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5篇 您的检索式:作者名="Chanchevalap"
    题名 作者 年代 出处 被引量
1Krüppel-like factors 4 and 5:the yin and yang regulators of cellular proliferation显示文摘Krüppel-like factors (KLFs) are evolutionarily conserved zinc finger-containing transcription factors with diverseregulatory functions in cell growth, proliferation, differentiation, and embryogenesis. KLF4 and KLF5 are two closelyrelated members of the KLF family that have a similar tissue distribution in embryos and adults. However, the two KLFsoften exhibit opposite effects on regulation of gene transcription, despite binding to similar, if not identical, cis-actingDNA sequences. In addition, KLF4 and 5 exert contrasting effects on cell proliferation in many instances; while KLF4is an inhibitor of cell growth, KLF5 stimulates proliferation. Here we review the biological properties and biochemicalmechanisms of action of the two KLFs in the context of growth regulation.Amr M.GHALEB Mandayam O.NANDAN Sengthong CHANCHEVALAP W.Brian DALTON Irfan M.HISAMUDDIN Vincent W.YANG 2005Cell Research2005,15,2:21
2All-trans retinoic acid inhibits proliferation on intestinal epithelial cells by inhibiting expression of the gene encoding Krüppel-like factor 5显示文摘CHANCHEVALAP S NANDAN M O MERLIN D 0,,1:1
3All- trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Krüppel-like factor 5显示文摘Sengthong Chanchevalap Mandayam O. Nandan Didier Merlin Vincent W. Yang 2004FEBS Letters2004,,1:1
4Kruppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells 显示文摘Chanchevalap S Nandan MO McConnell BB 2006Nucleic Acids Res2006,34,4:1
5All-trans retinoic acid inhibits proliferation of intestional epithelial cells by inhibiting expresstion of the gene encoding Krüpple-like factor 5显示文摘Chanchevalap SNM Merlin D Yang VW 2004FEBS Lett2004,578,12:1
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