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| 1 | Comparative effectiveness of i-SCAN^(TM) and high-definition white light characterizing small colonic polyps显示文摘AIM:To evaluate accuracy of in vivo diagnosis of adenomatous vs non-adenomatous polyps using i-SCAN digital chromoendoscopy compared with high-definition white light.METHODS:This is a single-center comparative effectiveness pilot study.Polyps(n = 103) from 75 averagerisk adult outpatients undergoing screening or surveillance colonoscopy between December 1,2010 and April 1,2011 were evaluated by two participating endoscopists in an academic outpatient endoscopy center.Polyps were evaluated both with high-definition white light and with i-SCAN to make an in vivo prediction of adenomatous vs non-adenomatous pathology.We determined diagnostic characteristics of i-SCAN and highdefinition white light,including sensitivity,specificity,and accuracy,with regards to identifying adenomatous vs non-adenomatous polyps.Histopathologic diagnosis was the gold standard comparison.RESULTS:One hundred and three small polyps,detected from forty-three patients,were included in the analysis.The average size of the polyps evaluated in the analysis was 3.7 mm(SD 1.3 mm,range 2 mm to 8 mm).Formal histopathology revealed that 54/103(52.4%) were adenomas,26/103(25.2%) were hyperplastic,and 23/103(22.3%) were other diagnoses include 'lymphoid aggregates','non-specific colitis,' and 'no pathologic diagnosis.' Overall,the combined accuracy of endoscopists for predicting adenomas was identical between i-SCAN(71.8%,95%CI:62.1%-80.3%) and high-definition white light(71.8%,95%CI:62.1%-80.3%).However,the accuracy of each endoscopist differed substantially,where endoscopist A demonstrated 63.0% overall accuracy(95%CI:50.9%-74.0%) as compared with endoscopist B demonstrating 93.3% overall accuracy(95%CI:77.9%-99.2%),irrespective of imaging modality.Neither endoscopist demonstrated a significant learning effect with i-SCAN during the study.Though endoscopist A increased accuracy using i-SCAN from 59%(95%CI:42.1%-74.4%) in the first half to 67.6%(95%CI:49.5%-82.6%) in the second half,and endoscopist B decreased accuracy using i-SCAN from 100%(95%CI:80.5%-100.0%) in the first half to 84.6%(95%CI:54.6%-98.1%) in the second half,neither of these differences were statistically significant.CONCLUSION:i-SCAN and high-definition white light had similar efficacy predicting polyp histology.Endoscopist training likely plays a critical role in diagnostic test characteristics and deserves further study. | Johanna L Chan Li Lin Michael Feiler Andrew I Wolf Diana M Cardona Ziad F Gellad | 2012 | World Journal of Gastroenterology2012，18，41： | 3 |
| 2 | PECS: Towards Personalized Edge Caching for Future Service-Centric Networks显示文摘Mobile operators face the challenge of how to best design a service-centric network that can effectively process the rapidly increasing number of bandwidth-intensive user requests while providing a higher quality of experience(QoE). Existing content distribution networks(CDN) and mobile content distribution networks(mCDN) have both latency and throughput limitations due to being multiple network hops away from end-users. Here, we first propose a new Personalized Edge Caching System(PECS) architecture that employs big data analytics and mobile edge caching to provide personalized service access at the edge of the mobile network. Based on the proposed system architecture, the edge caching strategy based on user behavior and trajectory is analyzed. Employing our proposed PECS strategies, we use data mining algorithms to analyze the personalized trajectory and service usage patterns. Our findings provide guidance on how key technologies of PECS can be employed for current and future networks. Finally, we highlight the challenges associated with realizing such a system in 5G and beyond. | Ming Yan Wenwen Li Chien Aun Chan Sen Bian Chih-Lin I André F. Gygax | 2019 | China Communications2019，16，8： | 3 |
| 3 | 应对RoHS指令的测试方法、应用及其挑战显示文摘本文简要介绍了香港绿色制造测试中心根据美国环境保护协会(EPA)测试指南进行检测的基本步骤和应用。同时,简要示例了两个相应的测试结果。最后提及了面临的问题和挑战。 | A. Tso i S. C. Tan A. Wong 钟伟 邬博义 Y. C. Chan | 2006 | 电子质量2006，，7： | 2 |
| 4 | Efficacy of transient elastography in screening for large esophageal varices in patients with suspicious or proven liver cirrhosis显示文摘 | Huay‐Min WANG Gin‐Ho LO Wen‐Chi CHEN Ping‐I HSU Hsien‐Chung YU Chiun‐Ku LIN Hoi‐Hung CHAN Wei‐Lun TSAI Feng‐Woei TSAY Tsan‐Ping LIU E‐Ming WANG Kwok‐Hung LAI | 2012 | Journal of Digestive Diseases2012，，8： | 2 |
| 5 | 用接收函数研究中国地壳结构显示文摘收集处理了中国国家数字地震台网(CNDSN)48个地震台记录的大量高质量的宽频带远震波形资料,用于计算中国大尺度的地壳厚度横向变化和VP/VS值(泊松比)变化。用一种统计方法来挑选每个台站的互相关接收函数,多数台站的记录在200条以上。由常用的H-к(地壳厚度和VP/VS值)方法可以发现H和к之间有明显的折衷关系。因此在H-к域内,经常出现多个极大值。为了减少这种折衷,这里引入一种权重函数,用它计算出每个H-к网格上PS转换震相与反射震相的相关性。用四次方根叠加方法进一步降低线性叠加带来的不相关噪声。在减少H-к折衷方面,这种修改后的方法非常有效,得出了可靠的地壳厚度值和VP/VS值。在中国东部的地壳厚度为31~33km,莫霍界面相对平坦和清晰。在中国西部,地壳相对较厚,地形变化很大。天山褶皱带的莫霍界面厚度为51km,青藏高原中部的莫霍界面厚度达84km。在东经100°到110°之间,所谓的南北带上发生了过渡转变,此地区表现为频繁的地震活动和明显的重力异常。中国大陆地壳的VP/VS平均值约为1.730(σ=0.249),比全球大陆地壳的平均值1.78(σ=0.27)低很多。较低的VP/VS值意味着在中国大陆的地壳最低层中缺少镁铁层。 | Hrvoje Tkali Winston Chan 许若冰 | 2010 | 世界地震译丛2010，41，6： | 2 |
| 6 | Direct demonstration of an antiinflammatory effect of Simvastatin in subjects with the Metabol- ic syndrome显示文摘 | DEVARAJ S CHAN E JIALAL I | 2006 | Journal of Clinical Endocrinology & Metabolism2006，91，11： | 1 |
| 7 | A reverse dot-blot method for rapid detection of non-deletion alpha thalassaemia显示文摘 | Chan V Yam I Chen FE | | 0，，： | 1 |
| 8 | Agronomic values of green waste biochar as a soil amendment 显示文摘 | Chan K Y Van Zwieten L Meszaros I | 2007 | Australian Journal of Soil Research2007，45，： | 1 |
| 9 | On the runup of long waves on a plane beach显示文摘 | CHAN I C LIU P L F | 2012 | Journal of Geophysical Research2012，117，8： | 1 |
| 10 | Preferred risk allocation in target cost contracts in con- struction显示文摘 | Joseph H L Chan Daniel W M Chan Patrick T I Lam | 2011 | Facilities2011，29，1314： | 1 |
| 11 | A physical-space version of the stretched-vortex subgrid-stress model for large-eddy simulation显示文摘 | Voelkl T Pullin D I Chan D C | 2000 | Physics of Fluids2000，12，7： | 1 |
| 12 | Plasma treatments of indium tin oxide anodes in carbon tetrafluorinde( CF4 )/oxygen( 02 )to im- prove the performance of organic light-emitting diodes显示文摘 | CHAN I M HONG F C | 2003 | Thin Solid Films2003，444，： | 1 |
| 13 | Causes of deaths in children younger than 5 years in China in 28显示文摘 | Rudan I Chan KY Zhang JS | 2010 | Lancet2010，，375： | 1 |
| 14 | Isolation of NFE2 related factor 2(Nrf2),a NF-E2-like basic leueine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region显示文摘 | Moi P Chan K Asunis I | 1994 | Proc Natl Acad Sci U S A1994，91，21： | 1 |
| 15 | Phylogenetic variation and polymorphism at the toll-like receptor4 locus(TLR4)显示文摘 | Smirnova I Poltorak A Chan E K | 2000 | Genome Biol2000，1，1： | 1 |
| 16 | Cancer stem cells in bladdercancer: a revisited and evolving concept 显示文摘 | Chan KS Volkmer JP Weissman I | 2010 | Curr Opin Urol2010，20，5： | 1 |
| 17 | Isolation of NF-E2-related factor 2 (Nrf2),a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region显示文摘 | Moi P Chan K Asunis I | | 0，，： | 1 |
| 18 | Role of heal stress transcription factor HsfA5 as specific repressor of HsfA4显示文摘 | ganiwal S K Chan K Y Scharf K I) | | 0，，06： | 1 |
| 19 | AgronomicValues of Greenwaste Biochar as a Soil Amendment显示文摘 | CHAN K Y VAN ZWIETEN L MESZAROS I | 2008 | Soil Re-search2008，45，8： | 1 |
| 20 | Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-1ike basic leucine zipper transcriptional activator that binds to the tandem NF-E2/ AP1 repeat of the beta-globin locus control region 显示文摘 | Moi P Chan K Asunis I | 1994 | Proc Natl Acad Sci U S A1994，91，21： | 1 |
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