|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 紫杉醇局部治疗抑制猪静脉桥新生内膜形成和增厚的实验研究显示文摘目的 :局部药物治疗是一个很好的防治静脉桥病变的策略。本研究用抗细胞增殖药物紫杉醇处理大隐静脉桥后植入猪的颈动脉 ,以观察紫杉醇的抗细胞增殖作用在抑制静脉桥内膜平滑肌细胞增殖、迁移导致内膜形成和增厚的效果。方法 :将 10头猪的 2 0只大隐静脉桥分为两组。治疗组 :将大隐静脉桥 10只置于含有 10 μmol/L浓度的紫杉醇溶液中 (先用该溶液灌洗 )浸泡 1h后植入猪的颈动脉 ,紫杉醇是溶解在 2 5 μl/L的无水酒精中 ,对照组 10只大隐静脉桥置于单纯的酒精中浸泡。 4周后取开放的静脉桥进行组织学分析。结果 :①治疗组静脉桥新生内膜面积 (1 5 9± 0 95 )mm2 ,对照组新生内膜面积高达 (2 43± 1 3 5 )mm2 ,治疗组显著低于对照组 ,两组比较有非常显著的差异 ,P <0 0 1;②治疗组内膜平滑肌细胞密度均值为 (3 681± 193 5 ) /mm2 ,对照组为 (4 60 7± 1993 ) /mm2 ,两组比较有显著性差异 ,P <0 0 5 ;中膜平滑肌细胞密度均值治疗组 (2 13 9± 73 4) /mm2 ,对照组(3 62 9± 3 2 0 7) /mm2 ,两组比较有显著性的差异 ,P <0 0 5。结论 :紫杉醇可显著抑制静脉桥内膜、中膜平滑肌细胞的增殖 ,抑制新生内膜的形成 ,证明紫杉醇可在防治静脉桥闭塞方面发挥独特作用。 | 吴隐雄 Martin H Chamberlain Thomas Johnson Jason L Johnson Andrew C Newby Gianni D Angelin Martin Oberhoff Karl K Karsch | 2003 | 中国循环杂志2003，18，6： | 2 |
| 2 | Presence of fetal DNA in maternal plasma and serum显示文摘 | Y M Dennis Lo Noemi Corbetta Paul F Chamberlain Vik Rai Ian L Sargent Christopher WG Redman James S Wainscoat | 1997 | The Lancet1997，，9076： | 2 |
| 3 | Low-temperature densiflcation of zirconium diboride ceramics by reactive hot pressing 显示文摘 | Chamberlain A L Fahrenheltz W G Hilmas G E | 2006 | J Am Chem Soc2006，89，12： | 1 |
| 4 | Temporal trends in the occurrence and outcomes of atrial fibrillation in patients with acute myocardial infarction (from the Atherosclerosis Risk in Communities Surveil- lance Study) 显示文摘 | Bengtson L G Chen L Y Chamberlain A M | 2014 | Am J Cardiol2014，114，5： | 1 |
| 5 | GFP tagged pollen to monitor pollen flow of transgenic plants显示文摘 | Hudson L C Chamberlain D Stewart Jr C N | 2001 | Molecular Ecology Notes2001，1，： | 1 |
| 6 | Low-temperature Densification of Zirconium Diboride Ceramics by Reactive Hot Pressing显示文摘 | Chamberlain A L Fahrenholtz W G Hilmas G E | 2006 | Journal of the American Ceramic Society2006，89，12： | 1 |
| 7 | White matter abnormalities in patients with obsessive-compulsive disorder and their first-degree relatives显示文摘 | Menzies L Williams GB Chamberlain SR | 2008 | Am J Psychiatry2008，165，10： | 1 |
| 8 | Heat-producing elements and the thermal and baric patterns of metamorphic belts显示文摘 | Chamberlain C P Sonder L J | 1990 | Science1990，250，： | 1 |
| 9 | Suggestions for HER2/neu testing in breast carcinoma,based on a comparison of immunohistochemistry and fluorescence in situ hybridisation显示文摘 | Field A S Chamberlain N L Tran D | 2001 | Pathology2001，33，3： | 1 |
| 10 | Atomic vibrations and the melting process in metals 显示文摘 | Melachlan J D Chamberlain L L | 1964 | Acta Metallurgica1964，12，5： | 1 |
| 11 | Flying fast and low among obstacles: methodology and experiments显示文摘 | Scherer S Singh S Chamberlain L | 2008 | The Inter- national Journal of Robotics Research2008，27，5： | 1 |
| 12 | Hi|ar cholangioearcinoma: a review and commentary 显示文摘 | Chamberlain R S Blumgart L H | 2000 | Ann Surg Oncol2000，7，1： | 1 |
| 13 | Autonomous Landing at Unprepared Sites by a Full-scale Helicopter 显示文摘 | Scherer S Chamberlain L Singh S | 2012 | Robotics and Autonomous Systems2012，60，12： | 1 |
| 14 | Carbon Isotopes Reveal Soil Organic Matter Dynamics Following arid Land Shrub Expansion显示文摘 | Connin S L Virginia R A Chamberlain C P | 1997 | Oecologia1997，110，： | 1 |
| 15 | Oral vaccination of mice against tetanus with recombinant Lactococcus lactis 显示文摘 | Robinson K Chamberlain L M Schofietd K M | 1997 | Nat Biotechnol1997，15，： | 1 |
| 16 | AXOR12 a novel human G protein coupled receptor, activated by the pep- tide KiSS-1显示文摘 | Muir AI Chamberlain L Elshourbagy NA | 2001 | J Biol Chem2001，276，28： | 1 |
| 17 | Mechanisms of parturition:The transfer of prostaglandin E2 and 5-hydroxyeicoas tetraenoic acid across fetal membranes显示文摘 | Bennett PR Chamberlain GV Patel L | 1990 | Am J Obstet Gynecol1990，162，3： | 1 |
| 18 | Reactive Hot Pressing of Zirconium Diboride显示文摘 | Chamberlain A L Fahrenholtz W G Hilmas G E | 2009 | Journal of the European Ceramic Society2009，29，16： | 1 |
| 19 | Inhibition of isoprenoid biosynthesis causes insulin resistance in 3T3-L1adipocytes显示文摘 | CHAMBERLAIN L H | 2001 | FEBS Lett2001，507，： | 1 |
| 20 | AXOR12,a novel human G protein-coupled receptor, activated by the peptide KiSS-1显示文摘 | Chamberlain L Elshourbagy N A | 2001 | J Biol Chem2001，276，28： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员