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197篇 您的检索式:作者名="Carr I"
    题名 作者 年代 出处 被引量
1多途径丝裂原激活的蛋白激酶介导一氧化氮引起的肝癌细胞凋亡显示文摘目的 研究非离子型的diazeniumdiolate类一氧化氮供体引起肝癌细胞凋亡的分子机制。方法 利用免疫印迹、免疫沉淀、凝胶阻滞实验研究一氧化氮供体处理Hep3B肝癌细胞后,丝裂原激活的蛋白激酶、AP-1的激活以及和Hep3B肝癌细胞凋亡的关系。结果 一氧化氮可引起细胞外信号调节蛋白激酶、c-jun N末端激酶和p38激酶的激活,特别是细胞外信号调节的蛋白激酶的持续激活,其中细胞外信号调节的蛋白激酶和c-jun N末端激酶的特异的阻断剂U0126和JNK抑制剂Ⅱ可阻断AP-1的激活和Hep3B细胞的凋亡,而p38激酶的阻断剂SB203580不能阻断AP-1的激活和Hep3B肝癌细胞的凋亡。结论 一氧化氮通过激活细胞外信号调节蛋白激酶、c-jun N末端激酶,进而激活AP-1而引起Hep3B肝癌细胞的凋亡。任正刚 刘银坤 Ziqiu Wang Sid Kar Brian I Carr 2004肿瘤2004,24,5:3
2Angiotensin receptor blockers improve survival outcomes after radiofrequency ablation in hepatocarcinoma patients显示文摘Antonio Facciorusso Valentina Del Prete Nicola Crucinio Nicola Muscatiello Brian I Carr Alfredo Di Leo Michele Barone 2015J Gastroenterol Hepatol2015,,11:2
3Computed tomographic assessment of fractures of the posterior wall of the acetabulum after operative treatment显示文摘Moed B R Willson Carr S E Gruson K I 2007J Bone Joint Surg Am2007,85,3:1
4Liver transplantation and chemotherapy for hepatoblastoma and hepatocellu- lar cancer in childhood and adolescence显示文摘Reyes J D Carr B Dvorchik I 2000J Pediatr2000,136,:1
5Sensitivity analysis for structural errors 显示文摘NOWAK A S CARR R I 1985Journal of the structural engineering1985,,8:1
6Salicylic acid, a likely endogenous signal in the resistance response of tobacco to viral infection显示文摘Malamy J Carr J P Klessig D F Raskin I 1990Science1990,,250:1
7Reaction of ketene with atomic hydrogen and oxygen 显示文摘Carr R W Jr Gay I D 1968J Chem Phys1968,49,2:1
8Clinical evaluation of lens culi-naris agglutinin-reactive alpha-fetoprotein and des-gamma-carboxyprothrombin in histologically proven hepatocellular carcinoma in theUnited States显示文摘Carr B I Kanke F Wise M 2007Dig Dis Sci2007,52,3:1
9Computed tomographic assessment of fractures of the posterior wall of the aeetabulum after operative treatment 显示文摘Moed B R Willson Carr S E Gruson K I 2003J Bone Joint Surg Am2003,85,3:1
10Cost, schedule and time variances and integration 显示文摘Carr Robert I 1993Journal of Construction Engineering and Management1993,,6:1
11A simple prognostic scoring system for patients with unresectable hepatocellular carcinoma treated by chemo-embolization显示文摘Dvorchik I Carr BI 2007Cancer Detect Prev2007,31,2:1
12Drug delivery from a liquidcrystalline base across visking and human stratum comeum显示文摘CARR M G CORISH J CORRIGAN O I 0,,01:1
13Chemoreception in the pigfish, Orthopristis chrysopterus : the contribution of amino acids and beta- ine to stimulation of feeding behavior by various ex- tracts 显示文摘CARR W E S BLUMENTHAL K M NETHERTON J C l]I 1977Comparative Biochemistry and Physiology1977,58,1:1
14A complete screening of the IL4 gene: novel polymorphisms and their association with asthma and IgE in childhood 显示文摘Kabesch M Tzotcheva I Carr D 2003J Allergy Clin Immunol2003,112,5:1
15Detection of liver cells in peripheral blood of patients with advanced-stage hepatocellular carcinoma 显示文摘Kar S Carr B I 1995Hepatology1995,21,2:1
16Asynthesis of currentunderstanding of the structural evolution of North Africa显示文摘Badalini G Redfern J Carr I D 2002Journal of Petroleum Geology2002,25,3:1
17Safety and efficacy of 90 Y radiotheraphy for hepatocellular carcinoma with and without por- tal vein thrombosis显示文摘Kulik L M Carr B I Malcahy M F 2008Hepatology2008,47,1:1
18Development of an outpatient GFR procedure suitable for epidemioLogical investi- gations 显示文摘D' Mello L Niculescu I Carr E 2001J Am Soc Nephrol2001,,:1
19Stable isotopes and sclerochronology of the bivalve Mesodesma donacium: Potential application to Peruvian paleoceanographic reconstructions显示文摘Carr M Bentaleb I Blamart D 2005Palaeogeography Palaeoclimatology Palaeoecology2005,228,:1
20Second-order sequence stratigraphy of the Pa-laeozoic of North Africa显示文摘Carr I D 2002Journal of Petroleum Geolo-gy2002,25,3:1
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