维普中文期刊产品整合服务
1543篇 您的检索式:作者名="COOK K"
    题名 作者 年代 出处 被引量
1Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed.Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee 2014World Journal of Clinical Oncology2014,5,2:5
2Tumor necrosis factor-alpha neutralization reduces lung injury after experimental allogeneic bone marrow transplantation显示文摘Cooke K R Hill G R Gerbitz A 2000Transplantation2000,70,2:2
3A critical evaluation of cysteamine as a tool to deplete somatostatin in the rat central nervous system 显示文摘Cook L L Bissette G Dole K 1989Endocrinology1989,124,2:2
4高羊茅干草部分替代玉米和紫花苜蓿青贮饲料对奶牛消化、泌乳性能的影响显示文摘试验旨在研究高羊茅干草替代玉米或紫花苜蓿青贮对奶牛中性洗涤纤维(NDF)消化率、泌乳性能的影响。选取初产哺乳荷斯坦奶牛(产奶75±35 d)24头,经产荷斯坦奶牛(产奶68±19 d)40头,随机分成4组,共设置32个进料闸门,记录采食量。每组8个进料阀门,以1头牛为1个试验单位,每头牛试验过程中可接触8个进料闸门。试验用高羊茅干草(TF)取代玉米青贮饲料(CS)或紫花苜蓿青贮饲料(AS),试验设计为:33%AS和67%CS(空白组)、60%TF和40%AS(试验1组)、60%TF和40%CS(试验2组)、33%TF和67%CS(试验3组)。试验进行7周,前2周进行预饲。试验结果表明,各组间牛奶产量无显著差异,平均值为40.4 kg·d^(-1)。各组间牛奶中脂肪含量和浓度、蛋白质含量和浓度均无显著差异,平均值为1.58 kg·d^(-1)和3.94%、1.28 kg·d^(-1)和3.15%。与试验1组(22.1 kg·d^(-1))、试验3组(22.7 kg·d^(-1))相比,空白组的干物质摄入量最高,为24.5kg·d^(-1)。各组间总的干物质消化率无显著差异,平均值为66.2%。与试验2组(44.4%)、试验3组(45.3%)相比,空白组的NDF消化率较低,为37.8%,与试验1组(42.4%)相近。各组间奶牛体内NDF消化率(42.3%)与预估的NDF消化率(42.6%)相近。试验结果表明,饲喂高羊茅干草可提高饲料中NDF消化率,部分替代玉米和紫花苜蓿时对产奶量无显著影响,在市场价格较低时,可作为经济实用的奶牛饲料。Bender R W Lopes F Cook D E Combs D K 2016饲料博览2016,0,8:2
5Short term evaluation of carbon coated and uncoated porous titanium implants clin显示文摘 COOK S D HADDAD R J 1989Clin Mater1989,4,:1
6Prevention of ventilator associated pneumonia:Current practice in Canadian intensive care units显示文摘Heyland D K Cook D J Dodek P M 2002J Crit Care2002,17,3:1
7The pathogenesis of turkey rhinotracheitis virus in turkey poults inoculate with the virus alone or together with two stains of bacteria显示文摘Cook J K A Ellis M M Huggins M B 1991Avian Pathol1991,20,:1
8A study of 4-substituted 5,5-diaryl oxazolidin-2-ones as efficacious chiral auxiliaries显示文摘Gibson C L Gillon K Cook S 1998Tetrahedron Lett1998,39,:1
9Aromas of rosemary and lavender essential oils differentially affect cognition and mood in healthy adults显示文摘Moss M Cook J wesnes K 0,,01:1
10Effects of T-2 mycotoxin on gastrointestinal tissues : a review of in vivo and in vitro models 显示文摘WORRELL N R MALLETT A K COOK W M 1989Environ Toxicol1989,18,1:1
11Pathotyping of Aus- tralian isolates of Marekg disease virus and association of pathogenicity with meq gene polymorphism 显示文摘Renz K G Cooke J Clarke N 2012Avian Pathol2012,41,2:1
12Jacked piles in London Clay:a study of load transfer and settlement under working conditions 显示文摘Cooke R W Price G Tarr K 1979Geotechnique1979,29,2:1
13The effects of increaseddose of exercise-based therapies to enhance motor recoveryafter stroke: a systematic review and meta-analysis显示文摘Cooke EV Mares K Clark A 2010BMCMed2010,8,:1
14Transient liquid phase diffusion bonding A1-6061 using nano-dispersed Ni coatings 显示文摘COOKE K O KHAN T I OLIVER G D 2011Materials and Design2011,33,:1
15Retarded differential equations with piecewise constant delays显示文摘Cooke K L Wiener J 1984J Math Anal Appl1984,99,:1
16A computer generated stereotactic 'virtual subdural grid' to guide resective epilepsy surgery显示文摘Morris K O'Brien TJ Cook MJ 2004AJNR Am J Neuroradiol2004,25,:1
17Multiplex real-time reverse transcription PCR assay for determination of hepatitis C virus genotypes显示文摘Cook L Sullivan K Krantz E M 2006J Clin Microbiol2006,44,:1
18Analysis of acrolein and acrylonitrile in aqueous solution by membrane introduction mass spectrometry显示文摘Choudhury T K Kotiaho T Cooks R G 1992Talanta1992,39,:1
19Heme oxygenase activity in the adult rat aorta and liver as measures by carbon monoxide for mation显示文摘Cook MN Nakatsu K Marks GS 1995Can J Physiol P harmacol1995,73,4:1
20A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus显示文摘BAYLISS C D PETERS R W COOK J K A 1991Arch Virol1991,120,:1
返回顶部 每页显示:
共78页 首页 上一页 第1页 下一页 末页 /78 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费