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| 1 | Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review显示文摘Human papillomavirus(HPV) has been implicated in the pathogenesis of a subset of oropharyngeal squamous cell carcinoma. As a result, traditional paradigms in relation to the management of head and neck squamous cell carcinoma have been changing. Research into HPVrelated oropharyngeal squamous cell carcinoma is rapidly expanding, however many molecular pathological and clinical aspects of the role of HPV remain uncertain and are the subject of ongoing investigation. A detailed search of the literature pertaining to HPV-related oropharyngeal squamous cell carcinoma was performed and information on the topic was gathered. In this article, we present an extensive review of the current literature on the role of HPV in oropharyngeal squamous cell carcinoma, particularly in relation to epidemiology, risk factors, carcinogenesis, biomarkers and clinicalimplications. HPV has been established as a causative agent in oropharyngeal squamous cell carcinoma and biologically active HPV can act as a prognosticator with better overall survival than HPV-negative tumours. A distinct group of younger patients with limited tobacco and alcohol exposure have emerged as characteristic of this HPV-related subset of squamous cell carcinoma of the head and neck. However, the exact molecular mechanisms of carcinogenesis are not completely understood and further studies are needed to assist development of optimal prevention and treatment modalities. | Robbie SR Woods Esther M O'Regan Susan Kennedy Cara Martin John J O'Leary Conrad Timon | 2014 | World Journal of Clinical Cases2014，2，6： | 5 |
| 2 | Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma eell lines显示文摘 | Mader J S Salsman J Conrad D M | 2005 | Mol Cancer Ther2005，4，4： | 1 |
| 3 | Mechanism of mutagenesis by O6-methylguanine显示文摘 | Eadie JS Conrad M Toorchen D | 1984 | Nature1984，308，5955： | 1 |
| 4 | The nuclear form of phospholipid hydroperoxide glutathione peroxidase is a protein thiol peroxidase contributing to sperm chromatin stability显示文摘 | Conrad M Moreno SG Sinowatz F | 2005 | Mol Cell Biol2005，25，17： | 1 |
| 5 | Separate pathways for cellular uptake of ferric and fer- rous iron显示文摘 | CONRAD M E UMBREIT J N MOORE E G | 2000 | American Journal of Physiology : Gastro- intestinal and Liver Physiology2000，279，： | 1 |
| 6 | Detecting active methanogenic populations on rice roots using stable isotope probing 显示文摘 | Lu Y Lueders T Friedrich M W Conrad R | 2005 | Environ Microbiol2005，7，3： | 1 |
| 7 | Components of short-horizon individual security returns显示文摘 | Conrad J Kaul G Nimalendran M | 1991 | Journal of Financial Economics1991，29，： | 1 |
| 8 | Stabilization of second order evolution equations by unbounded nonlinear feed-back显示文摘 | CONRAD F PIERRE M | 1994 | Ann de 1''I H P analyse non lineaire1994，11，： | 1 |
| 9 | Hyponatremia in intraeranial disorders 显示文摘 | Conrad M J Meinders Aortal J C | 2001 | Net J Med2001，58，3： | 1 |
| 10 | Impact of hypercalcemia and parathyroid hormone level on the sensitivity of preoperative sestamibi scanning for primary hyperparathyroidism显示文摘 | Parikshak M Castillo E D Conrad M F | 2003 | Am Surg2003，69，5： | 1 |
| 11 | Growth disturbances associated with untreated benign bone systs显示文摘 | Clayer M Boatright C Conrad E | 1997 | Aust N Z J Surg1997，67，： | 1 |
| 12 | Neosporosisin cattle显示文摘 | Anderson M L Andrianarivo A G Conrad P A | 2000 | Animal Reproduction Science2000，60，： | 1 |
| 13 | Specific inflammatory cytokines regulate the expression of human monocyte 15-lipexygenase 显示文摘 | Conrad DJ KUhn H Mulkins M | 1992 | Proc Natl Acad Sci U S A1992，89，1： | 1 |
| 14 | The nuclear form of phospholipid hydroperoxide glutathioneperoxidase is a protein thiol peroxidase contributing to sperm chromatin stability显示文摘 | Conrad M Moreno S G Sinowatz F | 2005 | Mol Cell Bio2005，125，： | 1 |
| 15 | Urinary concentration and tissue messenger RNA expression of monocyte chemoattractant protein-1 as an indicator of the degree of hydronephrotic atrophy in partial ureteral obstruction显示文摘 | Stephan M Conrad S Eggert T | | 0，，： | 1 |
| 16 | Athletic footwear,leg stiffness,and running kinematics显示文摘 | Bishop M Fiolkowski P Conrad B Brunt D Horodyski M | | 0，，： | 1 |
| 17 | Effect of electric current pulses on the recrystallization of copper 显示文摘 | Conrad H NASSER K SARDARI M | 1983 | Scripta metallurgica1983，17，3： | 1 |
| 18 | Ethics instruction in the dental hygiene curriculum显示文摘 | KACERIK M G PRAJER R G CONRAD C | 2006 | Dent Hyg2006，80，1： | 1 |
| 19 | Generation of pluripotent stem cells from adult human testis 显示文摘 | CONRAD S RENNINGER M HENNENLOTI'ER J | 2008 | Nature2008，456，7220： | 1 |
| 20 | Heterozygote and mutation detection by direct automated fluorescent DNA sequencing using a mutant Taq DNA polymerase显示文摘 | CHADWICK R B CONRAD M P MCGINNIS M D | 1996 | Biotechniques1996，20，4： | 1 |
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