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| 1 | Interactive labelling of a multivariate dataset for supervised machine learning using linked visualisations,clustering,and active learning显示文摘Supervised machine learning techniques require labelled multivariate training datasets.Many approaches address the issue of unlabelled datasets by tightly coupling machine learning algorithms with interactive visualisations.Using appropriate techniques,analysts can play an active role in a highly interactive and iterative machine learning process to label the dataset and create meaningful partitions.While this principle has been implemented either for unsupervised,semi-supervised,or supervised machine learning tasks,the combination of all three methodologies remains challenging.In this paper,a visual analytics approach is presented,combining a variety of machine learning capabilities with four linked visualisation views,all integrated within the mVis(multivariate Visualiser)system.The available palette of techniques allows an analyst to perform exploratory data analysis on a multivariate dataset and divide it into meaningful labelled partitions,from which a classifier can be built.In the workflow,the analyst can label interesting patterns or outliers in a semi-supervised process supported by active learning.Once a dataset has been interactively labelled,the analyst can continue the workflow with supervised machine learning to assess to what degree the subsequent classifier has effectively learned the concepts expressed in the labelled training dataset.Using a novel technique called automatic dimension selection,interactions the analyst had with dimensions of the multivariate dataset are used to steer the machine learning algorithms.A real-world football dataset is used to show the utility of mVis for a series of analysis and labelling tasks,from initial labelling through iterations of data exploration,clustering,classification,and active learning to refine the named partitions,to finally producing a high-quality labelled training dataset suitable for training a classifier.The tool empowers the analyst with interactive visualisations including scatterplots,parallel coordinates,similarity maps for records,and a new similarity map for partitions. | Mohammad Chegini Jürgen Bernard Philip Berger Alexei Sourin Keith Andrews Tobias Schreck | 2019 | Visual Informatics2019，3，1： | 3 |
| 2 | Severe acute respiratory syndrome coronavirus 2 infection: Role of interleukin-6 and the inflammatory cascade显示文摘Since December 2019,a novel coronavirus that represents a serious threat to human lives has emerged.There is still no definite treatment for severe cases of the disease caused by this virus,named coronavirus disease 2019(COVID-19).One of the most considered treatment strategies targets the exaggerated immune regulator,and interleukin(IL)-6 is a crucial pro-inflammatory mediator.Severe acute respiratory syndrome coronavirus 2(SARSCoV-2)cases show an elevated level of IL-6 related to disease severity.IL-6 activity can be inhibited by the following:IL-6 itself,IL-6 signaling pathways such as Janus kinase and signal transducer and activator of transcription(JAK-STAT),gp130,IL-6R,and downstream activated ILs,such as IL-17 and IL-6 cytokine.Currently,according to these studies and their results,IL-6 blockade with anti-IL-6 or its receptor antibodies such as tocilizumab in COVID-19 is beneficial in severe cases and may reduce the mortality rate.JAK-STAT inhibitors block the cytokine storm by inhibiting several crucial pro-inflammatory mediators such as TNF-αand IL-6 and have shown various results in clinical trials.IL-6 induces IL-17 secretion,and IL-17 is involved in the pathogenesis of inflammatory processes.Clinical trials of anti-IL-17 drugs are currently recruiting,and anti-gp130 antibody is preclinical.However,this agent has shown positive effects in inflammatory bowel disease clinical trials and could be tested for SARS-CoV-2.This study aimed to review the role of IL-6 in the cytokine storm and studies regarding IL-6 and blockade of its inflammatory pathways in COVID-19 to determine if any of these agents are beneficial for COVID-19 patients. | Mohaddeseh Bahmani Rojin Chegini Elham Ghanbari Elham Sheykhsaran Parisa Shiri Aghbash HamedEbrahimzadeh Leylabadlo Ehsan Moradian Amir Masoud Kazemzadeh Houjaghan Hossein Bannazadeh Baghi | 2022 | World Journal of Virology2022，11，3： | 2 |
| 3 | The expression of Smads in human endometrium and regulation and induction in endometrial epithelial and stromal cells by transforming growth factor-beta显示文摘 | Luo X Xu J Chegini N | 2003 | J Clin Endocrinol Metab2003，88，10： | 1 |
| 4 | Detection of bone erosion in early rheumatoid arthritis: ultrasonography and conventional radiography versus non-contrast magnetic resonance imaging 显示文摘 | Rahmani M Chegini H Najafizadeh SR | 2010 | Clin Rheumatol2010，29，8： | 1 |
| 5 | Physical and mechanical properties in biodegradable films of whey protein concentrate–pullulan by application of beeswax显示文摘 | Mehrdad Khanzadi Seid Mahdi Jafari Habibollah Mirzaei Faramarz Khodaian Chegini Yayha Maghsoudlou Danial Dehnad | 2015 | Carbohydrate Polymers2015，，： | 1 |
| 6 | Morphological and biochemical characterization of small and large bovine luteal cells during pregnancy显示文摘 | Chegini N Ramani N Rao C V | 1984 | Mol Cell Endocrinol1984，37，1： | 1 |
| 7 | Notice of Retraction of microRNA 21 : response to hormonal therapies and regulatory function in leiomyo- ma, transformed leiomyoma and leiomyosarcoma cells 显示文摘 | Pan Q Luo X Chegini N | 2010 | Mol Hum Reprod2010，16，3： | 1 |
| 8 | Direct enzyme-linked immune-sorbent assay and a radioimmunoassay for melatonin compared显示文摘 | CHEGINI S EHRHART-HOFMANN B KAIDER A | 1995 | Oin Chem1995，41，3： | 1 |
| 9 | Role of transfor raing growth factor beta-1 in peritonitis-induced adhesions 显示文摘 | Ghellai AM Stucehi AF Chegini N | 2000 | J Gastrointest Surg2000，4，3： | 1 |
| 10 | The expression of Smads in humanen- dometrium and regulation and induction in endometrial epithelialand stromal cells by transforming growth factor-beta显示文摘 | Luo X Xu J Chegini N | 2003 | J Clin Endocrinol Metab2003，88，10： | 1 |
| 11 | A novel alternative method for modeling the effects of air temperature and slice thickness on quality and drying kinetics of tomato slices:Superposition technique显示文摘 | Khazaei J Chegini G-R Bakhshiani M | 2008 | Drying Technology2008，26，6： | 1 |
| 12 | Expression of integrin messenger ribonucleic acid in human endometrium:a quantitative reverse transcription polymerase chain reaction study显示文摘 | Dou Q Willians RS Chegini N | 1999 | Fertil Steril1999，71，2： | 1 |
| 13 | Effects of GnRH analogues,“add-back”steroid therapy,antiestrogen and antiprogestins on leiomyoma and myometrial smooth muscle cell growth and transforming growth factor-expression显示文摘 | Chegini N Ma C Tang XM | 2002 | Mol Hum Reprod2002，8，： | 1 |
| 14 | Expression of messenger ribonucleic acid and presence of immunoreactive proteins for epidermal growth factor (EGF), transforming growth factor alpha(TGFa) and EGF/TGFa receptors and 125^I-EGF binding sites in human fallopian tube 显示文摘 | Chegini N Zhan Y Mclean F W | 1994 | Biol Reprod1994，50，： | 1 |
| 15 | Expression of integrin messenger ribonucleic acid in human endometrium:a quantitative reverse transcription polymerase chain reaction study显示文摘 | Dou Q Williams RS Chegini N | 1999 | Fertil Steril1999，71，2： | 1 |
| 16 | Design and construction of a harvesting safflower petals machine 显示文摘 | Siavash Azimi Gholamreza Chegini Mohamad Hosein Kian- mehr | 2012 | Iranian journal of Range and Desert Re- seach2012，14，2： | 1 |
| 17 | Prediction of process and product parameters in an orange juice spray dryer using artificial neural networks显示文摘 | Chegini G R Khazaei J Ghobadian B | 2008 | Journal of Food Engineering2008，84，4： | 1 |
| 18 | Detection of bone erosion in early rheumatoid arthritis: uhrasonography and conventional radiography versus non-contrast magnetic resonance imaging 显示文摘 | Rahmani M Chegini H Najafizadeh SR | 2010 | Clin Rheumatol2010，29，88： | 1 |
| 19 | Pre-operative blood donation versus acute normovolemic hemodilution in cardiac surgery显示文摘 | Mohammad Nobahar Azita Chegini Faranak Behnaz | 2014 | Saudi Journal of Anaesthesia2014，，3： | 1 |
| 20 | Differential expression of interleukins (IL)-13 and IL-15 in eetopie and eutopic endometrium of women with endometriosis and normal fertile women 显示文摘 | CHEGINI N ROBERTS M RIPPS B | 2003 | Am J Reprod Immunol2003，49，2： | 1 |
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