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| 1 | Caerulin-induced pancreatitis in rats: Histological and genetic expression changes from acute phase to recuperation显示文摘瞄准:为了学习组织学、联系胰腺炎的蛋白质 mRNA 累积,在老鼠从导致 caerulin 的胰腺炎的尖锐阶段胰改变到恢复。方法:尖锐胰腺炎被 caerulein 在男 Wistar 老鼠导致并且列在后面在上面为 90 d 由组织学并且胰的 mRNA 分析。胰在 0 点被把, 9, 24 h 并且 3, 5, 15, 30, 60, 90 d 正式就职以后。浮肿(E) , polymorphonuclear neutrophil (PMN ) 渗入,细胞质的空泡形成(V) ,酶原小粒弄空(ZD ) 和腺泡组织的破坏(广告) 是评估的用显微镜。联系胰腺炎的蛋白质(奶头) 和 L13A mRNAs 的累积被即时 PCR 确定。结果:主要组织学的变化出现在为 PMN 渗入和细胞质的 V 正式就职以后的 9 h 在为 E 和 ZD 的 24 h 和 3 d 分别地。所有参数在 5 d 以后被恢复,除了推迟了超过 30 d 的 ZD。主要广告在 15 d 以后被观察,值在 30 d 以后回到了正常。同样到组织学的变化, PAP mRNA 的累积在 24 h 与最高的累积在 9 h 被增加,差别消失在 5 d 以后。结论:从尖锐阶段发生到胰的胰腺炎,新生和重新区别的恢复并且奶头表示是只胰腺炎的尖锐回答。 | Javier Magaa-Gómez Guillermo López-Cervantes Ana María Calderón de la Barca | 2006 | World Journal of Gastroenterology2006，12，25： | 2 |
| 2 | A comparison of clinical practice guideline appraisal instruments显示文摘 | Graham ID Calder LA Hebert PC | 2000 | Int J Technol Assess Health Care2000，16，4： | 1 |
| 3 | DDT induces apoptosis in human mononuclear cells in vitro and is associated with increased apoptosis in exposed children 显示文摘 | Pérez-Maldonado IN D??az-Barriga F de la Fuente H González-Amaro R Calderón J Yá?ez L | 2004 | Environ Res2004，94，1： | 1 |
| 4 | Gemeprost-induced cervical ripening:histological and biophysical effects 显示文摘 | Geer LA Millar M Calder A | 1992 | Eur J Obstet Gynecol Reprod Biol1992，47，： | 1 |
| 5 | Anti-ulcerogenic and anti-inflammatory activity of the methanolic extract of Larrea divaricata Cav. in rat显示文摘 | Ana María Pedernera Teresita Guardia Carola Guardia Calderón Alejandra Ester Rotelli Nadir Ernesto de la Rocha Silvia Di Genaro Lilian Eugenia Pelzer | 2005 | Journal of Ethnopharmacology2005，，3： | 1 |
| 6 | A comparison of clinical practice guideline appraisal instruments 显示文摘 | Graham ID Calder LA Hebert PC | 2000 | Int J Technol Assess Health Care2000，16，4： | 1 |
| 7 | Prospective validation of a modified thrombolysis in myocardial infarction risk score in emergency de- partment patients with chest pain and possible acute coronary syn- drome显示文摘 | Hess EP3 Perry JJ Calder LA | 2010 | Acad Emerg Med2010，17，4： | 1 |
| 8 | Automatic processing of high-rate,high-density multibeam echosotmder data显示文摘 | Calder BR Mayer LA | 2002 | Geoehem-Geophys-Geosyst2002，4，6： | 1 |
| 9 | Gluten-Free Breads and Cookies of Raw and Popped Amaranth Flours with Attractive Technological and Nutritional Qualities显示文摘 | Ana María Calderón de la Barca María Elvira Rojas-Martínez Alma Rosa Islas-Rubio | 2010 | Plant Foods2010，65，： | 1 |
| 10 | A comparison of clinical practice guideline appraisal instruments显示文摘 | Graham ID Calder LA Hebert PC | 2000 | Int J Technol Assess Health Care2000，16，4： | 1 |
| 11 | Steroid-refractory ulcerative colitis and associated primary sclerosing cholangitis treated with infliximab显示文摘Primary sclerosing cholangitis is an infrequent extraintestinal manifestation of ulcerative colitis.Damage to bile ducts is irreversible and medical therapies to prevent progression of the disease are usually ineffective.We describe a patient with long-standing ulcerative colitis,which was refractory to corticosteroid therapy who developed primary sclerosing cholangitis(biochemical stage Ⅱ/Ⅳ) in the course of his pancolitis.Treatment with infliximab(5 mg/kg as an induction dose followed by maintenance doses every two months) was indicated because of steroid-dependent disease associated to primary sclerosing cholangitis as well as sacroiliitis and uveitis and previous episode of severe azathioprinerelated hepatic toxicity.At present,after two years of follow-up,the patient is asymptomatic with normal liver tests and complete resumption of daily life activities.This case draws attention to the usefulness of antitumor necrosis factor-alpha therapy for the management of primary sclerosing cholangitis as extraintestinal manifestation of inflammatory bowel disease. | Ileana Duca Patricia Ramírez de la Piscina Silvia Estrada Rosario Calderón Katerina Spicakova Leire Urtasun Carlos Marra-López Salvador Zabaleta Raquel Bengoa María Asunción Marcaide Francisco García-Campos | 2013 | World Journal of Gastroenterology2013，19，4： | 1 |
| 12 | A comparison of clinical practice guideline appraisal instruments 显示文摘 | Graham ID Calder LA Hebert PC | 2000 | Int J Technol Assess Health Care2000，16，： | 1 |
| 13 | Vaginal administration of PGE2 for inducing labor stimulates endogenous PGE2 production 显示文摘 | Greer LA Mclaren M Calder AA | 1990 | Acta Obstet Gynecol Scand1990，69，5： | 1 |
| 14 | Prospective validation of a modified thrombolysis in myocardial infarction risk score in emergency department patients with chest pain and possible acute coronary syndrome 显示文摘 | Hess EP Perry JJ Calder LA | 2010 | Acad Emerg Med2010，417，4： | 1 |
| 15 | A Comparison of Clin- ical Practice Guideline Appraisal Instruments 显示文摘 | Graham ID Calder LA Hebert PC | 2000 | Int J Technol Assess Health Care2000，16，4： | 1 |
| 16 | Vaginal administration of PGE2 for inducing labor stimulates endogenous PGE2 production显示文摘 | Greer LA Mclaren M Calder AA | 1990 | Acta Obstet Gynecol Scand1990，69，5： | 1 |
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