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| 1 | The efficacy of fluoropyrimidine.based adjuvant chemotherapy on biliary tract cancer after R0 resection显示文摘Background: The optimal treatment strategy for biliary tract cancer(BTC) after curative?intent resection remains con?troversial. The purpose of this study was to evaluate the efficacy of fluoropyrimidine?based adjuvant chemotherapy for BTC patients undergoing microscopically margin?negative(R0) resection.Methods: We retrospectively analyzed the clinical data of BTC patients who underwent curative?intent R0 resection. Patients were eligible if they received either fluoropyrimidine?based adjuvant chemotherapy or observation after R0 resection.Results: A total of 153 patients were included. In the entire patient cohort, no significant differences were observed in 5?year overall survival(OS) rates(48.4% vs. 39.6%, P = 0.439) or 3?year recurrence?free survival(RFS) rates(49.1% vs. 39.5%, P = 0.299) between patients who received fluoropyrimidine?based adjuvant chemotherapy or observation. However, for patients with stages Ⅱ and Ⅲ BTC, chemotherapy significantly improved 5?year OS rate(52.4% vs. 35.6%, P = 0.002) and 3?year RFS rate(55.5% vs. 39.1%, P = 0.021) compared with observation.Conclusion: Fluoropyrimidine?based adjuvant chemotherapy may prolong the survival of patients with stages Ⅱ and Ⅲ BTC after R0 resection. | Young Saing Kim Chi-Young Jeong Haa-Na Song Tae Hyo Kim Hong Jun Kim Young-Joon Lee Soon Chan Hong | 2017 | Chinese Journal of Cancer2017，36，5： | 2 |
| 2 | Characterization of a new porous tantalum biomaterial for reconstructive orthopaedics显示文摘 | Bobyn JD Hacking SA Chan SP | 1999 | American Academy of Orthopaedic Surgeons1999，2，： | 1 |
| 3 | Determination of aristolchic acid in medicinal plant and herbal product by liquid chromatography -electrospray-ion trap mass spectrometry显示文摘 | Chan SA Chen MJ Liu TY | 2003 | Talanta2003，60，： | 1 |
| 4 | Quantitative analysis of isoflavone aglycones in human serum by solid phase extraction and liquid chromatography-tandem mass spectrometry 显示文摘 | Chan SA Lin SW Yu KJ | 2006 | Talanta2006，69，4： | 1 |
| 5 | Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/-mice:evidence for independent chemokine functions in atherogenesis显示文摘 | Saederup N Chan L Lira SA | 2008 | Circulation2008，117，13： | 1 |
| 6 | A new bieyelie guanidine alkaloid, Seh 575948, from a marine sponge, Ptilocaulis spiculifer显示文摘 | Yang SW Chan TM Pomponi SA | 2003 | J Antibiot (Tokyo)2003，56，11： | 1 |
| 7 | Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis显示文摘 | Hinchey J Lee S Jeon BY Basaraba RJ Venkataswamy MM Chen B Chan J Braunstein M Orme IM Derrick SC Morris SL Jacobs WR Jr Porcelli SA | 2007 | J Clin Invest2007，117，8： | 1 |
| 8 | Liver transplantation in infants 显示文摘 | Saing H Fan ST Chan KL | 1999 | J Pediatr Surg1999，34，11： | 1 |
| 9 | A study of pre-antibiotic bacteriology in 125 patients with neerotizing enterocolitis显示文摘 | Chan KL Saing H Yung RW | 1994 | Acta Paediatr Suppl1994，396，： | 1 |
| 10 | Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/-mice: evidence for independent chemokine functions in atherogenesis显示文摘 | Saederup N Chan L Lira SA Charo IF | 2008 | Circulation2008，117，13： | 1 |
| 11 | Aspirin use, body mass index,physical activity,plasma C-peptide,and colon cancer risk in US health professionals 显示文摘 | ZHang X Smith-Warner SA Chan AT | 2011 | Am J Epidemiol2011，174，4： | 1 |
| 12 | The regeneration of transected sciatic nerves of adult rats using chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells显示文摘 | Qiang Ao Chun-Kit Fung Alex Yat-Ping Tsui Sa Cai Huan-Cong Zuo Ying-Shing Chan Daisy Kwok-Yan Shum | 2010 | Biomaterials2010，，3： | 1 |
| 13 | Choline kinasealpha and hexokinase-2 protein expression in hepatocellularcarcinoma: association with survival显示文摘 | Kwee SA Hernandez B Chan 0 | 2012 | PLOS One2012，7，46： | 1 |
| 14 | Clinical presentation of cervical ribs in the pediatric population显示文摘 | Chan KH Gitomer SA Perkins JN | | 0，，03： | 1 |
| 15 | Cytotoxic Activity of Kenaf Seed Oils from Supercritical Carbon Dioxide Fluid Extraction towards Human Colorectal Cancer (HT29) Cell Lines显示文摘 | Abd Ghafar SA Ismail M Yazan LS Fakurazi S Ismail N Chan KW Tahir PM | 2013 | Evidence- Based Complementary and Alternative Medicine2013，，： | 1 |
| 16 | POINeT: protein interactome withsub-network analysis and hub prioritization 显示文摘 | Lee SA Chan CH Chen TC | 2009 | BMC Bioinformatics2009，2110，： | 1 |
| 17 | Thyroid dysfunction in chronic schizophrenia within a psychiatric hospital显示文摘 | Sim K Chong SA Chan YH | 2002 | Ann Acad Med Singapore2002，31，5： | 1 |
| 18 | Determination of aristolochic acids in medicinal plant and herbal product by liquid chromatography-electrospray-ion trap mass spectrometry显示文摘 | Chan Sa Chen MJ Liu Ty | 2003 | Talanta2003，60，4： | 1 |
| 19 | Incorporation of NKT cell-activating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis bacillus Calmette-Guerin显示文摘 | Venkataswamy MM Baena A Goldberg MF Bricard G Im JS Chan J Reddington F Besra GS Jacobs WR Jr Porcelli SA | 2009 | J Immnnol2009，183，3： | 1 |
| 20 | Ventricu- lar rate determines early bradycardic electrical remodeling 显示文摘 | Suto F Zhu W Chan SA | 2005 | Heart Rhythm2005，2，3： | 1 |
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