| 2 | Merging PROTAC and molecular glue for degrading BTK and GSPT1 proteins concurrently显示文摘Dear Editor,Targeted protein degradation(TPD)represents a promising research field that has quickly attracted attention and efforts from both academia and pharmaceutical industry.TPD technology uses small molecules to induce the degradation of target proteins by harnessing the ubiquitin-proteasome system.PROTAC(PROteo-lysis Targeting Chimeras)1-3 and MG(Molecular Glue)4,5 are two major modes of TPD. | Zimo Yang Yonghui Sun Zhihao Ni Celi Yang Yan Tong Yujie Liu Haitao Li Yu Rao | 2021 | Cell Research2021，31，12： | 1 |
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