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| 1 | Augmented reality assisted surgery: a urologic training tool显示文摘扩充现实广泛地在航空学被使用并且是在外科以内的一个发展中的概念。在这个预研项目,我们在古格尔·格拉斯 ® 上为使用开发了一个应用程序训练在怎么放可膨胀的阴茎修复术的泌尿学居民的光装头的显示。我们使用扩充的短语现实帮助了外科在外科的设置描述扩充现实的这个新奇应用程序。应用程序表明可膨胀的阴茎修复术放置的外科的过程的步。它也包含允许的软件用一个照相机的点从光装头的显示喂使教师能在阴茎修复术的放置期间与居民一起交往的兴趣的察觉。自愿参加学习的泌尿学受训练者和教师被给时间经历技术在起作用或 perioperative 背景并且要求完成反馈调查。从用 10 点规模的 30 个全部的参加者,教育实用性被评估 8.6,航行的容易被评估 7.6,到使用的可能性的被评估 7.4,并且在操作空间的分心被评估 4.9。当在受训练者和教师之间成层时,受训练者发现技术更教育有用,并且少些分散。总的来说, 81% 参加者在他们的住处程序想要这种技术,并且 93% 以后在操作房间里看见这种技术。这种技术的进一步的开发在完整的版本前被保证,并且进一步的研究是必要的更好描绘扩充现实的有效性在泌尿科的外科的训练的帮助外科。 | Ryan M Dickey Neel Srikishen Larry I Lipshultz Philippe E Spiess Rafael E Carrion Tariq S Hakky | 2016 | Asian Journal of Andrology2016，18，5： | 6 |
| 2 | Patient satisfaction and penile morphology changes with postoperative penile rehabilitation 2 years after Coloplast Titan prosthesis显示文摘在可膨胀的阴茎修复术外科以后的普通抱怨被减少阴茎长度。我们以前报导了用有好攻击的新长度测量的 Coloplast 泰坦可膨胀的阴茎修复术,技术(NLMT ) 怎么结合了 implant 的手术后的 IPP 康复为 1 年帮助改进耐心的满足和可勃起的阴茎大小。这是 2 年后续一未来,三中心,经历了泰坦修复术放置的 40 个病人的学习,与为可勃起的机能障碍的新长度测量技术。耐心的指令是每天使膨胀 6 个月然后每天为 1-2 h 最大地使膨胀 6-24 月。十五阴茎大小以前并且立即在外科以后并且在后续访问被拿。测量变化作为与相比在 24 个月被改进立即手术后并且在 12 个月。67.8% 题目在 2 年对他们的长度满意,并且 77% 作为在外科以前察觉了更长的阴茎长度(30.8%) 或一样(46.2%) 。64.3% 题目和 17.9% 增加了并且未改变的满足,分别地与阴茎长度作为与相比在以前阴茎植入外科。几乎,一个题目(96.5%) 对他的全面功能满意植入。这研究与好攻击的柱体缩放,和手术后的阴茎康复通货膨胀用 Coloplast 泰坦建议协议能在 2 年 postimplant 优化耐心的满足和可勃起的阴茎大小。 | Michael B Pryor Rafael Carrion Run Wang Gerard Henry | 2016 | Asian Journal of Andrology2016，18，5： | 5 |
| 3 | Aplastic anemia and severe pancytopenia during treatment with peg-interferon,ribavirin and telaprevir for chronic hepatitis C显示文摘Telaprevir and Boceprevir are the first direct acting antivirals approved for chronic hepatitis C in combination with peg-interferon alfa and ribavirin.Pancytopenia due to myelotoxicity caused by these drugs may occur,but severe hematological abnormalities or aplastic anemia(AA) have not been described.We collected all cases of severe pancytopenia observed during triple therapy with telaprevir in four Spanish centers since approval of the drug in 2011.Among 142 cirrhotic patients receiving treatment,7 cases of severe pancytopenia(5%) were identified and three were consistent with the diagnosis of AA.Mean age was 59 years,five patients had compensated cirrhosis and two patients had severe hepatitis C recurrence after liver transplantation.Severe pancytopenia was diagnosed a median of 10 wk after the initiation of therapy.Three patients had pre-treatment hematological abnormalities related to splenomegaly.In six patients,antiviral treatment was interrupted at the onset of hematological abnormalities.Two patients died due to septic complications and one patient due to acute alveolar hemorrhage.The remaining patients recovered.Severe pancytopenia and especially AA,are not rare during triple therapy with telaprevir in patients with advanced liver disease.Close monitoring is imperative in this setting to promptly detect serious hematological disorders and to prevent further complications. | Sabela Lens Jose L Calleja Ana Campillo Jose A Carrion Teresa Broquetas Christie Perello Juan de la Revilla Zoe Marino Maria-Carlota Londono Jose M Sanchez-Tapias Alvaro Urbano-Ispizua Xavier Forns | 2015 | World Journal of Gastroenterology2015，21，17： | 4 |
| 4 | The IgH 3′ regulatory region super-enhancer does not control IgA class switch recombination in the B1 lineage显示文摘The bone marrow-derived B2 population represents the vast majority of bone marrow,blood,lymph node and splenic B-cells.Mouse B1 B-cells mostly originate during embryonic life in the liver and represent the main B-cell population in the pleural and peritoneal cavities.1,2,3,4,5 B1 and B2 B-cells differ in their origin,antigen specificity,cell surface markers,tissue distribution and capacity for class switch recombination(CSR).Schematically,B1 B-cells appear earlier than B2 B-cells during fetal development and maintain their self-renewal ability throughout their life. | Hussein Issaoui Nour Ghazzaui Alexis Saintamand Claire Carrion Christelle Oblet Yves Denizot | 2018 | Cellular & Molecular Immunology2018，15，3： | 4 |
| 5 | Hepatitis B surface antigen and hepatitis B core-related antigen kinetics after adding pegylated-interferon to nucleos(t)ids analogues in hepatitis B e antigen-negative patients显示文摘BACKGROUND Hepatitis B e antigen-negative chronic hepatitis B patients under nucleos(t)ids analogues(NAs)rarely achieve hepatitis B surface antigen(HBsAg)loss.AIM To evaluate if the addition of pegylated interferon(Peg-IFN)could decrease HBsAg and hepatitis B core-related antigen(HBcrAg)levels and increase HBsAg loss rate in patients under NAs therapy.METHODS Prospective,non-randomized,open-label trial evaluating the combination of Peg-IFN 180μg/week plus NAs during forty-eight weeks vs NAs in monotherapy.Hepatitis B e antigen-negative non-cirrhotic chronic hepatitis B patients of a tertiary hospital,under NAs therapy for at least 2 years and with undetectable viral load,were eligible.Patients with hepatitis C virus,hepatitis D virus or human immunodeficiency virus co-infection and liver transplanted patients were excluded.HBsAg and HBcrAg levels(log10 U/mL)were measured at baseline and during ninety-six weeks.HBsAg loss rate was evaluated in both groups.Adverse events were recorded in both groups.The kinetic of HBsAg for each treatment group was evaluated from baseline to weeks 24 and 48 by the slope of the HBsAg decline(log10 IU/mL/week)using a linear regression model.RESULTS Sixty-five patients were enrolled,61%receiving tenofovir and 33%entecavir.Thirty-six(55%)were included in Peg-IFN-NA group and 29(44%)in NA group.After matching by age and treatment duration,baseline HBsAg levels were comparable between groups(3.1 vs 3.2)(P=0.25).HBsAg levels at weeks 24,48 and 96 declined in Peg-IFN-NA group(-0.26,-0.40 and-0.44)and remained stable in NA group(-0.10,-0.10 and-0.10)(P<0.05).The slope of HBsAg decline in Peg-IFN-NA group(-0.02)was higher than in NA group(-0.00)(P=0.015).HBcrAg levels did not change.Eight(22%)patients discontinued Peg-IFN due to adverse events.The HBsAg loss was achieved in 3(8.3%)patients of the Peg-IFN-NA group and 0(0%)of the NA group.CONCLUSION The addition of Peg-IFN to NAs caused a greater and faster decrease of HBsAg levels compared to NA therapy.Side effects of Peg-IFN can limit its use in clinical practice. | Teresa Broquetas Montserrat Garcia-Retortillo Miquel Mico Lidia Canillas Marc Puigvehi Nuria Canete Susana Coll Ana Viu Juan Jose Hernandez Xavier Bessa JoseA Carrion | 2020 | World Journal of Hepatology2020，12，11： | 2 |
| 6 | Loss of Aβ-nerve endings associated with the Merkel cell-neurite complex in the lesional oral mucosa epithelium of lichen planus and hyperkeratosis显示文摘The Merkel cell-neurite complex initiates the perception of touch and mediates Ab slowly adapting type I responses.Lichen planus is a chronic inflammatory autoimmune disease with T-cell-mediated inflammation,whereas hyperkeratosis is characterized with or without epithelial dysplasia in the oral mucosa.To determine the effects of lichen planus and hyperkeratosis on the Merkel cell-neurite complex,healthy oral mucosal epithelium and lesional oral mucosal epithelium of lichen planus and hyperkeratosis patients were stained by immunohistochemistry(the avidin-biotin-peroxidase complex and double immunofluorescence methods)using pan cytokeratin,20(K20,a Merkel cell marker),and neurofilament 200(NF200,a myelinated Ab-and Ad-nerve fibre marker)antibodies.NF200-immunoreactive(ir)nerve fibres in healthy tissues and in the lesional oral mucosa epithelium of lichen planus and hyperkeratosis were counted and statistically analysed.In the healthy oral mucosa,K20-positive Merkel cells with and without close association to the intraepithelial NF200-ir nerve fibres were detected.In the lesional oral mucosa of lichen planus and hyperkeratosis patients,extremely rare NF200-ir nerve fibres were detected only in the lamina propria.Compared with healthy tissues,lichen planus and hyperkeratosis tissues had significantly decreased numbers of NF200-ir nerve fibres in the oral mucosal epithelium.Lichen planus and hyperkeratosis were associated with the absence of Ab-nerve endings in the oral mucosal epithelium.Thus,we conclude that mechanosensation mediated by the Merkel cell-neurite complex in the oral mucosal epithelium is impaired in lichen planus and hyperkeratosis. | Daniela Calderon Carrion Yiiksel Korkmaz Britta Cho Marion Kopp Wilhelm Bloch Klaus Addicks Wilhelm Niedermeier | 2016 | International Journal of Oral Science2016，8，1： | 2 |
| 7 | Ventral phalloplasty显示文摘瞄准:为了在阴茎修复术培植期间介绍一种简单技术,那支持增加的阴茎长度的感觉。方法:阴茎阴囊网被定义。“切口与阴囊的组织的切除被做的一个检查标记”。优秀暴露被为柱体,泵和水库的培植提供。创伤闭合是执行的纵。结果:这种技术是为 webbed 在小儿科的文学描述的手术的修改延期。跟随阴茎培植外科的阴茎长度的损失为受不了可勃起的机能障碍(编辑) 的病人是使人烦恼的的。这种技术帮助做好耐心的满足,化妆品结果,并且改进阴茎长度的感觉。结论:腹的阴茎成形术是可以独自与阴茎修复术培植或作为一个看台在音乐会被执行的一个安全、技术上简单的过程在某些情形下面的过程。 | Jorge Caso Michael Keating Alejandro Miranda-Sousa Rafael Carrion | 2008 | Asian Journal of Andrology2008，10，1： | 2 |
| 8 | Vaccination with a plasmid DNA cocktail encoding the nucleosomal histones of Leishmania confers protection against murine cutaneous leishmaniosis显示文摘 | Iborra S Soto M Carrion J | 2004 | Vaccine2004，22，2930： | 1 |
| 9 | Retroeaval ureter report of 8 eases and the surgical management显示文摘 | Carrion H Howard MT Bredt DS | 1979 | J Urol1979，121，： | 1 |
| 10 | Penile prosthesis: new implant for management of impotence 显示文摘 | Carrion HM | 1975 | J Fla Med Assoc1975，62，10： | 1 |
| 11 | A Stochastic Programming Approach to Electric Energy Procuremem for Large Consumers显示文摘 | Carrion M Philpot A B Conejo A J | 2007 | IEEE Trans on Power Systems2007，22，2： | 1 |
| 12 | Combined penile placation surgery and insertion of penile prosthesis for severe penile curvature and erectile dysfunction显示文摘 | Rahman N U Carrion R E Bochinski D | 2004 | J Urol2004，171，： | 1 |
| 13 | A computationally efficient mixed-integer linear formulation for the thermal unit commitment problem显示文摘 | Carrion M Arroyo J M | 2006 | IEEE Transactions on Power Systems2006，21，3： | 1 |
| 14 | Prenatal diagnosis of interrupted inferior vena eava显示文摘 | Costa P Carrion A Monterroso J | 2007 | Rev Port Cardiot2007，26，5： | 1 |
| 15 | A computationally effi- cient mixed-integer linear formulation for the thermal u- nit commitment problem 显示文摘 | CARRION M ARROYO JM | 2006 | IEEE Transactions on Power Systems2006，21，3： | 1 |
| 16 | Hepatic venous pressure gradient identifies patients at risk of severe hepatitis C recurrence after liver transplantation 显示文摘 | Blasco A Forns X Carrion JA | 2006 | Hepatology2006，43，3： | 1 |
| 17 | Synthesis of SAPO-34 crystals in the presence of crystal growth inhbitors显示文摘 | Venna S R Carrion M A | 2008 | J Phys Chem B2008，12，16： | 1 |
| 18 | Viral hepatitis in the elderly显示文摘 | CARRION A F MARTIN P | 2012 | Am J Gastroenterol2012，107，5： | 1 |
| 19 | Determination of selenium and iodine in human thyroids显示文摘 | Murillo M Carrion N Quintana M | 2005 | J Trace Elem Med Biol2005，19，1： | 1 |
| 20 | Use of plasma urea nitrogen as a rapid response criterion to determine the lysine requirement of pigs 显示文摘 | Coma J Carrion D Zimmerman D R | 1995 | Journal of Animal Science1995，73，2： | 1 |
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