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| 1 | Fertility preservation in female cancer patients:a single center experience显示文摘Advances in cancer treatment allow women to be cured and live longer. However, the necessary chemotherapy and radiotherapy regimens have a negative impact on future fertility. Oncofertility has emerged as a new interdisciplinary field to address the issue of gonadotoxicity associated with cancer treatment and to facilitate fertility preservation, including oocyte and ovarian tissue cryopreservation. These fertility issues are often inadequately addressed, and referral rates to oncofertility centers are low. The aim of this study was to report the 3-year experience of the San Raffaele Oncofertility Unit. A total of 96 patients were referred to the Oncofertility Unit for evaluation after the diagnosis of cancer and before gonadotoxic treatment between April 2011 and June 2014. Of the 96 patients, 30(31.2%) were affected by breast cancers, 20(20.8%) by sarcomas, 28(29.2%) by hematologic malignancies, 13(13.5%) by central nervous system cancers, 3(3.1%) by bowel tumors, 1(1.0%) by Wilms' tumor, and 1(1.0%) by a thyroid tumor; 47(49.0%) were referred for oocyte cryopreservation before starting chemotherapy, 20(20.8%) were referred for ovarian tissue cryopreservation, and 29(30.2%) were not recruited. The mean time between the patients' counseling and oocyte retrieval was 15 days(range, 2–37 days). The mean time between the laparoscopic surgery and the beginning of treatment was 4 days(range, 2–10 days). The number of patients who were referred increased over time, whereas the rate of patients who were not recruited decreased, showing an improvement in referrals to the Oncofertility Unit and in the patients' counseling and understanding. Our results indicate that an effective multidisciplinary oncofertility team is necessary for prompt referrals and treatment. | Cristina Sigismondi Enrico Papaleo Paola Viganò Simona Vailati Massimo Candiani Jessica Ottolina Valentina E. Di Mattei Giorgia Mangili | 2015 | Chinese Journal of Cancer2015，34，1： | 7 |
| 2 | Human chorionic go- nadotropin level as a predictor of trophoblastic infiltration into the tubal wall in ectopic pregnancy:a blinded study 显示文摘 | Natale A Candiani M Medo D | 2003 | Fertil steril2003，79，4： | 1 |
| 3 | N-acetylcysteine treatment normalizes serum tumor necrosis factor-alpha level and hinders the progression of cardiac injury in hypertensive rats显示文摘 | Bourraindeloup M Adamy C Candiani G | 2004 | Circulation2004，110，14： | 1 |
| 4 | Human chronic gonadotropin level as a predictor of trophoblastic infiltration into the tubal wall in ectopic pregnancy:a blinded study显示文摘 | Natale A Candiani M Merto D | 2003 | Fertility Sterility2003，79，4： | 1 |
| 5 | Human chorionic gonadotrop in levers as predictor of trophoblastic in filtration to the tubal wall inectopic pregnancy:a blind study显示文摘 | Natale A Candiani M Merlo D | 2003 | Fertil Steril2003，79，： | 1 |
| 6 | Predictive biomarkers of preeclampsia and effectiveness of preventative interventions for the disease 显示文摘 | Inversetti A Smid M Candiani M | 2014 | Expert Opin Bioi Ther2014，14，8： | 1 |
| 7 | Presacral neurectomy for the treatment of pelvic pain associated with endometriosis:A controlled study显示文摘 | Candiani GB Fedele L Vercellini P | 1992 | Am J Obstet Gynecol1992，167，： | 1 |
| 8 | Risk of recurrence after myomectomy显示文摘 | Candiani GB Fedele L Parazzini F | | 0，，04： | 1 |
| 9 | Determinants of longterm clinically detected recurrence rates of deep,ovarian,and pelvic endometriosis显示文摘 | Busacca M Chiaffarino F Candiani M | 2006 | Am J Obstet Gynecol2006，195，2： | 1 |
| 10 | Laparoscopic sacrocolpopexy in the treatment of vaginal vault prolapse : 8 years experience 显示文摘 | Granese R Candiani M Perino A | 2009 | Eur J Obstet Gyneeol Reprod Biol2009，146，2： | 1 |
| 11 | Bioreducible liposomes for gene delivery: from the formulation to the mechanism of action 显示文摘 | Candiani G Pezzoli D Ciani L | 2010 | PLoS One2010，5，13： | 1 |
| 12 | The use of thallium201 in the preoperative detection of breast cancer: an adjunct to mammography and ultrasonography显示文摘 | Cimitan M Volpe R Candiani E | 1995 | Eur J Nucl Med1995，22，： | 1 |
| 13 | Anatomical study on the temporal fascial layers and their relationships with the facial nerve显示文摘 | Campiglio GL Candiani P | | 0，，2： | 1 |
| 14 | Human chorionic gonado- tropin level as a predictor of trophoblastic infiltration into the tub- al wall in ectopic pregnancy: a blinded study显示文摘 | Natale A Candiani M Merto D etal | 2003 | Fertil Steril2003，79，4： | 1 |
| 15 | Human ehofionie gonadotropin levels as a predictor of trophoblasttic infiltration into the tubal wall in ectopic pregnancy : a blinded study 显示文摘 | Natale A Candiani M Merlo D | 2003 | Fertil Steril2003，79，： | 1 |
| 16 | Halometasone cream by day and halometasone ointment at night for the treatment of patients with chronic psoriasis vulgaris显示文摘 | Galbiati G Bonfacini V Candiani F | 1983 | J Int Med Res1983，11，1： | 1 |
| 17 | The use of thallium-201 in the preoperative detection of breast cancer:an adjunct to mammography and ultrasonography显示文摘 | Volpe R Candiani E | 1995 | Eur J Nucl Med1995，22，10： | 1 |
| 18 | N-acetylcysteine treatment normalizes serum tumor necrosis factor-alpha level and hinders the progression of cardiac injury in hypertensive rats 显示文摘 | Bourraindeloup M Adamy C Candiani G | 2004 | Circulation2004，110，： | 1 |
| 19 | A loss-based, magnetic field sensor implemented in a ferrofluidinfiltrated microstructured polymer optical fiber 显示文摘 | Candiani A Argyros A Leon-Saval S G | 2014 | -plied Physics Letters2014，104，11： | 1 |
| 20 | Surgical treatment of deep endometriosis and risk of recurrence 显示文摘 | Vignali M Bianchi S Candiani M | 2005 | J Minim Invasive Gynecol2005，12，： | 1 |
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