mated microassembly under a microscope显示文摘 | Allegro S Chanel C Jacot J | 1996 | Jour- nal of Image Processing1996，，11： | 1 |
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