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| 1 | Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders: Results from a large Swiss epidemiological study显示文摘AIM To examine the associations between mental disorders and infectious, atopic, inflammatory diseases while adjusting for other risk factors.METHODS We used data from PsyC oL aus, a large Swiss Population Cohort Study(n = 3720; age range 35-66). Lifetime diagnoses of mental disorders were grouped into the following categories: Neurodevelopmental, anxiety(early and late onset), mood and substance disorders. They were regressed on infectious, atopic and other inflammatory diseases adjusting for sex, educational level, familial aggregation, childhood adversities and traumatic experiences in childhood. A multivariate logistic regression was applied to each group of disorders. In a complementary analysis interactions with sex were introduced via nested effects. RESULTS Associations with infectious, atopic and other chronic inflammatory diseases were observable together with consistent effects of childhood adversities and familial aggregation, and less consistent effects of trauma in each group of mental disorders. Streptococcal infections were associated with neurodevelopmental disorders(men), and measles/mumps/rubella-infections with early and late anxiety disorders(women). Gastric inflammatory diseases took effect in mood disorders(both sexes) and in early disorders(men). Similarly, irritable bowel syndrome was prominent in a sex-specific way in mood disorders in women, and, moreover, was associated with early and late anxiety disorders. Atopic diseases were associated with late anxiety disorders. Acne(associations with mood disorders in men) and psoriasis(associations with early anxiety disorders in men and mood disorders in women) contributed sex-specific results. Urinary tract infections were associated with mood disorders and, in addition, in a sex-specific way with late anxiety disorders(men), and neurodevelopmental and early anxiety disorders(women).CONCLUSION Infectious, atopic and inflammatory diseases areimportant risk factors for all groups of mental disorders. The sexual dimorphism of the associations is pronounced. | Vladeta Ajdacic-Gross Aleksandra Aleksandrowicz Stephanie Rodgers Margot Mutsch Anja Tesic Mario Müller Wolfram Kawohl Wulf R?ssler Erich Seifritz Enrique Castelao Marie-Pierre F Strippoli Caroline Vandeleur Roland von K?nel Rosa Paolicelli Markus A Landolt Cornelia Witthauer Roselind Lieb Martin Preisig | 2016 | World Journal of Psychiatry2016,6,4: | 2 |
| 2 | Use of permanent hair dyes and bladder-cancer risk 显示文摘 | GAGO-DOMINGUEZ M CASTELAO JE YUAN JM | 2001 | Int J Cancer2001,91,4: | 1 |
| 3 | FNDC5/irisin is not only a myokine but also an adipokine 显示文摘 | Roca-Rivada A Castelao C Senin LL | 2013 | PLoS One2013,8,60: | 1 |
| 4 | Links influence of diltiazem on cyclosporin clearance显示文摘 | Grino JM Sabate I Castelao AM | 1986 | Lancet1986,1,: | 1 |
| 5 | Lung cancer and cyclooxygenase-2: review article显示文摘 | Castelao JE Bart RD Ⅲ DiPerna CA | 2003 | Ann Thorac Surg2003,76,4: | 1 |
| 6 | Lung cancer and cyclooxygenase-2显示文摘 | J.Esteban Castelao Robert D Bart Costanzo A DiPerna Eric M Sievers Ross M Bremner | 2003 | The Annals of Thoracic Surgery2003,,4: | 1 |
| 7 | Advances in diabetes mellitus, diabetic ne- phropathy, metabolicsyndrome and cardio -- vascular -- renal risk显示文摘 | Martinez Castelao A | 2008 | Nefrologia2008,285,: | 1 |
| 8 | Marine n-3 fatty acid intake,glutathione S-transferase polymorphisms and breast cancer risk in post-menopausal Chinese women in Singapore显示文摘 | Manuela Gago-Dominguez J Esteban Castelao | 2004 | Carcinogenesis2004,25,: | 1 |
| 9 | Advances in diabetes mellitus,diabetic nephropathy,metabolic syndrome and cardio-vascular-renal risk显示文摘 | Martinez Castelao A | 2012 | Nephrologie2012,8,5: | 1 |
| 10 | Lung cancer and cyclooxy- genase -2显示文摘 | Castelao JE Bart RD DiPema CA | 2003 | Ann Thoracic Surg2003,76,4: | 1 |
| 11 | Doxazosin GITS trough to peak ratio and 24-hour blood pressure monitoring in the management of hypertension in renal transplant patients 显示文摘 | Martinez Castelao A Ibernon M Sarrias X | 2003 | Transplant Proc2003,35,: | 1 |
| 12 | 查看详情显示文摘 | Gago D M Castelao J E Yuan J M Yu M C Ross R K | | 0,,: | 1 |
| 13 | Links influence of diltiazem on cyclosporin clearance显示文摘 | Grino JM Sabate I Castelao AM | 1986 | Lancet1986,1,: | 1 |
| 14 | Use of Permanent Hair Dycs and Bladder Cancer Risk显示文摘 | GAGODOMINGUEZ M CASTELAO J E YUAN J M | 2001 | Int J Cancer2001,91,1: | 1 |
| 15 | FNI)CS/ifisin is not only a myokine but also an adipokine 显示文摘 | Roca-Rivada A Castelao C Senin LL | 2013 | PLoS One2013,8,60: | 1 |
| 16 | Treatment of hypertension afterrenal transplantation: Long-term efficacy of verapamil, enalapril,and doxazosin显示文摘 | Castelao AM Hueso M Sanz V | 1998 | Kidney Int1998,54,9: | 1 |
| 17 | Nonsteroidal anti- inflammatory drugs and bladder cancer prevention显示文摘 | CASTELAO J E YUAN J M GAGO DOMINGUEZ M | 2000 | Br-J-Cancer2000,82,7: | 1 |
| 18 | Nonsteroidal anti-inflammatory drugs and bladder cancer prevention显示文摘 | CASTELAO JE YUAN JM GAGO-DOMINGUEZ M | 2000 | BrJ Cancer2000,82,7: | 1 |
| 19 | FNDC5/irisin is not only a myokine but also an adipokine 显示文摘 | Roca-Rivada A Castelao C Senin LL | 2013 | PLoS One2013,,60: | 1 |
| 20 | Phenobarbital use and bladder cancer risk显示文摘 | Castelao JE Gago-Dominguez M Yuan JM | 2003 | Eur J Epidemiol2003,18,7: | 1 |