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| 1 | Complications of diagnostic and therapeutic ERCP: a prospective multicenter study显示文摘 | E Masci G Toti A Mariani S Curioni A Lomazzi M Dinelli G Minoli C Crosta U Comin A Fertitta A Prada G Rubis Passoni P.A Testoni | 2001 | The American Journal of Gastroenterology2001，，2： | 4 |
| 2 | Liver angiogenesis as a risk factor for hepatocellularcarcinoma development in hepatitis C virus cirrhotic patients显示文摘AIM: To evaluate the predictive value of hepatocyte proliferation and hepatic angiogenesis for the occurrence of Hepatocellular carcinoma (HCC) in hepatitis C virus (HCV) cirrhotic patients. METHODS: One hundred-five patients (69 males, 36 females; age range, 51-90 year; median 66 year) with biopsy proven HCV cirrhosis were prospectively monitored for HCC occurrence for a median time of 64 mo. Angiogenesis was assessed by using microvessel density (MVD), hepatocyte turnover by MIB1 and PCNA indexes at inclusion in liver biopsies. RESULTS: Forty six patients (43.8%) developed HCC after a median time of 55 (6-120) mo while 59 (56.2%) did not. Patients were divided into two groups according to the median value of each index. The difference between patients with low (median MVD = 3; range 0-20) and high (median MVD = 7; range 1-24) MVD was statistically significant (χ2 = 22.06; P < 0.0001) which was not the case for MIB1 or PCNA (MIB-1: χ2 = 1.41; P = 0.2351; PCNA: χ2 = 1.27; P = 0.2589). The median MVD was higher in patients who developed HCC than in those who did not. HCC-free interval was significantly longer in patients with the MVD ≤ 4 (P = 0.0006). No relationship was found between MIB1 or PCNA and MVD (MIB-1 r2 = 0.00007116, P = 0.9281; PCNA: r2 =0.001950; P = 0.6692). MVD only was able to predict the occurrence of HCC in these patients. Among other known risk factors for HCC, only male sex was statistically associated with an increased risk. CONCLUSION: Liver angiogenesis has a role for in HCV- related liver carcinogenesis and for defining patients at higher risk. | Roberto Mazzanti Luca Messerini Camilla E Comin Lorenzo Fedeli Nathalie Gannè-Carrie Michel Beaugrand | 2007 | World Journal of Gastroenterology2007，13，37： | 3 |
| 3 | Effects of Composite β- and κ-Casein Genotypes on Milk Coagulation, Quality, and Yield Traits in Italian Holstein Cows显示文摘 | A. Comin M. Cassandro S. Chessa M. Ojala R. Dal Zotto M. De Marchi P. Carnier L. Gallo G. Pagnacco G. Bittante | 2008 | Journal of Dairy Science2008，，10： | 2 |
| 4 | An Exploration of Tech- nology Diffusion 显示文摘 | Comin Diego Hobijn Bart | 2010 | American Economic Review2010，100，5： | 1 |
| 5 | Effects of 3-amino-1,2,4-triazole on the inhibition of copper corrosion in acidic chloride solutions 显示文摘 | El-Sayed M Sherif Erasmus R M Comins J D | 2007 | Colloid and Interface Science2007，311，： | 1 |
| 6 | A 10-step, asymmetric synthesis of (S) -camptothecin 显示文摘 | Comins DL Baevsky MF Hong H | 1992 | JAm Chem Soc1992，114，10： | 1 |
| 7 | Serial changes in plasma levels of cytokines in patients with coronary artery disease显示文摘 | Heinisch RH Zanetti CR Comin F | 2005 | Vasc Health Risk Manag2005，1，3： | 1 |
| 8 | Evaluation of the an- tiviral activity of natural sulfated polyhydroxysteroids and their synthetic derivatives and analogs 显示文摘 | Comin M J Maier MS Roccatagliata AJ | 1999 | Steroids1999，64，5： | 1 |
| 9 | Cross-country technology adoption:making the theories face the facts显示文摘 | Comin D Hobijn B | 2004 | Journal of Monetary Economics2004，51，1： | 1 |
| 10 | Pathologic determinants of survival after resection of T3N0 (Stage IIA) colorectal cancer:proposal for a new prognostic model显示文摘 | Cianchi F Messerini L Comin CE | 2007 | Dis Colon Rectum2007，50，9： | 1 |
| 11 | Ferric ear- boxymaltose in patients with heart failure and iron deficiency 显示文摘 | ANKER S D COMIN COLET J FILIPPATOS G | 2009 | N Engl J Meal2009，361，25： | 1 |
| 12 | Asymmetric synthesis of camptothecin alkaloids: a nine-step synthesis of(S)-camptothecin 显示文摘 | Comins DL Hao H Gao JH | 1994 | Tetrahedron Left1994，35，30： | 1 |
| 13 | An exploration of technology diusion显示文摘 | Comin D Hobijn B | 2010 | The American Economic Review2010，100，5： | 1 |
| 14 | A practical six-step synthesis of (S) -camptothecin 显示文摘 | Comins DL Nolan JM | 2001 | Org Lett2001，3，26： | 1 |
| 15 | Nitrogen Removal and Cycling in Restored Wetlands Used as Filters of Nutrients for Agricultural Runoff显示文摘 | Comin F A | 1997 | Water Science and Technology1997，35，5： | 1 |
| 16 | PID Control: Recent Tuning Methods and Design to Specifieation显示文摘 | Comins P Munro N | 2002 | IEEE Pro- ceeding : Control Theory Application2002，149，1： | 1 |
| 17 | Integrating Objectives and Scales for Planning and Implementing Wetland Restoration and Crea-tion in Agricultural Landscapes显示文摘 | Moreno-Mateos D Comin F A | 2010 | Journal of Environmental Management2010，91，11： | 1 |
| 18 | Microvessel density and clinicopathological characteristics in hepatitis C virus and hepatitis B virus related hepatocellular carcinoma显示文摘 | Messerini L Novelli L Comin CE | 2004 | J Clin Pathol2004，57，8： | 1 |
| 19 | Complications of diagnostic and therapeutic ERCP: a prospective multicenter study显示文摘 | E Masci G Toti A Mariani S Curioni A Lomazzi M Dinelli G Minoli C Crosta U Comin A Fertitta A Prada G Rubis Passoni P.A Testoni | 2001 | The American Journal of Gastroenterology2001，，2： | 1 |
| 20 | Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly( ADP- ribose)polymerase activation in Jurkat T -cell leukemia tumor cells显示文摘 | Comin - Anduix B Boros LG Marin S | 2002 | The Journal of Biological Chemistry2002，277，46： | 1 |
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