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| 1 | A novel histochemical method for a simultaneous staining of melanin and collagen fibers显示文摘 | Carriel VS Aneiros-Fernandez J Arias-Santiago S | | 0，，： | 1 |
| 2 | Platelet-rich plasma influence on human osteoblasts growth显示文摘 | Ferreira CF Carriel Gomes MC Filho JS | 2005 | Clin Oral Implants Res2005，16，4： | 1 |
| 3 | Platelet-rich plasma influence on human osteoblasts growth显示文摘 | Ferreira CF Carriel Gomes MC Filho JS | | 0，，04： | 1 |
| 4 | Injection of phosphatidylcholine in fat tissue:experimental study of local action in rabbits显示文摘 | Rittes PG Rittes JC Carriel Amary MF | 2006 | Aesthetic Plast Surg2006，30，4： | 1 |
| 5 | Platelet-rich plasma influence on human osteoblasts growth显示文摘 | Ferreira CF Carriel Gomes MC Filho JS | 2005 | Clin Oral Impl Res2005，16，4： | 1 |
| 6 | Injection of phosphatidylcholine in fat tissue:experimental study of local action in rabbits显示文摘 | RITTES J C CARRIEL AMARY M F | 2006 | Aesthetic Plast Surg2006，30，4： | 1 |
| 7 | Platelet- rich plasma influence on human osteoblasts growth 显示文摘 | Ferreira CF Carriel Gomes MC Filho JS | 2005 | Clin Oral Implants Res2005，16，4： | 1 |
| 8 | Dif- ferential expression of GAP-43 and neurofila- ment during peripheral nerve regeneration through bio-artificial conduits 显示文摘 | Carriel V Garzon I Campos A | 2014 | J Tissue Eng Regen Med2014，，10： | 1 |
| 9 | Platelet-rich plasma influence on human osteoblasts growth显示文摘 | Ferreira CF Carriel Gomes MC Filho JS | 2005 | Clin Oral Implants Res2005，16，4： | 1 |
| 10 | Injection of Phosphatidylcholine in Fat Tissue: Experimental Study of Local Action in Rabbits显示文摘 | Patrícia Guedes Rittes M.D. José Carlos Rittes M.D. Maria Fernanda Carriel Amary M.D | 2006 | Aesthetic Plastic Surgery2006，，4： | 1 |
| 11 | Combination of fibrin-agarose hydrogels and adipose-derivedmesenchymal stem cells for peripheral nerve regeneration 显示文摘 | Carriel V Garrido-Gomez J Hemandez-Cortes P | 2013 | JNeural Eng2013，10，02： | 1 |
| 12 | Combination of fibrin-agarose hydrogels and adipose-derivedmesenchymal stem cells for peripheral nerveregeneration 显示文摘 | Carriel V Garrido-Gomez J Hemandez-Cortes P | 2013 | JNeural Eng2013，10，02： | 1 |
| 13 | Injection of phosphatidylcholine in fat tissue:experimental study of local action in rabbits显示文摘 | RITTES P G RITTES J C CARRIEL AMARY M F | 2006 | Aesthetic Plast Surg2006，30，4： | 1 |
| 14 | Platelet-rich plasma influence on human osteoblasts growth显示文摘 | Ferreira CF Carriel Comes MC Filho JS | 2005 | Clin Oral Implants Res2005，16，4： | 1 |
| 15 | Histological assessment in peripheral nerve tissue engineering显示文摘The histological analysis of peripheral nerve regeneration is one of the most used methods to demonstrate the success of the regeneration through nerve conduits. Nowadays, it is possible to evaluate different parameters of nerve regeneration by using histological, histochemical, immunohistochemical and ultrastructural techniques. The histochemical methods are very sensible and are useful tools to evaluate the extracellular matrix remodeling and the myelin sheath, but they are poorly specific. In contrast, the immunohistochemical methods are highly specific and are frequently used for the identification of the regenerated axons, Schwann cells and proteins associated to nerve regeneration or neural linage. The ultrastructural techniques offer the possibility to perform a high resolution morphological and quantitative analysis of the nerve regeneration. However, the use of a single histological method may not be enough to assess the degree of regeneration, and the combination of different histological techniques could be necessary. | Víctor Carriel Ingrid Garzón Miguel Alaminos Maria Cornelissen | 2014 | Neural Regeneration Research2014，9，18： | 1 |
| 16 | Combination of fibrin-agarose hydrogels and adipose-derived mesenchymal stem cells for peripheral nerve regeneration显示文摘 | Víctor Carriel Juan Garrido-Gómez Pedro Hernández-Cortés Ingrid Garzón Salomé García-García José Antonio Sáez-Moreno María del Carmen Sánchez-Quevedo Antonio Campos Miguel Alaminos | 2013 | Journal of Neural Engineering2013，，2： | 1 |
| 17 | Peripheral nerve regeneration through nerve conduits evokes differential expression of growth-associated protein-43 in the spinal cord显示文摘Growth-associated protein 43 plays a key role in neurite outgrowth through cytoskeleton remodeling.We have previously demonstrated that structural damage of peripheral nerves induces growth-associated protein 43 upregulation to promote growth cone formation.Conversely,the limited regenerative capacity of the central nervous system due to an inhibitory environment prevents major changes in neurite outgrowth and should be presumably associated with low levels of growth-associated protein 43 expression.However,central alterations due to peripheral nerve damage have never been assessed using the growthassociated protein 43 marker.In this study,we used the tubulization technique to repair 1 cm-long nerve gaps in the rat nerve injury/repair model and detected growth-associated protein 43 expression in the peripheral and central nervous systems.First,histological analysis of the regeneration process confirmed an active regeneration process of the nerve gaps through the conduit from 10 days onwards.The growth-associated protein 43 expression profile varied across regions and follow-up times,from a localized expression to an abundant and consistent expression throughout the regeneration tissue,confirming the presence of an active nerve regeneration process.Second,spinal cord changes were also histologically assessed,and no apparent changes in the structural and cellular organization were observed using routine staining methods.Surprisingly,remarkable differences and local changes appeared in growth-associated protein 43 expression at the spinal cord level,in particular at 20 days post-repair and beyond.Growth-associated protein 43 protein was first localized in the gracile fasciculus and was homogeneously distributed in the left posterior cord.These findings differed from the growth-associated protein 43 pattern observed in the healthy control,which did not express growth-associated protein 43 at these levels.Our results revealed a differential expression in growth-associated protein 43 protein not only in the regenerating nerve tissue but also in the spinal cord after peripheral nerve transection.These findings open the possibility of using this marker to monitor changes in the central nervous system after peripheral nerve injury. | Jesús Chato-Astrain Olga Roda David Sánchez-Porras Esther Miralles Miguel Alaminos Fernando Campos Óscar Darío García-García Víctor Carriel | 2023 | Neural Regeneration Research2023，18，8： | 0 |
| 18 | Chitosan conduits enriched with fibrin-collagen hydrogel with or without adipose-derived mesenchymal stem cells for the repair of 15-mm-long sciatic nerve defect显示文摘Hollow conduits of natural or synthetic origins have shown acceptable regeneration results in short nerve gap repair;however,results are still not comparable with the current gold standard technique“autografts”.Hollow conduits do not provide a successful regeneration outcome when it comes to critical nerve gap repair.Enriching the lumen of conduits with different extracellular materials and cells could provide a better biomimicry of the natural nerve regenerating environment and is expected to ameliorate the conduit performance.In this study,we evaluated nerve regeneration in vivo using hollow chitosan conduits or conduits enriched with fibrin-collagen hydrogels alone or with the further addition of adipose-derived mesenchymal stem cells in a 15 mm rat sciatic nerve transection model.Unexpected changes in the hydrogel consistency and structural stability in vivo led to a failure of nerve regeneration after 15 weeks.Nevertheless,the molecular assessment in the early regeneration phase(7,14,and 28 days)has shown an upregulation of useful regenerative genes in hydrogel enriched conduits compared with the hollow ones.Hydrogels composed of fibrin-collagen were able to upregulate the expression of soluble NRG1,a growth factor that plays an important role in Schwann cell transdifferentiation.The further enrichment with adipose-derived mesenchymal stem cells has led to the upregulation of other important genes such as ErbB2,VEGF-A,BDNF,c-Jun,and ATF3. | Marwa El Soury óscar Darío García-García Isabella Tarulli Jesús Chato-Astrain Isabelle Perroteau Stefano Geuna Stefania Raimondo Giovanna Gambarotia Víctor Carriel | 2023 | Neural Regeneration Research2023，18，6： | 0 |
| 19 | Myelin histology:a key tool in nervous system research显示文摘The myelin sheath is a lipoprotein-rich,multilayered structure capable of increasing conduction velocity in central and peripheral myelinated nerve fibers.Due to the complex structure and composition of myelin,various histological techniques have been developed over the centuries to evaluate myelin under normal,pathological or experimental conditions.Today,methods to assess myelin integrity or content are key tools in both clinical diagnosis and neuroscience research.In this review,we provide an updated summary of the composition and structure of the myelin sheath and discuss some histological procedures,from tissue fixation and processing techniques to the most used and practical myelin histological staining methods.Considering the lipoprotein nature of myelin,the main features and technical details of the different available methods that can be used to evaluate the lipid or protein components of myelin are described,as well as the precise ultrastructural techniques. | Óscar Darío García-García Víctor Carriel Jesús Chato-Astrain | 2024 | Neural Regeneration Research2024，19，2： | 0 |
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