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| 1 | 螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。 | Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，3： | 7 |
| 2 | Laparoseopic treatment of vesicovaginal fistula显示文摘 | Tobias-Maehado M Mattos PA Castro PR | 2014 | Int Braz J Urol2014，40，3： | 1 |
| 3 | L-DOPA accessibility in culture medium increases melanin expression and virulence of Sporothrix schenckii yeast cells 显示文摘 | Teixeira PA De Castro RA Ferreira FR | 2010 | Med Mycol2010，48，5： | 1 |
| 4 | Evaluation of Land Consolidation Projects(LCPs):A Multidisciplinary Approach显示文摘 | G Van Huylenbroeck J Castro Coelhot PA Pinto | 1996 | Journal of Rural Studies1996，12，3： | 1 |
| 5 | Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate显示文摘 | Castro J Harrington AM Hughes PA | 2013 | Gastroenterology2013，145，6： | 1 |
| 6 | Molecular char- acterization of the putative transcription factor SebA involved in viru- Lence in Aspergillus fumigatus 显示文摘 | Dinamarco TM Almeida RS de Castro PA | 2012 | Eukaryot Cell2012，11，4： | 1 |
| 7 | Analysis of factors that may influence range of motion after cervical disc arthroplasty 显示文摘 | Kim SW Paik SH Castro PA | 2010 | Spine J2010，10，8： | 1 |
| 8 | Analysis of factors that may influence range of motion after cervical disc arthroplasty 显示文摘 | Kim SW Paik SH Castro PA | 2010 | Spine J2010，10，8： | 1 |
| 9 | polpisoprenylated benzophenone from Cuban propolis显示文摘 | Rubio OC Cuellar AC Rojas N Castro HV Rastrelli L Aquino PA | 1999 | Joumal of Natural Products1999，62，7： | 1 |
| 10 | Molecular characteriza- tion of propolis-induced cell death in Saccharomyces cerevisiae显示文摘 | de Castro PA Savoldi M Bonatto D | 2011 | Eukaryot Cell2011，10，3： | 1 |
| 11 | Hippocampal dysplasia in rats exposed to cocaine in utero显示文摘 | Wenzel H J Castro PA | 1999 | rain Res Dev Brain Res1999，117，2： | 1 |
| 12 | Carotid-basilar artery communication in gerbils (Merionesunguiculatus) 显示文摘 | Castro PA Foyo-Niembro E | 2001 | Rev Neurol2001，32，3： | 1 |
| 13 | Is it time to replace the tuberculin skin test with a blood test显示文摘 | LoBue PA Castro KG | | 0，，03： | 1 |
| 14 | Transcriptional profil- ing of Saecharomyces eerevisiae exposed to propolis显示文摘 | De Castro PA Savoldi M Bonatto D | 2012 | BMC Complement Altern Med2012，12，： | 1 |
| 15 | A large-scale mutagene- sis screen to identify seizure-resistant zebra/ish 显示文摘 | Baraban SC Dinday MT Castro PA | 2007 | Epilepsia2007，48，6： | 1 |
| 16 | Sensory neuroimmune interactions differ between irritable bowel syndrome subtypes显示文摘 | Hughes PA Harrington AM Castro J | 2013 | Gut2013，62，10： | 1 |
| 17 | Analysis of factors that may influence range of motion after cervical disc arthroplasty显示文摘 | Kim SW Paik SH Castro PA | 2010 | Spine J2010，10，8： | 1 |
| 18 | L-DOPA accessibility in etlhure medium increases melanin expression and virulence of Spomthrix sehenekii yeas! cells显示文摘 | Teixeira PA De Castro RA Feneira FI/ el al | 2010 | Med M yeol2010，48，5： | 1 |
| 19 | Nonsteroidal anti-inflammatory drug effectivity in preventing postendoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis显示文摘BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is the primary therapeutic procedure for the treatment of diseases affecting the biliary tree and pancreatic duct.Although the therapeutic success rate of ERCP is high,the procedure can cause complications,such as acute pancreatitis[post-ERCP pancreatitis(PEP)],bleeding and perforation.AIM To assess the efficacy of non-steroidal anti-inflammatory drugs(NSAIDs)in preventing PEP during follow-up.METHODS Databases such as MEDLINE,EMBASE and Cochrane Central Library were searched.Only randomized controlled trials(RCTs)comparing the efficacy of NSAIDs and placebo for the prevention of PEP were included.Outcomes evaluated included the incidence of PEP,severity of pancreatitis,route of administration,types,dose,and timing of administration of NSAIDs.RESULTS Twenty-six RCTs were considered eligible with a total of 8143 patients analyzed.Overall,4020 patients used NSAIDs before ERCP and 4123 did not use NSAIDs(control group).Ultimately,298 cases of post-ERCP acute pancreatitis were diagnosed in the NSAID group and 484 cases in the placebo group.The risk of PEP was lower in the NSAID group risk difference(RD):-0.04;95%confidence interval(CI):-0.07 to-0.03;number needed to treat(NNT),25;P<0.05.NSAID use effectively prevented mild pancreatitis compared to placebo use(2.5%vs 4.1%;95%CI:-0.05 to-0.01;NNT,33;P<0.05),but information on moderate PEP and severe PEP could not be fully elucidated.Only rectal administration reduced the incidence of PEP with RD:-0.06;95%CI:-0.08 to-0.04;NNT,17;P<0.05).Furthermore,only the use of diclofenac or indomethacin was effective in preventing PEP,at a dose of 100 mg,which must be administered before performing ERCP.CONCLUSION Rectal administration of diclofenac and indomethacin significantly reduced the risk of developing mild PEP.Additional RCTs are needed to compare the efficacy between NSAID routes of administration in preventing PEP. | Juan Pablo Román Serrano JoséJukemura Samuel Galante Romanini Paúl Fernando Guamán Aguilar Juliana Silveira Lima de Castro Isabela Trindade Torres JoséAndres Sanchez Pulla Otavio Micelli Neto Eloy Taglieri JoséCelso Ardengh | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，11： | 1 |
| 20 | New oxidized ent-kaurane and ent-norkaurane derivatives from kaurenoic acid显示文摘 | BATISTA R GARC(I)A PA CASTRO MA | 2007 | Journal of the Brazilian Chemical Society2007，18，3： | 1 |
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